A5100782764- HIV Research and Treatment
- Paraquat toxicity studies and treatments
- HIV/AIDS drug development and treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Lung Cancer Treatments and Mutations
- COVID-19 Clinical Research Studies
- Plant-based Medicinal Research
- Endometriosis Research and Treatment
- Lung Cancer Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Testicular diseases and treatments
- SARS-CoV-2 and COVID-19 Research
- Omental and Epiploic Conditions
- Uterine Myomas and Treatments
- Neuroblastoma Research and Treatments
- Myasthenia Gravis and Thymoma
- Polymer Surface Interaction Studies
- PARP inhibition in cancer therapy
- Thermal Regulation in Medicine
- Long-Term Effects of COVID-19
- Pulmonary Hypertension Research and Treatments
- Moyamoya disease diagnosis and treatment
- Cerebrovascular and Carotid Artery Diseases
- Thermoregulation and physiological responses
- Acute Kidney Injury Research
Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2024
Peking Union Medical College Hospital
2016-2024
Guangdong Provincial People's Hospital
2024
First Affiliated Hospital of Hebei Medical University
2022
Harrison International Peace Hospital
2017-2020
Institute of Microbiology
2009-2020
First Affiliated Hospital of Dalian Medical University
2017-2020
Dalian Medical University
2017-2020
Czech Academy of Sciences, Institute of Microbiology
2020
Capital University
2020
Ebola virus has been detected in the semen of men after their recovery from disease (EVD). We report presence RNA a cohort survivors EVD Sierra Leone.We enrolled convenience sample 220 adult male Leone, at various times discharge an treatment unit (ETU), two phases (100 participants were phase 1, and 120 2). Semen specimens obtained baseline tested by means quantitative reverse-transcriptase-polymerase-chain-reaction (RT-PCR) assay with use target sequences NP VP40 (in 1) or GP This study...
Nanoparticles with tunable pharmacokinetics are desirable for various biomedical applications. Poly(ethylene glycol) (PEG) is well-known to create "stealth" effects stabilize and extend the blood circulation of nanoparticles. In this work, poly(carboxybetaine) (PCB), a new nonfouling polymer material, was incorporated as surface-grafted coatings, conjugated onto degradable shell cross-linked knedel-like nanoparticles (dSCKs) composed poly(acrylic acid)-based shells poly(lactic acid) cores,...
Objectives: A common potentially fatal disease of the pancreas is acute pancreatitis, for which there no treatment. Most studies this disorder focus on damage to acinar cells since they are assumed be primary target multiple stressors affecting pancreas. However, increasing evidence suggests that ducts may also have a crucial role in induction disease. To test hypothesis, we sought determine specific duct pancreatitis using well-established models and mice with deletion Na+/H+ exchanger...
Objective: To explore the appropriate treatment of malignant germ cell tumor (MGCT) in female genital system, and to analyze factors influencing both therapeutic response survival outcome.Methods: A cohort 230-Chinese women diagnosed with MGCT system was retrospectively reviewed prospectively followed.The demographic pathological features, extent disease surgery, efficiency, recurrence were analyzed.Results: MGCTs from different origins shared a similar strategy response, except that all...
Shenzhen City is a rapidly growing area with large number of floating populations, thus making it difficult to control HIV. Serial cross-sectional studies are helpful for the prediction epidemiological tendency. In this study, two parallel were compared explore changes in HIV epidemiology Shenzhen, China.Two hundred and fifty newly reported HIV-positive cases randomly selected 2013 2015. Socio-demographical information was collected informed consent. Full-length gag partial pol genes...
Objective: The objective of this study was to investigate the characteristics 24-hour ambulatory blood pressure monitoring and its relationship with cardiovascular target organ damage (left ventricular hypertrophy carotid atherosclerosis) in Chinese Han patients concomitant type 2 diabetes mellitus hypertension. Methods: A total 830 hypertensive or without were divided into four groups according patterns. Clinical indexes compared among groups. Multivariable logistic regression used identify...
// Qianying Zhao 1 , Dongyan Cao Mei Yu Jiaxin Yang Yongjian Liu 2 Xiang Ming Wu Lingya Pan Jinghe Lang Kaifeng Xu Jiangna Han and Keng Shen Department of Gynecology Obstetrics, Peking Union Medical College Hospital, Chinese Academy Sciences & College, Beijing, China Respiratory Medicine, Correspondence to: Shen, email: Han, Zhao, Keywords : bleomycin, medication safety, treatment efficacy, pulmonary toxicity, malignant germ cell tumor Received October 15, 2016 Accepted January 09, 2017...
Abstract Background There is increasing evidence that HIV-1 genetic diversity can have an impact on drug resistance. The aim of this study to investigate the epidemiological situation CRF65_cpx and natural polymorphisms variant genotypic Methods We used BLAST search program followed by phylogenetic analysis identify additional pol sequences from Los Alamos HIV Sequence Database. Maximum likelihood phylogeny was estimated clarify relationship strains. Genotypic resistance determined...
Treatments for very small (3 mm or smaller) intracranial aneurysms (VSAs) remain controversial. The aim of this study was to evaluate the efficacy endovascular treatment VSAs and clinical risk factors associated with complications. This retrospective enrolled 82 VSA patients who underwent coil embolization in our institution. Angiographic outcomes were assessed according Meyers classification. results evaluated using modified Rankin scale (mRS) immediately after coiling, at discharge, during...
Both fibrosing mediastinitis (FM) and bronchial anthracofibrosis (BAF) are unique diseases. The combined appearance of FM BAF is extremely rare.The aim this study was to investigate the clinical features patients with coexisting BAF.Between January 2003 December 2015, a total eight were diagnosed at Peking Union Medical College Hospital as having BAF. presentations, radiographic bronchoscopic findings reviewed.The five women three men median age 64 years (range 56-86 years). Symptoms...
To observe the effect of rhubarb as main composition in therapy for patients with acute paraquat poisoning (AP).A prospective randomized controlled trial was conducted. 128 APP admitted to Harrison International Peace Hospital from March 2011 December 2013 were randomly divided into western medicine control group (n = 64) and traditional Chinese (TCM) combination 64). All treated repeated gastric lavage oral kaolin. The given 20% mannitol (or) magnesium sulfate catharsis, early ( within 8...
Pneumonic-type lung carcinoma is a special type of cancer both clinically and radiologically. Here we present our experience on pneumonic-type in an attempt to investigate the clinical, radiological pathological features, diagnostic procedures, treatment, prognosis this tumor. Pathologically confirmed with chest CT characterized by ground glass opacity or consolidation was defined as carcinoma. Cases advanced admitted Peking Union Medical College Hospital (PUMCH) from January 1, 2013 August...
Abstract Background Severe acute respiratory syndrome coronavirus 2 will coexist with humans for a long time, and it is therefore important to develop effective treatments disease 2019 (COVID-19). Recent studies have demonstrated that antiviral therapy key factor in preventing patients from progressing severe disease, even death. Effective affordable medications are essential treatment urgently needed. Azvudine, nucleoside analogue, potential low-cost candidate few drug interactions....
The rapid spread of the coronavirus disease 2019 (COVID-19) has become a global threat. But pathogenesis and treatment are not clear yet. Virological researches revealed close relationship between 2019-nCoV SARS-CoV. experience knowledge we gained from severe acute respiratory syndrome (SARS), especially with regard to time course viral replication, host immune response clinical progression patient, may provide important insights into understanding management COVID-19. Clinical deterioration...
Background Low dose computed tomography (LDCT) for lung cancer screening is widely employed in China as a result of increasing awareness. Although some pulmonary lesions detected by LDCT are cancerous, most the nodules benign. It important to make effective preoperative differentiation and obviate need surgery patients with benign disease. Methods From January 1, 2017 December 31, 2018, our institution surgical pathology confirmed which malignancy could not be excluded assessment were...
To investigate the clinical effect of paraquat (PQ) detoxification recipe combined with continuous hemoperfusion (HP) in treatment patients acute poisoning (APP) and significance soluble CD14 subtype (sCD14-st, Presepsin).A prospective randomized controlled trial was conducted. 152 moderate APP admitted to Department Emergency Medicine Harrison International Peace Hospital Affiliated Hebei Medical University from July 2013 June 2017 were enrolled, they randomly divided into three groups. The...
To detect the expression of inflammatory factors such as interleukin‐1 β (IL‐1 ), interleukin‐6 (IL‐6), transforming growth factor (TGF‐ and tumor necrosis (TNF‐ α ) in tissue ventricular septal defect (VSD) congenital heart disease to explore role response formation aneurysmal perimembranous VSD(APVSD). Children with APVSD treated by surgery were selected divided into true group (TAP group) pseudoaneurysmal (PAP according echocardiography surgical findings. There 15 children TAP 31 PAP...
Objective To investigate the relationship between soluble CD14-st(Presepsin) and assessment, prognosis in patients with acute paraquat poisoning(APP). Methods A total of 82 APP treated Emergency Department Harrison International Peace Hospital Affiliated to Hebei Medical University from January 2013 2016 were divied into three groups: mild poisoning group (n=20), moderate (n=36) severe (n=26). According outcomes, divided survivor (n=28) non-survivor (n=54). Another 50 healthy subjects...
Objective: To explore the evaluate of neutrophil gelatinase-associated lipocalin (NGAL) , combined with neutrophil/lymphocyte ratio (NLR) in early prognosis patients acute paraquat poisoning (APP) . Methods: In March 2019, 108 APP admitted to Emergency Medicine Department Hebei Medical University from January 2017 December 2018 were selected as observation group, 60 healthy people same period see control group according results diagnosis and 28-day survival, was divided into 51 death 57...