Carmela Gissi
- Marine Ecology and Invasive Species
- Genomics and Phylogenetic Studies
- Identification and Quantification in Food
- Marine Biology and Environmental Chemistry
- Genetic diversity and population structure
- RNA and protein synthesis mechanisms
- Mitochondrial Function and Pathology
- Environmental DNA in Biodiversity Studies
- Microbial Community Ecology and Physiology
- Marine Invertebrate Physiology and Ecology
- SARS-CoV-2 and COVID-19 Research
- Protist diversity and phylogeny
- RNA Research and Splicing
- Bacteriophages and microbial interactions
- RNA modifications and cancer
- Metabolomics and Mass Spectrometry Studies
- Evolution and Paleontology Studies
- Developmental Biology and Gene Regulation
- Regional resilience and development
- Biocrusts and Microbial Ecology
- Metabolism and Genetic Disorders
- Parasite Biology and Host Interactions
- Genetics, Bioinformatics, and Biomedical Research
- Aquatic life and conservation
- Genetic Mapping and Diversity in Plants and Animals
Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies
2017-2024
University of Bari Aldo Moro
2000-2024
CoNISMa
2020-2024
National Academies of Sciences, Engineering, and Medicine
2020
University of Milan
2006-2015
RELX Group (United Kingdom)
2007
Bethesda University
2007
Lund University
1996
Only a small proportion of the mouse genome is transcribed into mature messenger RNA transcripts. There an international collaborative effort to identify all full-length mRNA transcripts from mouse, and ensure that each represented in physical collection clones. Here we report manual annotation 60,770 complementary DNA sequences. These are clustered 33,409 'transcriptional units', contributing 90.1% newly established transcriptome database. Of these transcriptional units, 4,258 new...
Cephalochordates, urochordates, and vertebrates evolved from a common ancestor over 520 million years ago. To improve our understanding of chordate evolution the origin vertebrates, we intensively searched for particular genes, gene families, conserved noncoding elements in sequenced genome cephalochordate Branchiostoma floridae, commonly called amphioxus or lancelets. Special attention was given to homeobox opsin genes involved neural crest development, nuclear receptor encoding components...
The base composition of 25 complete mammalian mitochondrial (mt) genomes has been analyzed taking into account all three codon positions (P1230 and fourfold degenerate sites (P4FD) H-strand genes. In the nontranscribed L strand, G is less represented A most one in cases, while C T differ among species. protein-coding genes show an asymmetric distribution four bases between two strands. asymmetry indexes AT GC skews on P4FD are much higher than those P123, suggesting existence asymmetrical...
Ciona intestinalis is considered a widespread and easily recognizable tunicate, the sister group of vertebrates. In recent years, molecular studies suggested that C. includes at least two cryptic species, named 'type A' B', morphologically indistinguishable. It dramatic to certify different species may be hidden under name widely used as model in biological researches. This raised problem identifying diagnostic morphological characters capable distinguishing these types. We compared...
Botryllus schlosseri is a colonial urochordate that follows the chordate plan of development following sexual reproduction, but invokes stem cell-mediated budding program during subsequent rounds asexual reproduction. As urochordates are considered to be closest living invertebrate relatives vertebrates, they ideal subjects for whole genome sequence analyses. Using novel method high-throughput sequencing eukaryotic genomes, we sequenced and assembled 580 Mbp B. genome. The assembly comprised...
The cosmopolitan ascidian Ciona intestinalis is the most common model species of Tunicata, sister-group Vertebrata, and widely used in developmental biology, genomics evolutionary studies. Recently, molecular studies suggested presence cryptic hidden within C. species, namely type A B. So far, no substantial morphological differences have been identified between individuals belonging to two types. Here we present morphometric, immunohistochemical, histological analyses, as well 3-D...
A genomic database of all Earth's eukaryotic species could contribute to many scientific discoveries; however, only a tiny fraction have information available. In 2018, scientists across the world united under Earth BioGenome Project (EBP), aiming produce high-quality reference genomes containing ~1.5 million recognized species. As European node EBP, Reference Genome Atlas (ERGA) sought implement new decentralised, equitable and inclusive model for producing genomes. For this, ERGA launched...
Abstract The GAS multigene family of Saccharomyces cerevisiae is constituted by five genes ( GAS1–GAS5 ), but GAS1 was the only one to have been characterized date. Gas1 a glycosylphosphatidylinositol‐anchored protein predominantly localized in plasma membrane and also representative GH72 glycosidase/transglycosidases, wide group yeast fungal enzymes involved cell wall assembly. Gas1–Gas5 proteins share common N‐terminal domain exhibit different C‐terminal extensions, which named Cys‐Box...
Botryllus schlosseri is a widespread colonial ascidian commonly considered cosmopolitan and amply used as model for researches ranging from developmental biology to immunobiology. Recently, molecular data lead hypothesize that the species named B. may consist of more than single taxon. Indeed, five highly divergent clades, A-E, have been genetically identified are referred cryptic species. In this context, lacking both type detailed morphological description, we believe it necessary,...
Ascidians belong to the tunicates, sister group of vertebrates and are recognized model organisms in field embryonic development, regeneration stem cells. ANISEED is main information system ascidian developmental biology. This article reports development since its initial publication 2010. Over past five years, we refactored from an custom schema extended version Chado redesigned all user back end interfaces. new architecture was used improve enrich description Ciona intestinalis based on...
The rapid expansion of multicellular native and alien species outbreaks in aquatic terrestrial ecosystems (bioinvasions) may produce significant impacts on bacterial community dynamics nutrient pathways with major ecological implications. In ecosystems, bioinvasions cause adverse effects the water quality resulting from changes biological, chemical physical properties linked to transformations microbial taxonomic functional diversity. Here we used an effective highly sensitive experimental...
The 16S rRNA amplicon-based sequencing approach represents the most common and cost-effective strategy with great potential for microbiome profiling. use of second-generation (NGS) technologies has led to protocols based on amplification one or a few hypervariable regions, impacting outcome analysis. Nowadays, comparative studies are necessary assess different approaches, including full-locus currently feasible thanks third-generation (TGS) technologies. This study compared three methods...
The existence of a lineage-specific nucleotide substitution rate in mammalian mtDNA has been investigated by analyzing the all available species, that is, 35 complete mitochondrial genomes from 14 orders. A detailed study their evolutionary dynamics carried out on both ribosomal RNA and first second codon positions (P12) H-strand protein-coding genes using two different types relative-rate tests. Results are quite congruent between P12 sites. Significant variations have observed among orders...