A5023715229- Mass Spectrometry Techniques and Applications
- Protein purification and stability
- Advanced Proteomics Techniques and Applications
- Radioactive Decay and Measurement Techniques
- CRISPR and Genetic Engineering
- Cancer Genomics and Diagnostics
- Metabolomics and Mass Spectrometry Studies
- Neurogenesis and neuroplasticity mechanisms
- Single-cell and spatial transcriptomics
- Body Composition Measurement Techniques
- Clinical Laboratory Practices and Quality Control
- Bone Tissue Engineering Materials
- Orthopaedic implants and arthroplasty
- Axon Guidance and Neuronal Signaling
- Traditional Chinese Medicine Studies
- Polymer Surface Interaction Studies
- Nerve injury and regeneration
Instituto Nacional de Metrologia, Qualidade e Tecnologia
2014-2024
Universidade Federal do Rio de Janeiro
2011
The health of their populations and efficient care systems are critical importance to the economic social well-being nations. Accurate comparable peptide/protein measurements required in support diagnosis, prognosis, monitoring treatment widespread diseases (e.g. diabetes). consistency measurement results can be achieved by making them traceable stated references through development Reference Measurement Systems. review mainly concentrates on progress made Protein Analysis Working Group...
Background It is known that physico/chemical alterations on biomaterial surfaces have the capability to modulate cellular behavior, affecting early tissue repair. Such surface modifications are aimed improve healing response and, clinically, offer possibility shorten time from implant placement functional loading. Since FAK and Src intracellular proteins able predict quality of osteoblast adhesion, this study evaluated behavior in nanometer scale titanium texturing by monitoring...
The amyloid precursor protein (APP) is well known for giving rise to the amyloid-β peptide and its role in Alzheimer's disease. Much less known, however, on physiological roles of APP development plasticity central nervous system. We have used phage display a library identify high-affinity ligands purified recombinant human sAPPα695 (the soluble, secreted ectodomain from main neuronal isoform). Two peptides thus selected exhibited significant homologies with conserved extracellular domain...
ABSTRACT For the impact of genomic testing from liquid biopsies to be maximized, mechanisms ensure reproducible and comparable test performance will required. This can established maintained through reference measurement procedures materials with property values that are internationally traceability a common standard. To achieve this objective, an interlaboratory study was organised explore digital PCR (dPCR) for standardisation cell-free DNA (cfDNA) quantification. Blinded samples...
Main text Under the auspices of Protein Analysis Working Group (PAWG) Comité Consultatif pour la Quantité de Matière (CCQM) a pilot study, CCQM-P201, was organised. Five National Metrology Institutes (NMIs) participated in this study and provided total eleven measurement results using six different methods based on three principles. The purpose to develop capabilities for accurate quantification intact haemoglobin (Hb) whereby could be made directly traceable SI. choice protein resulted from...
Main text Under the auspices of Protein Analysis Working Group (PAWG) Comité Consultatif pour la Quantité de Matière (CCQM) a key comparison, CCQM-K115.c, was coordinated by Bureau International des Poids et Mesures (BIPM), Health Sciences Authority (HSA) Singapore and Chinese National Institute Metrology (NIM). Nine Institutes or Designated BIPM participated. Participants were required to assign mass fraction glycated hexapeptide HbA1c (GE) present as main component in comparison sample for...
Main text Under the auspices of Protein Analysis Working Group (PAWG) Comité Consultatif pour la Quantité de Matière (CCQM) a key comparison, CCQM-K115.2018, was coordinated by Bureau International des Poids et Mesures (BIPM), Health Sciences Authority (HSA) Singapore and Chinese National Institute Metrology (NIM). Ten Institutes or Designated BIPM participated. Participants were required to assign mass fraction hexapeptide HbA0 (VE) present as main component in comparison sample for...
Main text The key comparison CCQM-K151 protein quantification: Purity-assessed recombinant contents in buffer solution using Insulin analogue was coordinated by Korea Research Institute of Standards and Science (KRISS) under the auspices Protein Analysis Working Group (PAWG) Consultative Committee for Amount Substance: Metrology Chemistry Biology (CCQM) CCQM. Nine National Institutes Designated participated. Participants were required to assign mass fraction human insulin (Ins) present as...