Lê Thanh Hải

ORCID: 0000-0002-2486-8467
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Research Areas
  • Research studies in Vietnam
  • Sepsis Diagnosis and Treatment
  • Respiratory Support and Mechanisms
  • Pediatric health and respiratory diseases
  • Structural mechanics and materials
  • Geodetic Measurements and Engineering Structures
  • Respiratory viral infections research
  • Neonatal and fetal brain pathology
  • Multi-Criteria Decision Making
  • Mosquito-borne diseases and control
  • Infectious Encephalopathies and Encephalitis
  • Influenza Virus Research Studies
  • Nosocomial Infections in ICU
  • Advanced Theoretical and Applied Studies in Material Sciences and Geometry
  • Lysosomal Storage Disorders Research
  • Immunodeficiency and Autoimmune Disorders
  • Tuberculosis Research and Epidemiology
  • Blood Coagulation and Thrombosis Mechanisms
  • Streptococcal Infections and Treatments
  • Bacterial biofilms and quorum sensing
  • Emergency and Acute Care Studies
  • Antimicrobial Resistance in Staphylococcus
  • Viral Infections and Immunology Research
  • Child Nutrition and Feeding Issues
  • Thermal Regulation in Medicine

Hanoi Medical University
2024

National Hospital of Pediatrics
2012-2021

Ministry of Health
2018

National Institute of Infectious Diseases
2016

Southwest University
2011

General Department of Preventive Medicine
2009

Purpose: Staphylococcus aureus is a commensal bacteria species that can cause various illnesses, from mild skin infections to severe diseases, such as bacteremia. The distribution and antimicrobial resistance (AMR) pattern of S. varies by population, time, geographic location, hospital wards. In this study, we elucidated the epidemiology AMR patterns isolated general in Vietnam. Methods: This was cross-sectional study. Data on all 2014 2021 were collected Microbiology department Military...

10.2147/idr.s437920 article EN cc-by-nc Infection and Drug Resistance 2024-01-01

During an outbreak of severe acute respiratory infections in 2 orphanages, Vietnam, 7/12 hospitalized children died. All and 26/43 from orphanages tested positive for rhinovirus versus 9/40 control (p = 0.0005). Outbreak rhinoviruses formed a distinct genetic cluster. Human is underappreciated cause pneumonia vulnerable groups.

10.3201/eid1811.120607 article EN cc-by Emerging infectious diseases 2012-10-03

Background Infections with community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) are emerging worldwide. We investigated an outbreak of severe CA-MRSA infections in children following out-patient vaccination. Methods and Findings carried out a field investigation after adverse events immunization (AEFI) were reported. reviewed the clinical data from all cases. S. recovered skin nasal throat swabs analyzed by pulse-field gel electrophoresis, multi locus sequence typing, PCR...

10.1371/journal.pone.0000822 article EN cc-by PLoS ONE 2007-09-04

Background Between 2003 and 2005, highly pathogenic avian influenza A (H5N1) viruses caused large scale outbreaks in poultry the Ho Chi Minh City area Vietnam. We studied prevalence of antibodies against H5N1 workers cullers who were active program 2004 2005. Methodology/Principal Findings Single sera from 500 exposed to infected birds tested for H5N1, using microneutralization assays hemagglutination inhibition assay with horse blood. All negative tests. Three samples showed a 1∶80 titer...

10.1371/journal.pone.0007948 article EN cc-by PLoS ONE 2009-11-20

Abstract During a 2014 measles outbreak in Vietnam, postmortem pathologic examination of hospitalized children who died showed that adenovirus type 7 pneumonia was contributory cause death with measles-associated immune suppression. Adenovirus should be recognized as major secondary infection after measles.

10.3201/eid2204.151595 article EN cc-by Emerging infectious diseases 2016-03-01

The overall goal of the Supporting Adolescent Adherence in Vietnam (SAAV) study is to improve understanding an adherence feedback mHealth intervention designed help adolescents living with HIV (ALHIV) maintain high antiretroviral therapy (ART), critical effective treatment. Specifically, we aim to: (1) conduct formative research Vietnamese ALHIV and their caregivers better understand challenges refine personalized package; (2) assess feasibility, acceptability, efficacy ART by implementing a...

10.1186/s13063-019-3239-1 article EN cc-by Trials 2019-02-28

Pertussis is an infectious disease that causes epidemics and outbreaks associated with a high mortality rate, especially in infants, both developed developing countries. We aimed to characterize infants pertussis respiratory failure shock investigated the factors related mortality.A retrospective, observational study conducted between January 2015 October 2020.This was at Vietnam National Children's Hospital, which government hospital serves as tertiary care center Hanoi, Vietnam.Children...

10.1097/pcc.0000000000002723 article EN Pediatric Critical Care Medicine 2021-04-02

Abstract Seasonal human influenza viruses continually change antigenically to escape from neutralizing antibodies. It remains unclear how genetic variation in the intrahost virus population and selection at level of individual hosts translates fast-paced evolution observed global because emerging antigenic variants are rarely detected. We tracked hemagglutinin neuraminidase surface proteins using longitudinally collected samples 52 patients infected by A/H3N2 virus, mostly young children,...

10.1093/ve/veaa088 article EN cc-by-nc Virus Evolution 2020-07-01

Background: Adolescents living with HIV (ALHIV) in Vietnam are known to struggle adherence Antiretroviral Therapy (ART). Objective: To examine treatment challenges and facilitators experienced by ALHIV from the perspective of adolescents, their caregivers, providers, inform an intervention. Methods: In-depth Interviews (IDIs) adolescent/caregiver dyads Focus Group Discussions (FGDs) clinicians were conducted Hanoi, Vietnam. We used semi-structured guides encourage open-ended responses....

10.2174/1874613602014010114 article EN The Open AIDS Journal 2020-12-23

Introduction: Global health agencies and the Vietnam Ministry of Health have identified pediatric emergency care information technology as high priority goals. Clinical decision support (CDS) software provides physicians with access to current literature answer clinical queries, but there is limited impact data in developing countries. We hypothesized that Vietnamese will demonstrate improved test performance on common emergencies using CDS technologies despite being English.Methods: This...

10.5811/westjem.2013.4.15090 article EN cc-by Western Journal of Emergency Medicine 2013-09-17

Wilson disease (OMIM # 277900) is a autosomal recessive disorder characterized by accumulation of copper in liver and brain. The resulting oxidative stress eventually cell death. has an onset childhood result significant neurological impairment or require lifelong treatment. Another serious consequence the development damage acute failure leading to transplant. caused mutations ATP7B gene, encoding P-type transporting ATPase. We performed genetic analysis three unrelated patients from...

10.1186/s12881-018-0619-4 article EN cc-by BMC Medical Genetics 2018-06-18

Vietnam is a developing country with tropical climate where infectious diseases, especially encephalitis are common. Every year, in National Hospital of Pediatrics from 200 to 300 patients hospitalized due encephalitis. A rapid assessment consciousness level importance treatment and prognosis for patients. Two scales usually used level, The Alert Verbal Painful Unresponsiveness (AVPU) scale the Glasgow Coma Scale (GCS). GCS score one most commonly methods. AVPU simple method consciousness....

10.21767/2573-0282.100029 article EN cc-by Pediatric Infectious Diseases Open Access 2016-01-01

Nghiên cứu nhằm đánh giá lợi ích của thành viên khi tham gia vào mô hình Hợp tác xã (HTX) nông nghiệp và đề xuất các giải pháp tăng số lượng thông qua việc cho viên. Thông thu thập tài liệu, điều tra thực tế với khảo sát 300 người dân là HTX Tân Bình, huyện Thanh tỉnh Đồng Tháp 12 cuộc phỏng vấn sâu lãnh đạo cũng như HTX. Các liệu được xử lý bằng phần mềm thống kê tả SPSS, kết quả nghiên đã chỉ ra những do chính mà là: Mua vật tư thấp (91,3%), Cải thiện kiện sản xuất, làm (85,7%) mục đích để...

10.62985/j.huit_ojs.vol24.no1.29 article VI Tạp chí Khoa học Đại học Công Thương. 2024-04-28

Mục tiêu: Khảo sát mối liên hệ giữa tật khúc xạ và lé mắt tại Bệnh viện Mắt TP.HCM trong giai đoạn 2017 - 2018 từ đó xác định hiệu quả điều chỉnh đối với sự thay đổi độ trước sau chỉnh. Phương pháp: Nghiên cứu cắt ngang hồi trên 589 trẻ em 1 tháng tuổi đến 23 được thu thập số liệu Phòng khám 1/1/2017 1/1/2018. Kết quả: nhân ngoài có tỉ lệ cận thị 38%; bệnh viễn cao 53%; đứng chưa phân biệt rõ 87,5% 8 trường hợp khảo (p < 0,001). Đối các ngoài, gần trung bình kính ở mức 28,14 ± 9,22Δ, giảm...

10.52163/yhc.v65icd8.1468 article VI Tạp chí Y học Cộng đồng 2024-09-09

Aims & Objectives: Younger age and higher leukocyte counts are associated with mortality in children pertussis who require mechanical ventilation previous studies. However, the majority were studied developed countries we do not know whether these findings applicable to developing countries. Methods A retrospective observational study was carried out a tertiary PICU Vietnam. Children under 24 months of required due from 2015 2017 enrolled. Pertussis diagnosed by PCR. Age, gender, symptoms,...

10.1097/01.pcc.0000538140.22528.f5 article EN Pediatric Critical Care Medicine 2018-05-31

Trong bài báo này, các tác giả xây dựng lời giải tích phân ứng xử uốn của dầm Timoshenko bằng vật liệu FGM xốp có liên kết đàn hồi ở hai đầu dầm. Ba quy luật bố lỗ rỗng được xem xét bao gồm: đều, đối xứng và bất xứng. Hệ trục tọa độ gắn với mặt trung hòa sử dụng nhằm đơn giản hóa quan hệ nội lực-chuyển vị. phương trình cân điều kiện biên cho thiết lập trên cơ sở nguyên lý biến phân. Các quả kiểm chứng đã trong tài liệu, đó tưởng thông là những trường hợp đặc biệt thu được. Ảnh hưởng tham số...

10.31814/stce.huce(nuce)2022-16(3v)-07 article VI Journal of Science and Technology in Civil Engineering (JSTCE) - HUCE 2022-07-29

Abstract The evolution of influenza viruses is fundamentally shaped by within-host processes. However, the evolutionary dynamics remain incompletely understood, in part because most studies have focused on virus diversity infections otherwise healthy adults based single timepoint data. Here, we analysed 82 longitudinally-sampled individuals, mostly young children, infected with A/H3N2 or A/H1N1pdm09 between 2007 and 2009. For during 2009 pandemic, nonsynonymous changes were common early...

10.1101/2021.03.20.436248 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2021-03-20

Background and objective Vietnam is the easternmost country on Indochina Peninsula in Southeast Asia. With an estimated 90 million inhabitants as of 2013, it world’s 13th-most-populous country, eighth-most-populous Asian country. Congenital anomalies accounted about 22% causes deaths children under-5 [2010]. The first service for IEMs was set up at Northern referral center Pediatrics-National Hospital Pediatrics, Hanoi (NHP) 2004 officially. NHP provides services to population North Vietnam...

10.3978/j.issn.2305-5839.2015.ab031 article EN Annals of Translational Medicine 2015-05-09
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