A5087745860- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Long-Term Effects of COVID-19
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Intensive Care Unit Cognitive Disorders
- Clinical Nutrition and Gastroenterology
- Chronic Obstructive Pulmonary Disease (COPD) Research
- COVID-19 Clinical Research Studies
- Electrolyte and hormonal disorders
- Hemodynamic Monitoring and Therapy
- Ultrasound in Clinical Applications
- Renal function and acid-base balance
- Nutrition and Health in Aging
- Tuberculosis Research and Epidemiology
- Diagnosis and treatment of tuberculosis
- Palliative Care and End-of-Life Issues
- Family and Patient Care in Intensive Care Units
- Mycobacterium research and diagnosis
- Blood Coagulation and Thrombosis Mechanisms
- Acute Ischemic Stroke Management
- Antibiotics Pharmacokinetics and Efficacy
- Blood properties and coagulation
- Airway Management and Intubation Techniques
- Antibiotic Use and Resistance
- COVID-19 epidemiological studies
Sotiria General Hospital
2013-2024
National and Kapodistrian University of Athens
2008-2024
The University of Queensland
2014
The pneumonia of COVID-19 illness has often a subtle initial presentation making mandatory the use biomarkers for evaluation severity and prediction final patient disposition. We evaluated hydrogen sulfide (H2S) outcome pneumonia.We studied 74 patients with COVID-19. Clinical data were collected, survival predictors calculated. Blood was collected within 24 h after admission (day 1) on day 7. H2S measured in sera by monobromobimane derivation followed high-performance liquid chromatography...
On 18 April 2014, a case of Middle East Respiratory Syndrome coronavirus (MERS-CoV) infection was laboratory confirmed in Athens, Greece patient returning from Jeddah, Saudi Arabia. Main symptoms upon initial presentation were protracted fever and diarrhoea, during hospitalisation he developed bilateral pneumonia his condition worsened. During 14 days prior to onset illness, had extensive contact with the healthcare environment Jeddah. Contact tracing revealed 73 contacts, no secondary cases...
Rationale: Due to effects of aging on the respiratory system, it is conceivable that association between driving pressure and mortality depends age. Objective: We endeavored evaluate whether patients with acute distress syndrome (ARDS) varies across adult lifespan, hypothesizing stronger in older, including very old (≥80 years), patients. Methods: performed a secondary analysis individual patient-level data from seven ARDS Network PETAL randomized controlled trials ("ARDSNet cohort"). tested...
Abstract Objective The thrombomodulin/protein C and VWF / ADAMTS ‐13 pathways are disturbed in sepsis have been implicated the coagulation disorders that characterize septic syndrome. We aimed to assess variation of these endothelial parameters during their putative association with outcome, critically ill, patients. Methods monitored 34 patients, 23 whom improved (group A) while 11 deteriorated B). assessed levels, activity, soluble thrombomodulin, protein activity upon admission ICU (time...
Stewart's approach is known to have better diagnostic accuracy for the identification of metabolic acid-base disturbances compared traditional methods based either on plasma bicarbonate concentration ([HCO3-]) and anion gap (AG) or base excess/deficit (BE). This study aimed identify disorders using approaches in critically ill COVID-19 patients admitted ICU, recognize potential hidden abnormalities assess prognostic value these patient outcome. was a single-center retrospective study, which...
1. Laursen CB, Clive A, Hallifax R, et al. European Respiratory Society statement on thoracic ultrasound. Eur Respir J. 2021;57(3):2001519. doi:10.1183/13993003.01519-2020. CrossRef Google Scholar
Objective . To clarify whether time lapsing from advent of fever as a first sign sepsis may be indicative the potency monocytes for release pro‐ and anti‐inflammatory mediators. Methods Monocytes were isolated blood 51 septic patients 9 healthy donors. incubated in absence presence patients′ serum concentrations tumour necrosis factor‐alpha (TNF α ), interleukin (IL)‐6, IL‐10, malondialdehyde (MDA) estimated supernatants. Patients divided into three groups: group A: <12 hours; B: 12–24...
Background: The concept of buffering generally refers to the ability a system/organism withstand attempted changes. For acid-base balance in particular, it is body’s limit pH aberrations when factors that potentially affect change. Buffering vital for maintaining homeostasis an organism. present study was undertaken order investigate probable capacity changes septic patients. Materials and methods: This prospective cohort included 113 ICU patients (96 17 critically-ill non-septic/controls)....
<b>Introduction:</b> Lung ultrasound (LUS) has emerged as a promising tool for the assessment of patients with respiratory failure in intensive care unit (ICU). A caveat wide implementation LUS is its operator-dependency. <b>Aims and Objectives:</b> To assess utility real-life conditions. <b>Methods:</b> The multicentre Greek RECUP-19 database was used that prospectively follows COVID-19 pneumonia hospitalized ICU. performed part clinical evaluation upon admission. Six regions (upper/lower...