A5032141338- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Respiratory Support and Mechanisms
- SARS-CoV-2 and COVID-19 Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Lung Cancer Diagnosis and Treatment
- Intensive Care Unit Cognitive Disorders
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Antifungal resistance and susceptibility
- Airway Management and Intubation Techniques
- Tracheal and airway disorders
- Sepsis Diagnosis and Treatment
- COVID-19 and healthcare impacts
- Esophageal and GI Pathology
- Pleural and Pulmonary Diseases
- Esophageal Cancer Research and Treatment
- Inflammatory Biomarkers in Disease Prognosis
- Child Abuse and Trauma
- Obstructive Sleep Apnea Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Sexuality, Behavior, and Technology
- Nosocomial Infections in ICU
- Salivary Gland Tumors Diagnosis and Treatment
- Historical Astronomy and Related Studies
- Venous Thromboembolism Diagnosis and Management
National and Kapodistrian University of Athens
2016-2025
Sotiria General Hospital
2020-2025
Respiratory Clinical Trials
2023
Panteion University
2017
Panagiotis & Aglaia Kyriakou Children's Hospital
2017
Democritus University of Thrace
2017
During the current pandemic, we witnessed a rise of post-intubation tracheal stenosis (PITS) in patients intubated due to COVID-19. We prospectively analyzed data from referred our institution during last 18 months for severe symptomatic upper airway complications. Interdisciplinary bronchoscopic and/or surgical management was offered. Twenty-three with PITS tracheoesophageal fistulae were included. They had undergone 31.85 (±22.7) days ICU hospitalization and 17.35 (±7.4) intubation....
Background: COVID-19-associated fungal infections seem to be a concerning issue. The aim of this study was assess the incidence infections, possible risk factors, and their effect on outcomes critically ill patients with COVID-19. Methods: A retrospective observational conducted in COVID-19 ICU First Respiratory Department National Kapodistrian University Athens Sotiria Chest Diseases Hospital between 27 August 2020 10 November 2021. Results: Here, 178 were included study. Nineteen (10.7%)...
Coronavirus disease 2019 (COVID-19) has been a pandemic since 2020, and depending on the SARS-CoV-2 mutation, different waves have observed. The aim of this study was to compare baseline characteristics patients in two phases evaluate possible predictors mortality.This is retrospective multicenter observational that included with COVID-19 4 centers Greece. Patients were divided into groups period during which they infected Delta Omicron variant predominance.A total 979 (433 Delta, 546...
The impact of severe infection from COVID-19 and the resulting need for life support in an ICU environment is a fact that caused immense pressure healthcare systems around globe. Accordingly, elderly people faced multiple challenges, especially after admission to ICU. On this basis, we performed study assess age on mortality critically ill patients. In retrospective study, collected data 300 patients who were hospitalized Greek respiratory hospital. We split into two groups using threshold...
Abstract A central paradigm of immunity is that interferon (IFN) mediated antiviral responses precede the pro-inflammatory ones, optimizing host protection and minimizing collateral damage 1,2 . Here, we report for COVID-19 this does not apply. By investigating temporal IFN inflammatory cytokine patterns in 32 patients hospitalized pneumonia longitudinally followed development respiratory failure death, reveal IFN-λ type I production both diminished delayed, induced only a fraction as they...
Data on COVID-19 mortality among patients in intensive care units (ICUs) from Eastern and/or Southern European countries, including Greece, are limited. The purpose of this study was to evaluate the ICU trends critically ill during first two years pandemic Greece and further investigate if certain patients' clinical characteristics contributed outcome. We conducted a multi-center retrospective observational five large university hospitals between February 2020 January 2022. All adult with...
Introduction Despite many technological advances, the diagnostic yield of bronchoscopic peripheral lung nodule analysis remains limited due to frequent mispositioning. Needle-based confocal laser endomicroscopy (nCLE) enables real-time microscopic feedback on needle positioning, potentially improving sampling location and yield. Previous studies have defined validated nCLE criteria for malignancy, airway parenchyma. Larger demonstrating effect are lacking. We aim investigate if nCLE-imaging...
Treatment of interstitial lung diseases (ILDs) other than idiopathic pulmonary fibrosis (IPF) often includes systemic corticosteroids. Use steroid-sparing agents is amenable to avoid potential side effects.Functional indices and high-resolution computed tomography (HRCT) patterns patients with non-IPF ILDs receiving mycophenolate mofetil (MMF) a minimum follow-up 1 year were analyzed. Two independent radiologists machine learning software system (Imbio 1.4.2.) evaluated HRCT...
Although several studies have been launched towards the prediction of risk factors for mortality and admission in intensive care unit (ICU) COVID-19, none them focuses on development explainable AI models to define an ICU scoring index using dynamically associated biological markers.
Stewart's approach is known to have better diagnostic accuracy for the identification of metabolic acid-base disturbances compared traditional methods based either on plasma bicarbonate concentration ([HCO3-]) and anion gap (AG) or base excess/deficit (BE). This study aimed identify disorders using approaches in critically ill COVID-19 patients admitted ICU, recognize potential hidden abnormalities assess prognostic value these patient outcome. was a single-center retrospective study, which...
Dreams preoccupied the Greek and Roman world in antiquity, therefore they had a prominent role social, philosophical, religious, historical political life of those times. They were considered as omens prophetic signs future events private public life, that was particularly accentuated when elements actions which took place plot dreams associated directly or indirectly with real events. This is why it important to use them divination, helped growth superstition folklore believes. Medicine...
Severe COVID-19 is characterized by excessive inflammation leading to the development of pneumonia and acute respiratory distress syndrome. Bioactive lipid mediators (LMs) derived from ω6 ω3 polyunsaturated fatty acids are central regulation inflammation, controlling both its initiation resolution. Still, their role in remains underexplored. By employing a holistic approach involving analysis white blood cell transcriptomes, targeted lipidomics, cytokine immune profiling, across spectrum...
Asthma is a complex inflammatory airway disease affecting significant global population, spanning from childhood through adulthood. Despite advances in treatment modalities, subset of patients, approximately 10%, grapple with severe asthma, characterized by increased healthcare utilization and diminished quality life. Tezepelumab, monoclonal antibody targeting thymic stromal lymphopoietin (TSLP), offers promising therapeutic potential. TSLP protein released variety cells, predominance...
1. Bousquet J, Mantzouranis E, Cruz AA, et al. Uniform definition of asthma severity, control, and exacerbations: Document presented for the World Health Organization Consultation on Severe Asthma. J Allergy Clin Immunol. 2010;126(5):926-938. doi:10.1016/j.jaci.2010.07.019 CrossRef Google Scholar
Homosexuality and pedophilia in ancient Greece greatly concerned many researchers who were mainly interested highlighting the social aspect of this phenomenon Greek society. An important source on subject was paintings a man his lover attic black red figured pottery, up to end 5th century BC. Another main information that derived from texts literature, especially poetry. not only referring relationships between males, but it also manifested lesbian love. It is believed Homeric world...
Background: Pulmonary Artery Sarcomas are the rarest and most aggressive vascular tumors. Their accurate diagnosis is challenging due to lack of specific symptoms clinical manifestations they often initially misdiagnosed managed as chronic pulmonary thromboembolic disease until an alternate suspected based on response anticoagulants. Proper management thus delayed histological confirmation. Moreover, consensus regarding their treatment further contributes reported high mortality [1]. Case...