A5057072599- Anesthesia and Pain Management
- Cardiac, Anesthesia and Surgical Outcomes
- Spine and Intervertebral Disc Pathology
- Intraocular Surgery and Lenses
- Cardiovascular Issues in Pregnancy
- Nausea and vomiting management
- Anesthesia and Sedative Agents
- Spinal Hematomas and Complications
- Renal and Vascular Pathologies
- Innovations in Medical Education
- Cancer-related gene regulation
- Simulation-Based Education in Healthcare
- Anesthesia and Neurotoxicity Research
- Stress Responses and Cortisol
- Glaucoma and retinal disorders
- Ubiquitin and proteasome pathways
- Hemodynamic Monitoring and Therapy
- Liver Disease Diagnosis and Treatment
- Dental Anxiety and Anesthesia Techniques
- Epigenetics and DNA Methylation
- Cardiac Ischemia and Reperfusion
- Study of Mite Species
- High Altitude and Hypoxia
- Pain Management and Opioid Use
- Peptidase Inhibition and Analysis
Zunyi Medical University
2024-2025
First Affiliated Hospital of Wannan Medical College
2013-2024
Shenzhen University Health Science Center
2023
Wannan Medical College
2013-2022
Nanjing Medical University
2022
Women's Hospital
2022
Shenzhen Second People's Hospital
2021
Jinan University
2021
Shenzhen University
2021
Sun Yat-sen University
2001-2020
For patients with bilateral age-related cataracts, sequential phacoemulsification and intraocular lens implantation is a common treatment. However, it remains unclear whether surgery on the first eye has an impact second eye, as current research results are inconsistent. This study will explore one affects non-operated through aqueous humor cytokines metabolomic analyses in eye. A rabbit model of unilateral was established. The experimental group consisted 15 rabbits undergoing this...
To evaluate patient pain and discomfort following oculoplastic surgery performed under general anesthesia to assess key factors associated with postoperative discomfort.A prospective observational cohort study was conducted among 212 consecutive patients who underwent anesthesia. The were assessed according quantified levels of postoperatively. Analgesic requests recorded, responses statistically analyzed.Pain after reported by 32.1% 28.3% the patients, respectively; 2.8% requested analgesic...
Oncogenic KRAS mutations are a key driver for initiation and progression in non-small cell lung cancer (NSCLC). However, how post-translational modifications (PTMs) of KRAS, especially methylation, modify activity remain largely unclear. Here, we show that SET domain containing histone lysine methyltransferase 7 (SETD7) interacts with methylates at lysines 182 184. SETD7-mediated methylation leads to degradation attenuation the RAS/MEK/ERK signaling cascade, endowing SETD7 potent...
An outbreak of urinary stones related to consumption melamine-tainted milk products (MTMP) occurred in China 2008. The aim the present study was evaluate such children identify their clinical features and risk factors.Renal ultrasound performed for 7328 who presented a Sichuan teaching hospital between 13 September 15 October 2008 due concern stones. Clinical data, family information, feeding history were analyzed.Of children, 189 (2.58%) had findings stones, 51 admitted. Age (mean ± SD)...
At present, there is no noninvasive biomarker of renal fibrosis. The potential diagnostic value urinary exosome-derived circRNAs from glomerular disease patients for fibrosis still uncertain. Here, we first detected the expression hsa_circ_0008925 in TGF-β1-cultured HK-2 cell-derived exosomes. Secondly, collected urine samples 95 biopsy-proven and 34 healthy controls. was analyzed, correlation with function pathological changes calculated. receiver operating characteristic (ROC) curve...
Background Azithromycin is an antibacterial and anti-inflammatory drug widely used for the treatment of various diseases, including those caused by atypical pathogens, bacterial or viral infections, chronic sinusitis, bronchial asthma, particularly in pediatric patients. However, concerns have emerged regarding its hepatotoxicity precise mechanism action remains unclear.
Background: The purpose of this study was to investigate effect cerebral oxygen saturation (SCTO2) on postoperative nausea and vomiting (PONV) in female patients who underwent laparoscopic surgery. Methods: This included 90 surgery (60 cases gynecological operations 30 gallbladder operations). All were allocated into 3 groups each: group A (gynecological surgery), B with mannitol treatment) C (laparoscopic cholecystectomy surgery). Perioperative SCTO2, mean blood flow velocity vertebral...
The aim of this study was to evaluate postoperative discomfort in patients undergoing ambulatory strabismus under general anesthesia, and identify risk factors associated with the discomfort.A cross-sectional conducted among 210 consecutive anesthesia. Postoperative including nausea, vomiting, dizziness, headache recorded quantified. Univariable multivariable logistic regression were performed detect discomfort.Of participants, 199 (94.76%) experienced mild after surgery 31 (14.76%), 11...
The purpose of this study was to determine whether ticagrelor, a classic anti-platelet drug, has therapeutic effect on sepsis-induced myocardial injury.The C57BL6J mice received oral ticagrelor (10, 25 and 50 mg/kg) for seven days after which cecum ligation puncture (CLP) were performed. An adenosine-receptor antagonist (CGS15943) administered two hours before CLP. After 24 h, cardiac function measured using echocardiography, then the heart blood collected. Hematoxylin eosin (HE) staining...
Purpose: This study aimed to investigate postoperative analgesia achieved with intraoperative administration of intravenous flurbiprofen axetil and nalbuphine in patients undergoing orbital decompression. Methods: Sixty-three decompression under general anesthesia at the Zhongshan Ophthalmic Center Sun Yat-sen University (Guangzhou, China) were randomly allocated into one following three groups (1:1:1): 100 mg (Group 1); 0.1 mg/kg 2); or combined 3). The primary end point was mean pain...
Background: Phenylephrine and atropine can cause serious adverse effects when applied in combination. We investigated the effect of phenylephrine eye drops combined with intravenous on cardiovascular system patients under general anesthesia undergoing intraocular surgery. Methods: The drugs were observed through clinical study. Thirteen surgery this study; all injected intravenously due to oculocardiac reflex during To study combination drugs, an vivo was performed rats. Seventy-two standard...
Purpose: To prospectively explore the incidence and risk factors of moderate to severe pain after primary secondary orbital implantation following evisceration or enucleation surgery. Methods: One hundred eighteen patients under general anesthesia for were enrolled in this study. In 91 patients, followed evisceration, 27 was previous Medical interventions all participants by standardized surgical, anesthetic, analgesic protocols. Postoperative (POP) intensity quantified an 11-point numerical...
<title>Abstract</title> <bold>Background: </bold>For patients with bilateral age-related cataracts, sequential phacoemulsification and intraocular lens implantation is a common treatment. However, it remains unclear whether surgery on the first eye affects outcome of second eye, as current research results are inconsistent. This study will explore one non-operated by analyzing changes in aqueous humor biomarkers metabolomics eye. <bold>Methods: </bold>A rabbit model unilateral was...
Objective: To explore the predictive value of gastric antral cross-sectional area (CSA) in occurrence postoperative nausea and vomiting (PONV) by analysing association between CSA measured ultrasound frequency PONV after laparoscopic cholecystectomy.Study Design: Observational study.
The anatomical dimensions of the lumbar dural sac determine sensory block level spinal anesthesia; however, whether they show same predictive value during continuous epidural anesthesia (CEA) remains undetermined. We designed present study to verify efficacy in predicting labor analgesia.A total 122 parturients with singleton pregnancies requesting analgesia were included this study. diameter (DSD), length (DSL), surface area (DSA), and volume (DSV) measured an ultrasound color Doppler...
Ephedrine increased blood pressure due to the contractile properties of resistance vessels. Excessive contraction uterine arteries might cause fetal distress. This study was determine diameter artery female New Zealand rabbits after administration different doses ephedrine using CT.Thirty-two were randomly divided into a control group (Group C), low dosage L), medium M) and high H). Normal saline corresponding human dose 7.5, 15 30 mg injected respectively. The marginal ear diameters...
Objective To investigate good teaching models for anesthesiology interns to improve clinical quality.Methods 58 students majored in from grade 2006 2008 were divided into three groups.15 took flow model,18 fixed model and 25 stages model.The effect was evaluated by comparing students' theories skills achievement,evaluating effects through questionnaires,and observing anesthesia-related medical errors incidences among groups.Results Students of group significantly better than other two groups...