- Antibiotic Resistance in Bacteria
- Salmonella and Campylobacter epidemiology
- Bacterial Identification and Susceptibility Testing
- Rabies epidemiology and control
- Pharmaceutical and Antibiotic Environmental Impacts
- Viral Infections and Vectors
- Microbial infections and disease research
- Antimicrobial Resistance in Staphylococcus
- Animal Disease Management and Epidemiology
- Viral gastroenteritis research and epidemiology
- Virology and Viral Diseases
- Parasitic Infections and Diagnostics
- Influenza Virus Research Studies
- Clostridium difficile and Clostridium perfringens research
- Escherichia coli research studies
- Aquaculture disease management and microbiota
- Animal Virus Infections Studies
- Bacteriophages and microbial interactions
- Mycobacterium research and diagnosis
- Virus-based gene therapy research
- Antibiotics Pharmacokinetics and Efficacy
- Vibrio bacteria research studies
- Herpesvirus Infections and Treatments
- Child Nutrition and Water Access
- Respiratory viral infections research
Murdoch University
2016-2025
Department of Primary Industries and Regional Development
2021-2023
Harry Butler Institute
2023
Agriculture and Food
2013-2015
Toowoomba Hospital
2014
Department of Agriculture and Food Western Australia
2007-2011
Government of Western Australia
2007-2011
Stanford University
1934
Streptococcus suis is a swine pathogen and zoonotic agent afflicting people in close contact with infected pigs or pork meat. Sporadic cases of human infections have been reported worldwide. In addition, S. outbreaks emerged Asia, making this bacterium primary health concern part the globe. pigs, disease results decreased performance increased mortality, which significant economic impact on production Facing new regulations preventive use antimicrobials livestock lack effective vaccines,...
Abstract Objectives Antimicrobial resistance (AMR) to critically important antimicrobials (CIAs) amongst Gram-negative bacteria can feasibly be transferred wildlife, humans and domestic animals. This study investigated the ecology, epidemiology origins of CIA-resistant Escherichia coli carried by Australian silver gulls (Chroicocephalus novaehollandiae), a gregarious avian wildlife species that is common inhabitant coastal areas with high levels human contact. Methods Sampling locations were...
Carbapenem-resistant Enterobacteriaceae (CRE) are a pressing public health issue due to limited therapeutic options treat such infections. CREs have been predominantly isolated from humans and environmental samples they rarely reported among companion animals. In this study we report on the isolation plasmid characterization of carbapenemase (IMP-4) producing Salmonella enterica Typhimurium animal. Carbapenemase-producing S. carrying blaIMP-4 was identified systemically unwell (index) cat...
In a structured survey of all major chicken-meat producers in Australia, we investigated the antimicrobial resistance (AMR) and genomic characteristics
Escherichia coli sequence types 131 (ST131) and 1193 are multidrug-resistant extraintestinal pathogens that have recently spread epidemically among humans occasionally isolated from companion animals. This study characterized a nationwide collection of fluoroquinolone-resistant (FQ R ) E. isolates infections in Australian cats dogs. For this, 59 cat dog FQ clinical (representing 6.9% an 855-isolate collection) underwent PCR-based phylotyping whole-genome sequencing (WGS). Isolates...
Abstract This study investigated the ecology, epidemiology and plasmid characteristics of extended-spectrum cephalosporin (ESC)-resistant E. coli in healthy pigs over a period 4 years (2013–2016) following withdrawal ESCs. High carriage rates ESC-resistant were demonstrated 2013 (86.6%) 2014 (83.3%), compared to 2015 (22%) 2016 (8.5%). ESC resistance identified among isolates was attributed an IncI1 ST-3 (pCTXM1-MU2) encoding blaCTXM-1. Genomic characterisation selected (n = 61) movement...
This study investigated the frequency of antimicrobial non-susceptibility (defined as isolates with minimum inhibitory concentrations above CLSI susceptible clinical breakpoint) among E. coli and Salmonella spp. isolated from healthy Australian finisher pigs. (n = 201) 69) were cecal contents slaughter-age pigs, originating 19 farms distributed throughout Australia during July-December 2015. Isolates underwent concentration (MIC) susceptibility testing to 11 antimicrobials. The highest...
Background Avian influenza viruses (AIVs) are found worldwide in numerous bird species, causing significant disease gallinaceous poultry and occasionally other species. Surveillance of wild reservoirs provides an opportunity to add the understanding epidemiology AIVs. Methods This study examined key findings from National Influenza Wild Bird Program over a 5‐year period (July 2007–June 2012), main source information on AIVs circulating Australia. Results The overall proportion birds that...
The World Health Organisation has defined "highest priority critically important antimicrobials" (CIAs) as those requiring the greatest control during food production. Evidence demonstrating that restricted antimicrobial usage prevents emergence of resistance to CIA's amongst pathogenic and commensal organisms on a production system-wide scale would strengthen international efforts (AMR). Therefore, in designed survey all major chicken-meat producers Australia, we investigated phenotypic AMR...
The lack of awareness about dog-bite related rabies in the rural population developing countries, including India, is a major impediment to controlling incidence disease humans. A survey 127 residents was undertaken Shirsuphal village western India using structured questionnaire assess influence demographic and pet/livestock owning characteristics on knowledge, attitudes practices respondents towards free roaming dogs (FRD). Multivariable logistic regression models were constructed knowledge...
Knowledge of etiology causes diarrheal illness is essential for development and implementation public health measures to prevent control this disease syndrome. There are few published studies examining diarrhea in children aged <5 years Iraq. This study aims investigate the occurrences epidemiology selected bacterial (Salmonella spp. Campylobacter spp.), viral (adenovirus, norovirus GI GII, astrovirus), parasitic (Entamoeba Giardia spp.) agents stool samples from 155 child cases enrolled...
Canine rabies is endemic in urban India. A questionnaire was administered to 204 residents of the urbanised municipality Panchkula north India assess influence gender, age, family size, social status and dog ownership, over knowledge, attitudes practices (KAP) towards control free-roaming dogs (FRD) their locality. Bivariate analyses revealed significant knowledge gaps regarding crucial information on transmission rabies. Multivariable logistic regression models found that respondents with a...
Abstract Background Enterotoxigenic F4 E. coli (F4-ETEC) pose an economic threat to the swine industry through reduced growth, increased mortality and morbidity, costs associated with treatment. Prevention treatment of F4-ETEC often relies on antimicrobials; however, due antimicrobial resistance, use is being minimized, hence alternative control methods are needed. This study investigated effects postbiotics in form Lactobacillus acidophilus fermentation products (LFP) Saccharomyces...
A respiratory disease syndrome has been observed in large numbers of wild shingleback lizards (Tiliqua rugosa) admitted to wildlife care facilities the Perth metropolitan region Western Australia. Mortality rates are reportedly high without supportive treatment and care. Here we used next generation sequencing techniques screen affected unaffected individuals Kanyana Wildlife Rehabilitation Centre between April December 2015, with resultant discovery a novel nidovirus significantly...
We describe the evolutionary origins and antigenic properties of influenza A viruses isolated from two separate Australian swine populations 2012 to 2016, showing that these are distinct each other those globally. Whole-genome sequencing virus isolates revealed a high genotypic diversity had been generated exclusively through introduction establishment human circulated in past seasons. detected six reassortants with gene segments derived H1N1/H1N1pdm09 various H3N2 during periods since 1968....
The presence of unvaccinated free-roaming dogs (FRD) amidst human settlements is a major contributor to the high incidence rabies in countries where disease endemic, such as India. Estimating FRD population size crucial planning and evaluation interventions, mass immunisation, against rabies. Enumeration techniques for are resource intensive can vary from simple direct counts statistically complex capture-recapture primarily developed ecological studies. In this study we compared eight...