- Immunodeficiency and Autoimmune Disorders
- Blood disorders and treatments
- Inflammasome and immune disorders
- Food Allergy and Anaphylaxis Research
- Adolescent and Pediatric Healthcare
- Childhood Cancer Survivors' Quality of Life
- Spondyloarthritis Studies and Treatments
- HIV Research and Treatment
- Osteomyelitis and Bone Disorders Research
- Drug-Induced Adverse Reactions
- Eosinophilic Esophagitis
- Gout, Hyperuricemia, Uric Acid
- Mast cells and histamine
- Lymphoma Diagnosis and Treatment
- Vector-borne infectious diseases
- Dermatology and Skin Diseases
- Neutropenia and Cancer Infections
- HIV/AIDS drug development and treatment
- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Pneumocystis jirovecii pneumonia detection and treatment
- Eosinophilic Disorders and Syndromes
- Rabies epidemiology and control
- Celiac Disease Research and Management
- Cystic Fibrosis Research Advances
Hospital General Universitario Gregorio Marañón
2006-2025
Hospital Universitario Infanta Leonor
2012
Multiple Non-steroidal anti-inflammatory drugs (NSAID)-induced urticaria/angioedema is the most common manifestation of hypersensitivity reactions to NSAIDs. Diagnostic evaluation based on clinical history and a drug provocation test.To evaluate role in diagnosis multiple NSAID-induced urticaria/angioedema.We studied group patients with an unequivocal urticaria and/or angioedema after NSAID intake. Subjects had have at least two episodes cutaneous symptoms different COX-1 inhibitors. The was...
Abstract Background Due to the absence of curative treatments for inborn errors immunity (IEI), children born with IEI require long-term follow-up disease manifestations and related complications that occur over lifespan. Effective transition from pediatric adult services is known significantly improve adherence treatment outcomes. It currently not what are available young people in Europe. Objective To understand prevalence practice Europe IEI, encompassing both primary immunodeficiencies...
Atopic dermatitis (AD) has a high incidence in heart-transplant children, and the reason why there is more AD after transplantation still unknown. We conducted cross-sectional study comparing 11 non-AD age-matched to assess which immune alterations are related these patients. patients had been transplanted at younger age compared non-AD, indicating that transplant may be determinant onset of AD. The earlier thymectomy children favored presence differentiated phenotypes T cell compartment....
The transition from pediatric to adult care is a critical milestone in managing children, especially those with complex chronic conditions. It involves ensuring the patient and family adapt correctly new phase, maintaining continuity of ongoing treatments, establishing an appropriate follow-up plan specialists. Patients Inborn error immunity (IEI), formerly known as Primary Immune Disorders (PID) are part group disorders characterized by alterations proper functioning immune system;...
To evaluate the efficacy of colchicine therapy in pediatric patients with PFAPA syndrome who present an incomplete response to standard treatment or frequent episodes (an interval less than 14 days between two disease flares).A multicenter cohort study children diagnosed and treated was performed three separate hospitals located Spain. The clinical laboratory data were reviewed by accessing their medical records. Response evaluated after 12 months for frequency, duration, intensity...
Human immunodeficiency virus (HIV) infection causes a severe cellular immunodeficiency, which results in greater susceptibility to infectious, inflammatory and malignant conditions. Among these, pathologies of the skin seem be those most frequently observed HIV+ patients. However, there are few reports on how antiretroviral therapy affects disorders HIV-infected children.To study incidence prevalence cohort children, relation antiviral [nontreated, monotherapy, combined highly active...
Immunologic and hemato-oncologic disorders in the pediatric population represent an interrelated complex group of conditions whose approach, diagnosis, management could be difficult. Multidisciplinary teams have been proved beneficial treating such complexities.We conducted a retrospective observational study at tertiary hospital Madrid, Spain, which is immunology onco-hematology referral center. We included all patients multidisciplinary outpatient consultation, comprising working...
Chronic recurrent multifocal osteomyelitis (CRMO) is a rare idiopathic autoinflammatory bone disease characterised by noninfective inflammation of bones. Diagnostic approach challenging and requires exclusion other causes such as malignancies or infections. Nonsteroidal anti-inflammatory drugs (NSAIDs) corticosteroids are usually applied first-line therapy in CRMO patients; however, some cases require more intensive with second-line agents to control activity. We hereby describe the use...