- Metabolomics and Mass Spectrometry Studies
- Computational Drug Discovery Methods
- Vector-borne infectious diseases
- Enzyme Production and Characterization
- Enzyme Structure and Function
- Wheat and Barley Genetics and Pathology
- Insect and Pesticide Research
- Microbial Metabolic Engineering and Bioproduction
- Vibrio bacteria research studies
- Plant-Microbe Interactions and Immunity
- Antimicrobial Peptides and Activities
- Neurobiology and Insect Physiology Research
- Thyroid Cancer Diagnosis and Treatment
- Viral Infections and Vectors
- Bacillus and Francisella bacterial research
- Plant Pathogens and Fungal Diseases
- Yersinia bacterium, plague, ectoparasites research
- Biochemical and Structural Characterization
- Plant Pathogens and Resistance
- Plant Molecular Biology Research
- Thyroid Disorders and Treatments
- Insect symbiosis and bacterial influences
- Insect-Plant Interactions and Control
- Reservoir Engineering and Simulation Methods
- Microbial Natural Products and Biosynthesis
Henan University
2020-2025
Henan Agricultural University
2016-2024
Tianjin Medical University General Hospital
2024
Epic Sciences (United States)
2023
Nanjing University of Aeronautics and Astronautics
2023
National Engineering Research Center for Wheat
2022-2023
Institute of Microbiology
2020-2022
Hebei Normal University
2008-2021
State Key Laboratory of Cotton Biology
2020
Chinese Academy of Sciences
2014-2019
Juvenile hormone (JH) acts as a gonadotrophic stimulating insect vitellogenesis and oogenesis. Paracellular transport of yolk proteins through intercellular channels (patency) in the follicular epithelium is developmentally regulated evolutionarily conserved process during vitellogenesis. However, mechanisms underlying patency opening are poorly understood. Using migratory locust Locusta migratoria model system, we report here that JH-regulated remodeling zonula adherens (ZA), belt-like...
Objective This retrospective study aims to evaluate the therapeutic effect of varying dosages adjuvant radioactive iodine (RAI) therapy on intermediate-risk papillary thyroid carcinoma (PTC) patients. Methods involved a total 427 PTC patients, out which 202 received 3.7GBq dosage RAI, and 225 5.55GBq dosage. The evaluation assessing outcomes, number treatment cycles, successful remnant ablation rates in both dose groups, six months post-adjuvant RAI therapy. Univariate multivariate logistic...
Summary Powdery mildew disease, elicited by the obligate fungal pathogen Blumeria graminis f.sp. tritici ( Bgt ), causes widespread yield losses in global wheat crop. However, molecular mechanisms governing defense to are still not well understood. Here we found that TuACO3 , encoding 1‐aminocyclopropane‐1‐carboxylic acid (ACC) oxidase functioning ethylene (ET) biosynthesis, was induced infection of einkorn Triticum urartu which accompanied increased ET content. Silencing decreased...
Abstract Powdery mildew disease caused by Blumeria graminis f. sp. tritici ( Bgt ) inflicts severe economic losses in wheat crops. A systematic understanding of the molecular mechanisms involved resistance to is essential for effectively controlling disease. Here, using diploid Triticum urartu as a host, genes regulated immune (IM) and hypersensitive reaction (HR) responses were investigated through transcriptome sequencing. Four gene coexpression networks (GCNs) developed transcriptomic...
Adipokinetic hormones (AKHs), the neurohormones synthesized in insect corpora cardiaca are known to mobilize lipids and carbohydrates for energy-consuming activities including reproduction. However, both inhibitory stimulatory effects of AKHs on reproduction have been reported, underlying mechanisms remain elusive. Using migratory locust, Locusta migratoria, as a model system, we report here that expressed response rhythmic diel change, AKH III expression increases markedly at photophase....
Viruses often usurp host machineries for their amplification, but it remains unclear if hosts may subvert virus proteins to regulate viral proliferation. Here, we show that the 17K protein, an important virulence factor conserved in barley yellow dwarf viruses (BYDVs) and related poleroviruses, is phosphorylated by GRIK1-SnRK1 kinases, with (P17K) capable of enhancing abundance virus-derived small interfering RNAs (vsiRNAs) thus antiviral RNAi. Furthermore, P17K interacts RNA-degrading...
Aphids, the destructive insect pests in agriculture, horticulture and forestry, are capable of reproducing asexually sexually upon environmental change. However, molecular basis aphid reproductive mode switch remains an enigma. Here we report a comparative analysis differential gene expression profiling among parthenogenetic females, gynoparae sexual females cotton Aphis gossypii, using RNA-seq approach with next-generation sequencing platforms, followed by RT-qPCR. At cutoff criteria fold...
Summary The LRK10‐like receptor kinases (LRK10L‐RLKs) are ubiquitously present in higher plants, but knowledge of their expression and function is still limited. Here, we report functional analysis TtdLRK10L‐1, a typical LRK10L‐RLK durum wheat ( Triticum turgidum L. ssp. ). introns TtdLRK10L‐1 contained multiple kinds predicted cis ‐elements. To investigate the potential effect these ‐elements on function, two types transgenic lines were prepared, which expressed GFP‐tagged protein...
Vibrio fluvialis is a food-borne pathogen with epidemic potential that causes cholera-like acute gastroenteritis and sometimes extraintestinal infections in humans. However, research on its genetic diversity pathogenicity-related elements based whole genome sequences lacking. In this study, we collected sequenced 130 strains of V. from 14 provinces China, also determined the susceptibility 35 to 30 different antibiotics. Combined 52 publicly available genomes, inferred population structure...
Abstract G protein‐coupled receptors (GPCRs), a superfamily of integral transmembrane proteins regulate variety physiological processes in insects. Juvenile hormone (JH) is known to stimulate Vitellogenin (Vg) synthesis the fat body, secretion into hemolymph and uptake by developing oocytes. However, role GPCRs JH‐dependent insect vitellogenesis oocyte maturation remains elusive. In present study, we performed transcriptomic analysis RNA interference (RNAi) screening vitellogenic females...
Studies on the seasonal abundance and activity of larvae, nymphs adults Dermacentor silvarum (Ixodida: Ixodidae), both off host, were carried out over a 2-year period from February 2008 to January 2010 in northern China. During study period, feeding ticks removed weekly domestic sheep free-living collected by flag-dragging four different habitat types. Rodents captured inspected for immature June September 2008. The results this suggest that mainly reside shrubs complete only one generation...