Edoardo Puglielli
A5073558639- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Spine and Intervertebral Disc Pathology
- Stroke Rehabilitation and Recovery
- Musculoskeletal pain and rehabilitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracranial Aneurysms: Treatment and Complications
- Advanced MRI Techniques and Applications
- Fetal and Pediatric Neurological Disorders
- Peripheral Artery Disease Management
- Anesthesia and Pain Management
- Meningioma and schwannoma management
- Educational and Social Studies
- Anarchism and Radical Politics
- Spinal Fractures and Fixation Techniques
- Brain Tumor Detection and Classification
- Glioma Diagnosis and Treatment
- Spinal Cord Injury Research
- Inflammatory Myopathies and Dermatomyositis
- Spinal Hematomas and Complications
- Cancer Diagnosis and Treatment
- Retinal Development and Disorders
- Nitric Oxide and Endothelin Effects
- Gastrointestinal Bleeding Diagnosis and Treatment
University of Teramo
2022-2025
Roma Tre University
2019
University of L'Aquila
2001-2005
San Salvatore Hospital
2003
Background and Purpose: As numerous questions remain about the best anesthetic strategy during thrombectomy, we assessed functional radiological outcomes in stroke patients treated with thrombectomy presence of general anesthesia (GA) versus conscious sedation (CS) local (LA). Methods: We conducted a cohort study on prospectively collected data from 4429 enrolled Italian Registry Endovascular Treatment Acute Stroke. Results: GA was used 2013 patients, CS 1285 LA 1131 patients. The rates...
Background and Purpose— As a reliable scoring system to detect the risk of symptomatic intracerebral hemorrhage after thrombectomy for ischemic stroke is not yet available, we developed nomogram predicting in patients with large vessel occlusion anterior circulation who received bridging intravenous thrombolysis (training set), validate model by using cohort treated direct (test set). Methods— We conducted study on prospectively collected data from 3714 enrolled IER (Italian Registry...
Background and Purpose: To evaluate outcome safety of endovascular treatment beyond 6 hours onset ischemic stroke due to large vessel occlusion in the anterior circulation, routine clinical practice. Methods: From Italian Registry Endovascular Thrombectomy, we extracted data patients treated for known hours. Additional inclusion criteria were prestroke modified Rankin Scale score ≤2 ASPECTS ≥6. Patients selected on individual basis by a combination CT perfusion mismatch (difference between...
There are limited data concerning procedure-related complications of endovascular thrombectomy for large vessel occlusion strokes.We evaluated the cumulative incidence, clinical relevance in terms increased disability and mortality, risk factors complications.From January 2011 to December 2017, 4799 patients were enrolled by 36 centers Italian Registry Endovascular Stroke Treatment. Data on demographic procedural characteristics, complications, outcome at three months prospectively...
The benefits and safety of mechanical thrombectomy (MT) in patients with prestroke disability, classified as modified Rankin Scale (mRS) score 3 to 4, anterior circulation stroke remain uncertain. This study aims evaluate these factors using data from the Italian Registry Endovascular Treatment Acute Stroke. We analyzed collected between 2015 2021, comparing functional outcomes (mRS), symptomatic intracerebral hemorrhage, recanalization rates (Thrombolysis Cerebral Infarction) at 90 days...
We sought to investigate whether there are gender differences in clinical outcome after stroke due large vessel occlusion (LVO) mechanical thrombectomy (EVT) a population of real-world patients.From the Italian Registry Endovascular Thrombectomy, we extracted and data patients treated for occlusion. compared safety outcomes men women who underwent EVT alone or combination with intravenous thrombolysis (IVT) total Propensity Score matched set.Among 3422 included study, 1801 (52.6%) were...
Background The applicability of the current models for predicting functional outcome after thrombectomy in strokes with large vessel occlusion (LVO) is affected by a moderate predictive performance. Aims We aimed to develop and validate nomogram pre- post-treatment factors prediction probability unfavorable patients anterior posterior LVO who received bridging therapy or direct <6 h stroke onset. Methods conducted cohort study on data collected prospectively Italian Endovascular Registry...
Introduction: Data on safety and efficacy of endovascular thrombectomy (EVT) for acute ischemic stroke in older patients are limited controversial, people aged 80 or were under-represented randomized trials. Our aim was to assess EVT effect ⩾80 at a nationwide level. Patients methods: The cohort included undergoing from the Italian Registry Endovascular Treatment Acute Stroke (IRETAS). priori divided into younger groups (<80 vs ⩾80). Primary outcome good functional (modified Rankin scale,...
The weight of outcome predictors in acute ischemic stroke (AIS) patients older than 60 years is not necessarily mirrored the younger population, posing question whether determinants specific for latter might vary. Very few data are available on young AIS receiving endovascular treatment (EVT).We analyzed aged between 16 and 55 from Italian Registry Endovascular Treatment Acute Stroke. We divided our population into <45 old 45 years. After testing differences groups terms 90-day modified...