A5100415684- Effects of Radiation Exposure
- Advanced MRI Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Advanced Neuroimaging Techniques and Applications
- MRI in cancer diagnosis
- Medical Imaging Techniques and Applications
- Immune Response and Inflammation
- Transplantation: Methods and Outcomes
- Immune Cell Function and Interaction
- Corneal surgery and disorders
- Coronary Interventions and Diagnostics
- Corneal Surgery and Treatments
- Epigenetics and DNA Methylation
- Food Quality and Safety Studies
- RNA modifications and cancer
- Glaucoma and retinal disorders
- Phytochemicals and Antioxidant Activities
- Knee injuries and reconstruction techniques
- Mechanical Circulatory Support Devices
- Polysaccharides and Plant Cell Walls
- Total Knee Arthroplasty Outcomes
- Cancer-related molecular mechanisms research
- Medical Image Segmentation Techniques
- Hydrogen's biological and therapeutic effects
- Diet, Metabolism, and Disease
Chinese PLA General Hospital
2017-2025
Affiliated Hospital of Hebei University
2023-2025
Peking University
2012-2024
Peking University Third Hospital
2012-2024
Wuhan Institute of Technology
2014-2024
Guang’anmen Hospital
2020-2024
Southern University of Science and Technology
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
1991-2024
Northern Jiangsu People's Hospital
2024
Yangzhou University
2024
Traditional Chinese medicine (TCM), an ancient system of alternative medicine, played active role in the prevention and control COVID-19 China. It improved clinical symptoms patients, reduced mortality rate, recovery effectively relieved operating pressure on national medical during critical conditions. In light current global pandemic, TCM-related measures might open up a new channel other countries regions. Here, we summarize that were widely used China, including TCM guidelines, Wuchang...
Positron emission tomography (PET) has been widely used in clinical diagnosis for diseases and disorders. To obtain high-quality PET images requires a standard-dose radionuclide (tracer) injection into the human body, which inevitably increases risk of radiation exposure. One possible solution to this problem is predict image from its low-dose counterpart corresponding multimodal magnetic resonance (MR) images. Inspired by success patch-based sparse representation (SR) super-resolution...
Positron emission tomography (PET) images are widely used in many clinical applications, such as tumor detection and brain disorder diagnosis. To obtain PET of diagnostic quality, a sufficient amount radioactive tracer has to be injected into living body, which will inevitably increase the risk radiation exposure. On other hand, if dose is considerably reduced, quality resulting would significantly degraded. It great interest estimate standard-dose (S-PET) image from low-dose one order...
<title>Abstract</title> Natural thymoquinone has been extensively used as a chemopreventive agent and shown potent anticarcinogenic activity against broad range of human malignancies. However, the underlying mechanisms involving signaling pathways are still not well studies. Therefore, this study is aimed to evaluate effects on increasing doxorubicin chemosensitivity via targeting P21 PI3K/AKT signaling. Caco-2 cells were treated with thymoquinone. MTT assay applied assess impact different...
Bladder cancer is a common malignant tumor of the urinary tract as well one most cancers worldwide. Therefore, study key molecular targets involved in bladder carcinogenesis and progression crucial for prognosis cancer. Our aims to investigate mechanism by which cytokeratin 17 induces epithelial-mesenchymal transition promotes progression. In this study, 78 tissue specimens were collected, expression level (CK17) paracancerous tissues was detected immunohistochemistry, relationship between...
Abstract This study was conducted to investigate the antioxidant, antibacterial, and antiproliferative activities of flesh free (FF), bound (FB), peel (PF), (PB) phenolics from Fuji apple. The PB, which had highest total phenolic contents (126.15 ± 2.41 mg/100 g wet weight) lowest carbohydrate (34.68 2.78 weight), showed strongest 2,2’‐azinobis‐(3‐ethylbenthiazoline‐6‐sulphonate) (ABTS) radical scavenging activity (EC 50 = 0.36 0.02 mg/mL), 1,1‐diphenyl‐2‐picryhydrazyl (DPPH) 0.26 0.01...
Autoimmune thyroiditis (AIT), also known as Hashimoto's (HT), is an autoimmune disease that characterised by elevated thyroid-specific antibody titres. The incidence of AIT increasing year over year, making it urgent to establish a suitable animal model for this condition, in order better explore its pathogenesis and potential pharmaceutical mechanisms treatment. Owing lack basic research on disease, problems such disparate modelling methods with unclear varying success rates make difficult...
Abstract Progressive cardiac remodeling, including the myopathic process in adjacent zone following myocardial infarction (MI), contributes greatly to development of failure. Cardiomyoplasty using bone marrow-derived mesenchymal stem cells (MSCs) has been demonstrated protect cardiomyocytes and/or repair damaged myocardium, leading improved performance, but therapeutic effects on remodeling are still under investigation. Here, we tested hypothesis that MSCs could improve pathological...
Abstract Radiation‐induced lung injury ( RILI ) is a potentially fatal and dose‐limiting complication of thoracic radiotherapy. This study was to investigate the protective effects grape seed pro‐anthocyanidins GSP s), an efficient antioxidant anti‐carcinogenic agent, on . In our study, it demonstrated that acute late ameliorated after s treatment possibly through suppressing TGF ‐β1/Smad3/Snail signalling pathway modulating levels cytokines (interferon‐γ, IL ‐4 ‐13) derived from Th1/Th2...
Whether the alternated microbiota in gut contribute to risk of allograft rejection (AR) and pulmonary infection (PI) setting lung transplant recipients (LTRs) remains unexplored. A prospective multicenter cohort LTRs was identified four centers. Paired fecal serum specimens were collected divided into AR, PI, event-free (EF) groups according diagnosis at sampling. Fecal samples determined by metagenomic sequencing. And metabolites cytokines detected paired analyze potential effect altered...
Abstract BACKGROUND Carboxymethylpachymaran (CMP) is created by carboxymethylating pachyman (PM), which increases its water solubility and enhances a number of biological activities. Traditional polysaccharides modified carboxymethylation employ strong chemical techniques. Carboxymethylcellulose (CMC) has been used previously for liquid fermentation to carboxymethyl modify bacterial polysaccharides. This theory can be applied fungal because Poria cocos the ability naturally utilize...
Introduction. Trichophyton rubrum is a major causative agent of superficial dermatomycoses such as onychomycosis and tinea pedis. Huangqin decoction (HQD), classical traditional Chinese medicine formula, was found to inhibit the growth common clinical dermatophytes T. in our previous drug susceptibility experiments. Hypothesis/Gap Statement. The antifungal activity potential mechanism HQD against have not yet been investigated. Aim. aim this study investigate explore action . Methodology....
Abstract Ionising radiation exposure can lead to acute haematopoietic syndrome. Despite significant advancements in the field of radioprotection, no drugs with high efficacy and low toxicity have yet been approved by Food Drug Administration. FG‐4592, as a proline hydroxylase inhibitor, may play an important role radioprotection system. Mice were peritoneal injected FG‐4592 or normal saline. After irradiation, survival time, body weight, peripheral blood cell bone marrow (BMC) count,...