A5058150652- Systemic Lupus Erythematosus Research
- Immunodeficiency and Autoimmune Disorders
- Autoimmune and Inflammatory Disorders Research
- Child and Adolescent Health
- Diabetes and associated disorders
- Adolescent and Pediatric Healthcare
- Asthma and respiratory diseases
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Celiac Disease Research and Management
- Allergic Rhinitis and Sensitization
- Galectins and Cancer Biology
- T-cell and B-cell Immunology
- Contact Dermatitis and Allergies
- Acute Lymphoblastic Leukemia research
Hospital for Sick Children
2019-2025
Tecnológico de Monterrey
2024-2025
Hospital Infantil de México Federico Gómez
2017
İstanbul Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi
2017
Hacettepe University
2017
Hospital Universitario de Gran Canaria Doctor Negrín
2012
Objective Estimate the prevalence of allergic, neurodevelopmental, and autoimmune diagnoses in children born to anti‐Ro antibody positive mothers. Methods A cohort study mothers followed Neonatal Lupus Erythematosus clinic (NLE) at SickKids Hospital. Participants ≥ 1 year age were invited complete a health status questionnaire. Prevalence disease compared between from NLE non‐NLE population‐based CHILD Cohort Study. Descriptive statistics used for demographics, manifestations outcomes....
Neonatal lupus erythematosus (NLE) is a passively acquired autoimmune disease in infants born to anti-Ro and/or anti-La autoantibody-positive mothers. Genetics may affect NLE risk. We analyzed the genetics of and antibody-positive mothers, with NLE-specific manifestations.
Objective To evaluate the association between ethnicity and neonatal lupus erythematosus (NLE), as well specific NLE manifestations in a large multiethnic population. Methods We conducted cohort study of children (≤ 1 yr age) seen clinic at The Hospital for Sick Children (SickKids), January 2011 April 2019. was divided into European, non-European, mixed European–non-European groups according to parent-reported child’s (Canada Census categories). Outcomes were (cardiac, cutaneous, cytopenias,...
Introduction: Behçet's disease is a complex multisystemic with variable vasculitis.The most prevalent in the Eastern Mediterranean, Middle East, and East Asia, along ancient Silk Road.The typical triad oral ulcers, genital ulcers ocular inflammation.But other clinical manifestations due to vasculitis thrombosis, involvement of gastrointestinal system, nervous system musculoskeletal can be seen variably.Although it young adulthood, one-forth cases are diagnosed during childhood.There long...
Objective We examined the association between schizophrenia genetic susceptibility loci and neuropsychiatric systemic lupus erythematosus (NPSLE) features in childhood-onset SLE (cSLE) participants. Methods Study participants from Lupus Clinic at Hospital for Sick Children, Toronto, met ≥ 4 of American College Rheumatology and/or International Collaborating Clinics classification criteria were genotyped using Illumina Multi-Ethnic Global Array or Screening Array. Ungenotyped...
Introduction: Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenopathy (PFAPA) syndrome is a non Mendelian autoinflammatory disorder until now considered to be specifically limited paediatric age.However there recently mounting evidence that children older than 5 years adults may present with the typical picture of PFAPA syndrome.Objectives: We report case 17,5 old girl presenting recurrent episodes fever starting at age 16.Methods: A was referred our department due lasting...
<h3>Background</h3> Macrophage activation syndrome (MAS) is a serious, potentially fatal complication of childhood systemic inflammatory disorders, and it most frequent in Systemic Juvenile Idiopthic Arthritis, for instance, increasingly reported other pediatric rheumatic diseases as lupus erythematosus Kawasaki disease. <h3>Objectives</h3> To describe clinical case report 16 year old girl with Juvenil Lupus Erythematosus Activation Syndrome refractory. <h3>Methods</h3> A 16-year-old woman...
<h3>Background</h3> Neonatal Lupus (NL) is an acquired autoimmune disorder of newborns secondary to the transplacental passage maternal anti-Ro and/or anti-La. Approximately 2% children exposed these antibodies develop NL. Prior studies have suggested that babies non-European ancestry a higher proportion cardiac NL when compared European ancestry. This finding has not been consistently replicated. <h3>Objectives</h3> To examine association between ethnicity and clinical manifestations in our...