A5050409903- Kawasaki Disease and Coronary Complications
- Autoimmune and Inflammatory Disorders Research
- Coronary Artery Anomalies
- Systemic Lupus Erythematosus Research
- Cardiovascular Issues in Pregnancy
- Adolescent and Pediatric Healthcare
- Vasculitis and related conditions
- Mechanical Circulatory Support Devices
- Immunodeficiency and Autoimmune Disorders
- Inflammatory Myopathies and Dermatomyositis
- Systemic Sclerosis and Related Diseases
- Streptococcal Infections and Treatments
- Cardiac Structural Anomalies and Repair
- Inflammasome and immune disorders
- Lymphadenopathy Diagnosis and Analysis
- Neurogenetic and Muscular Disorders Research
- Salivary Gland Disorders and Functions
- Atherosclerosis and Cardiovascular Diseases
- Childhood Cancer Survivors' Quality of Life
- Platelet Disorders and Treatments
- T-cell and B-cell Immunology
- Oral Health Pathology and Treatment
- COVID-19 Clinical Research Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Blood disorders and treatments
Hospital Infantil de México Federico Gómez
2015-2024
Centro Médico ABC
2023
University of Campania "Luigi Vanvitelli"
2022
Hacettepe University
2017
Ümraniye Eğitim ve Araştırma Hastanesi
2017
Istanbul University
2017
Mayo Clinic
2014
Abstract Objectives To characterize the phenotypic presentation at diagnosis of childhood-onset primary SS. Methods The Big Data Sjögren Project Consortium is an international, multicentre registry using worldwide data-sharing cooperative merging pre-existing clinical SS databases from five continents. For this study, we selected those patients in whom disease was diagnosed below age 19 years according to fulfilment 2002/2016 classification criteria. Results Among 12 083 included Registry,...
To evaluate factors associated with mortality and infections in patients systemic lupus erythematosus (SLE) diffuse alveolar hemorrhage (DAH).A retrospective chart review was carried out for medical admissions of a diagnosis SLE DAH 9 hospitals. Clinical laboratory data were recorded each patient at diagnosis.We included 57 episodes 50 (7 recurrences), 49 women (86%), 14 juvenile (24.6%); 24 had died (42.1%). In the we detected infection 22 (38.6%): 8 invasive fungal infections, 16 bacterial...
Musculoskeletal Ultrasonography (MSUS) is an important tool for the clinical assessment in Juvenile Idiopathic Arthritis (JIA). The objective of this study was to evaluate reliability MSUS detect elementary lesions: synovitis, tenosynovitis, cartilage damage and bone erosions wrist metacarpal (MCP) joints patients with JIA.Thirty children various subgroups JIA according ILAR criteria, were included cross-sectional study. Clinical data including painful, swollen limited recorded. Five...
Background: Multisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease 2019 varies widely its presentation and severity, low mortality high-income countries. In this study 16 Latin American countries, we sought to characterize patients MIS-C the pediatric intensive care unit (PICU) compared those hospitalized on general wards analyze factors outcomes, treatment received. Study Design: An observational ambispective cohort was conducted including 1 month 18 years...
BACKGROUND Multisystem inflammatory syndrome (MIS-C) represents a diagnostic challenge because of its overlap with Kawasaki disease, disease shock syndrome, and toxic syndrome. Macrophage activation (MAS) is frequently fatal complication various pediatric disorders has been reported in MIS-C. Early diagnosis prompt initiation by immune modulating therapies are essential for effectively managing MAS. METHODS We conducted retrospective study to determine the frequency, natural history,...
Objective: To characterize the clinical presentation and outcomes of Kawasaki disease (KD) in infants 10 days (50% vs 7.4%, P = 0.043). Conclusion: Our data show that despite treatment first illness, < 6 months age Latin America have a higher risk developing coronary artery aneurysm. Delay diagnosis leads to larger aneurysms disproportionately these infants. Thus, suspicion for KD should be high this vulnerable population.
ObjectivesTo describe the clinical presentation, management, and outcomes of Kawasaki disease (KD) in Latin America to evaluate early prognostic indicators coronary artery aneurysm (CAA).Study designAn observational KD registry-based study was conducted 64 participating pediatric centers across 19 American countries retrospectively between January 1, 2009, December 31, 2013, prospectively from June 2014, May 2017. Demographic initial laboratory data were collected. Logistic regression...
Rheumatic diseases in children are associated with significant morbidity andpoor health-related quality of life (HRQOL). There is no health-relatedquality (HRQOL) scale available specifically for lesscommon rheumatic diseases. These share several features withsystemic lupus erythematosus (SLE) such as their chronic episodic nature,multi-systemic involvement, and the need immunosuppressive medications.HRQOL developed pediatric SLE will likely be applicable tochildren systemic inflammatory We...
La enfermedad de Kawasaki (EK) es una las vasculitis sistémicas más comunes en niños menores 5 años edad. epidemiología la no está bien establecida México. El objetivo este trabajo fue describir epidemiología, características clínicas y tratamiento los pacientes con EK atendidos el Hospital Infantil México Federico Gómez (HIMFG). Se realizó un estudio retrospectivo, descriptivo analítico diagnosticados HIMFG periodo comprendido entre enero 2004 diciembre 2014. analizaron 204 casos, mayoría...
Abstract Background Pediatric rheumatic disease (PRD) patients and their caregivers face a number of challenges, including the consequences PRD in impact on multiple dimensions caregivers’ daily lives. The objective this study is to measure economic, psychological social that has Mexican children. Methods This multicenter, cross-sectional primary children adolescents with (JIA, JDM JSLE) during April November, 2019. A trained interviewer conducted CAREGIVERS questionnaire, specific, 28-item...
Introduction: Behçet's disease is a complex multisystemic with variable vasculitis.The most prevalent in the Eastern Mediterranean, Middle East, and East Asia, along ancient Silk Road.The typical triad oral ulcers, genital ulcers ocular inflammation.But other clinical manifestations due to vasculitis thrombosis, involvement of gastrointestinal system, nervous system musculoskeletal can be seen variably.Although it young adulthood, one-forth cases are diagnosed during childhood.There long...
To describe characteristics of patients with the pediatric inflammatory multisystem syndrome, temporally associated SARS-CoV-2 (PIMS-TS)/multisystem syndrome in children (MIS-C) and to identify factors admission intensive care unit (PICU) Mexican without coronavirus disease 2019 (COVID-19) vaccination.This was a cross-sectional study performed at Hospital Infantil de Mexico Federico Gomez, referral children's hospital Mexico. The included all cases that met criteria for PIMS-TS/MIS-C,...
To develop and externally validate a prediction model for new-onset chronic uveitis in children with juvenile idiopathic arthritis (JIA) clinical application.
To assess the relationship between infection risk and abatacept (ABA) exposure levels in patients with polyarticular-course juvenile idiopathic arthritis (pJIA) following treatment subcutaneous (SC) intravenous (IV) ABA.Data from 2 published studies (ClinicalTrials.gov: NCT01844518, NCT00095173) of ABA pediatric were analyzed. One study treated aged 2-17 years SC other 6-17 IV ABA. Association serum measures was evaluated using Kaplan-Meier plots probability first vs time on by quartiles...
Kawasaki disease (KD) is one of the most common systemic vasculitis in children under five years age. The epidemiology not well established Mexico. objective this study was to describe epidemiology, clinical features and treatment patients with KD at Hospital Infantil de Mexico Federico Gomez (HIMFG). We conducted a retrospective, descriptive analytical diagnosed from January 2004 December 2014 HIMFG. analyzed 204 cases which 55% were male, median age 32.5 months (6-120) rate hospitalization...
<h3>Background</h3> Multisystem Inflammatory Syndrome in Children (MIS-C) is one of the most feared complications following SARS-CoV2 infection children and adolescents. Few multinational multicenter studies from Latin America have been published. <h3>Objectives</h3> To describe clinical presentation, management, outcomes MIS-C America. <h3>Methods</h3> Observational, prospective retrospective, study to gather information 84 participating centers across 16 American countries, between August...
The objective was to characterize the use of adjunctive therapy in Kawasaki disease (KD) Latin America between January 1st, 2009 and May 31st, 2017. Of these patients, 1152 received only a single dose IVIG 266 additional treatment. Age at onset similar both groups (median 2 vs 2.2 years, respectively); majority were male (58% 63.9%) hospitalized with first 10 days fever (85.1% 84.2%). most common administered steroids for IVIG-resistance, followed by doses IVIG. biologics such as infliximab...
Abstract Background Recently, hoarseness affecting the supraglottic structure has been reported in Kawasaki disease (KD). The objective of this study was to characterize frequency acute KD patients Latin America. Methods We used prospective data from multinational Red de Enfermedad en America Latina (REKAMLATINA) network. A total 865 20 countries were enrolled during 3 year period. Data on available 858 (99.2%) patients. clinical and laboratory characteristics between hoarse non‐hoarse...
OBJECTIVES. To characterize the phenotypic presentation at diagnosis of childhood-onset primary Sjogren syndrome (SjS). METHODS. The Big Data Project Consortium is an international, multicentre registry using worldwide data-sharing cooperative merging pre-existing clinical SjS databases from five continents. For this study, we selected those patients in whom disease was diagnosed below age 19 according to fulfilment 2002/2016 classification criteria. RESULTS. Among 12,083 included Registry,...
<h3>Objective</h3> Analyze prognostic factors for chronic kidney disease progression in Mexican patients with class V lupus nephritis (LN), comparing them mixed classes. <h3>Methods</h3> Retrospective cohort, 74 12–80 years old from 4 different hospitals: 33% LN V, 23% III+V and 43.2% IV+V. <h3>Results</h3> Sixty-two females (83.7%), mean age 33 (12–63), 59.5% had hypertension, 6.8% type 2 diabetes 8.1% antiphospholipid antibody syndrome. Twelve-month follow-up eGFR <60...