- Meningioma and schwannoma management
- Head and Neck Surgical Oncology
- Glioma Diagnosis and Treatment
- Spinal Fractures and Fixation Techniques
- Cerebrospinal fluid and hydrocephalus
- Spine and Intervertebral Disc Pathology
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurosurgical Procedures and Complications
- Neurofibromatosis and Schwannoma Cases
- Vascular Malformations Diagnosis and Treatment
- Pituitary Gland Disorders and Treatments
- Brain Metastases and Treatment
- Management of metastatic bone disease
- Intracranial Aneurysms: Treatment and Complications
- Neurological disorders and treatments
- Ophthalmology and Eye Disorders
- Facial Trauma and Fracture Management
- Vestibular and auditory disorders
- Craniofacial Disorders and Treatments
- Cerebral Venous Sinus Thrombosis
- Cervical and Thoracic Myelopathy
- Anatomy and Medical Technology
- Infectious Diseases and Tuberculosis
- Bone Tumor Diagnosis and Treatments
- Parkinson's Disease Mechanisms and Treatments
Marche Polytechnic University
2016-2025
Ospedali Riuniti Umberto I
2003-2024
Istituto Nazionale di Riposo e Cura per Anziani
2024
Istituti di Ricovero e Cura a Carattere Scientifico
2024
Russian Academy of Sciences
2023
Institute of Bioorganic Chemistry
2023
Institute of Neurological Sciences
2023
Tampere University Hospital
2023
Hospital de Santa Maria
2023
Kempenhaeghe
2023
The efficacy of deep brain stimulation the anterior nucleus thalamus (ANT DBS) in patients with drug-resistant epilepsy (DRE) was demonstrated double-blind Stimulation Anterior Nucleus Thalamus for Epilepsy randomized controlled trial. Medtronic Registry (MORE) aims to understand safety and longer-term effectiveness ANT DBS therapy routine clinical practice.
Article abstract-Objective: To identify disease patterns in AIDS-related focal brain lesions (FBL) and to design a decision-making strategy for differential diagnosis. Design: Prospective study. Probabilities of CNS disorders were calculated using Bayes9 theorem according clinical variables (mass effect at CT or MRI, Toxoplasma serology, anti-Toxoplasma prophylaxis) the results polymerase chain reaction (PCR) assays. Patients: 136 consecutive HIV-infected patients with definitive diagnosis...
OBJECTIVE: To assess the role of surgery on survival patients with grade II gliomas cerebral hemispheres. METHODS: One hundred and thirty one low hemispheric surgically treated (biopsied excluded) between 1978 1989 were retrospectively reviewed. Thalamic, basal ganglia, callosal, or ventricular location not considered. All tumours World Health Organisation (WHO) gliomas: 42 fibrillary 11 gemistocytic astrocytomas, 49 oligodendrogliomas, 29 oligoastrocytomas. Patients9 ages ranged from 14 to...
Background: Refractory Meniere's disease (MD) is a disabling disease; moreover, selective vestibular neurectomy (VN), in these selected cases of drug-resistant pathology, can be considered an alternative surgical option order to preserve hearing and facial nerve function.
BACKGROUND: Extended reality (XR) systems play an increasingly role in preoperative planning different surgical fields including neurosurgery. Considering educational purposes, not all residents have the same opportunities to learn and deal with XR. Thus, authors sought evaluate perspectives of Italian sample neurosurgical trainees on XR, size impact these developing technologies learning curve a small group coming from Institutions.METHODS: A 23-question cross-sectional survey was...
The list of complications reported after decompressive craniectomy (DC) and cranioplasty is progressively increasing. Nonetheless, the exact incidence these events still ill-defined. Problems affecting skin flaps DC have never been accurately analyzed in papers their impact on patients' prognosis largely underestimated.In a 10-year time, we treated by 450 patients, 344 whom underwent cranioplasty, either with autologous bone or artificial implants (hydroxyapatite, polyetheretherketone,...
In order to identify the incidence, risk factors and prognostic indicators of postneurosurgical bacterial meningitis, a 9-y retrospective cohort study was performed. The comprised 3580 individuals who underwent neurosurgical operations at Department Neurosurgery Catholic University, Rome, 1,700-bed university hospital. We observed 52 episodes with infection rates 1.4/100 patients, 0.8/100 for craniotomies 2.6/100 internal cerebrospinal fluid (CSF) shunt or ventriculostomy external drainage....
We used light and electron microscopic immunocytochemical techniques to analyze the distribution, cellular synaptic localization of EAAT2, main glutamate transporter, in normal human neocortex. EAAT2a immunoreactivity was all layers consisted small neuropilar puncta rare cells. In white matter EAAT2a+ cells were numerous. Electron studies showed that gray ∼77% immunoreactive elements astrocytic processes, ∼14% axon terminals, ∼2.8% dendrites, whereas ∼5% unidentifiable. matter, ∼81% ∼17%...
Abstract: Giant cell tumors (GCTs) are primary bone neoplasms that rarely involve the skull base. These lesions usually locally aggressive and require complete removal, including surrounding apparently healthy bone, to provide best chance of cure. GCTs, as well other located in clivus, can nowadays be treated by a minimally invasive fully endoscopic extended endonasal approach. This approach ensures more direct route craniovertebral junction than possible approaches (transfacial, lateral,...
Colloid cysts are histologically benign lesions whose primary goal of treatment should be complete resection to avoid recurrence and sudden death. Open surgery is traditionally considered the standard approach, but, recently, endoscopic technique has been recognized as a viable safe alternative microsurgery. The approach colloid third ventricle usually performed through foramen Monro. However, this route does not provide adequate visualization cyst attachment on tela choroidea. combined...
The most important target of minimally invasive surgery is to obtain the best therapeutic effect with least iatrogenic injury. In this background, a pivotal role in contemporary neurosurgery played by supraorbital key-hole approach proposed Perneczky for anterior cranial base surgery. article, it presented as possible valid alternative traditional craniotomies fossa meningiomas removal. From January 2008 2012 at our department 56 patients underwent Thirty-three were submitted approaches...