A5046306013- Epilepsy research and treatment
- EEG and Brain-Computer Interfaces
- Neurological disorders and treatments
- Heart Rate Variability and Autonomic Control
- Pharmacological Effects and Toxicity Studies
- Particle Detector Development and Performance
- Neuroscience and Neuropharmacology Research
- Neuroscience and Neural Engineering
- Cardiac Imaging and Diagnostics
- Superconducting Materials and Applications
- Functional Brain Connectivity Studies
- Pregnancy and Medication Impact
- Advanced MRI Techniques and Applications
- Particle physics theoretical and experimental studies
- Bipolar Disorder and Treatment
- Genetics and Neurodevelopmental Disorders
- Muon and positron interactions and applications
- Cardiovascular Function and Risk Factors
- Histiocytic Disorders and Treatments
- Clinical Reasoning and Diagnostic Skills
- Electroconvulsive Therapy Studies
- Neonatal and fetal brain pathology
- Cardiovascular Disease and Adiposity
- Advanced Neuroimaging Techniques and Applications
- Neurology and Historical Studies
Hospital de São João
2014-2025
Academic Rights Press (United Kingdom)
2024
Universidade Federal do Rio Grande do Norte
2024
Centro Hospitalar do Porto
2022-2024
Administração Regional de Saúde de Lisboa e Vale do Tejo
2024
Universidade do Estado do Rio Grande do Norte
2024
Portuguese League Against Epilepsy
2024
Universidade do Porto
2023
Tampere University Hospital
2023
Hospital de Santa Maria
2023
The efficacy of deep brain stimulation the anterior nucleus thalamus (ANT DBS) in patients with drug-resistant epilepsy (DRE) was demonstrated double-blind Stimulation Anterior Nucleus Thalamus for Epilepsy randomized controlled trial. Medtronic Registry (MORE) aims to understand safety and longer-term effectiveness ANT DBS therapy routine clinical practice.
Objetivo: Apresentar um desfecho clínico favorável ao uso da Eletroconvulsoterapia (ECT) em uma paciente idosa com Catatonia Depressiva Refratária, destacando a relevância dessa abordagem terapêutica e corroborando sua eficácia. Relato de Caso: Paciente do sexo feminino, 84 anos, diagnóstico Transtorno Depressivo Maior, evoluindo para Associada à Depressão. Após anos manejo benzodiazepínicos antipsicóticos sem resposta clínica satisfatória, conforme avaliação pela escala BFCRS, implementação...
Abstract Objective Epilepsy surgery is a standard treatment for drug‐resistant epilepsy, resulting in seizure freedom significant number of cases. Although frequently performed low‐grade brain tumors, it rarely considered high‐grade despite the impact chronic epilepsy on quality life and cognition. Methods This retrospective multicenter study across 43 European centers evaluated outcomes children with tumors (World Health Organization grades III IV). Two cohorts patients younger than 25...
Vocalizations may occur in focal epileptic seizures, which typically arise from frontal and temporal regions. They are commonly associated with other motor phenomena such as automatisms, tonic posturing, or head version. We report on a patient whose seizures were documented by video-EEG monitoring, but whom the observable ictal semiology consisted solely of brief, monotonous vocalization. Ictal EEGs showed left seizure patterns. Isolated vocalizations can constitute an event be only clinical...
Background and purpose We evaluated two methods to identify mesial temporal sclerosis (MTS): visual inspection by experienced epilepsy neuroradiologists based on structural magnetic resonance imaging sequences automated hippocampal volumetry provided a processing pipeline the FMRIB Software Library. Methods This retrospective study included patients from monitoring unit database of our institution. All underwent brain in 1.5T 3T scanners with protocols that thin coronal T2, T1...
ABSTRACT The clinical symptoms associated with chromosome 15q duplication syndrome manifest through a heterogeneous group of characterised by hypotonia, delay in motor skills and language development, cognitive learning disabilities, autism spectrum disorder refractory epilepsy. late development Lennox‐Gastaut patients 15q11q13 is possibility that physicians should be aware of. We report the case 27‐year‐old man neurodevelopmental due to duplication, intellectual disability, psychiatric...
Deep brain stimulation of the Anterior Nucleus Thalamus (ANT-DBS) is an effective therapy in epilepsy. Poorer surgical outcomes are related to deviations lead from ANT-target. The target identification relies on visualization anatomical structures by medical imaging, which presents some disadvantages. This study aims research whether ANT-LFPs recorded with PerceptTM PC neurostimulator can be asset DBS-target. For this purpose, 17 features were extracted LFPs a single patient, who stayed at...
ABSTRACT Aim : This study aimed to characterize, clinically and neurophysiologically, a series of patients with gelastic seizures (GS), including both adults children. Methods We retrospectively collected GS from epilepsy clinics five tertiary hospital centres within single country. Patients were selected through relatives’/caregivers’ descriptions, home video and/or video‐EEG monitoring. identified ictal semiology. Results Thirty‐five enrolled; 62.9% had initial in infancy, 14.3%...
Abstract Postictal paresis (“Todd's paralysis”) is commonly observed as a unilateral, transient motor weakness, lasting minutes to hours, after focal or bilateral tonic–clonic seizures, contralateral the epileptogenic zone. Bilateral postictal exceedingly rare and could be misinterpreted, especially if preceding convulsive phase was not witnessed. An 18‐year‐old right‐handed male patient with refractory epilepsy seizure onset at age 3 years, admitted for presurgical video‐EEG monitoring. His...
Adaptive Deep Brain Stimulation has recently emerged to tackle conventional DBS limitations by measuring disease fluctuations and adapt stimulation parameter accordingly. In early 2020, Medtronic launched in the European Union first certified neurostimulator capable of simultaneously stimulate read signals from deep brain structures, PerceptTMPC. epilepsy, most common target structure is Anterior Nucleus Thalamus Local Field Potentials analysis requires prior synchronization data recorded...
The Anterior Nucleus of Thalamus (ANT) Deep Brain Stimulation (DBS) has long been touted as the most effective DBS-target for interrupting seizures in focal refractory epilepsy patients. ANT is primarily involved cognitive tasks but extensive reciprocal connections with motor-related regions, suggesting that it also motor-cognitive tasks. In this work, we aimed to assess involvement during voluntary upper limbs movements. For purpose, analyzed Local Field Potentials (LFPs) signals recorded a...
When performing pre-surgical evaluation of patients with refractory epilepsy, the analysis seizure semiology is one key elements used to generate a hypothesis about location epileptogenic zone. Ictal kissing very rarely observed ictal automatism described in temporal lobe epilepsy. We present 62-year-old man who was referred our epilepsy centre for comprehensive evaluation. During prolonged video-EEG monitoring, six focal-onset hyperkinetic seizures were registered. In five seizures, patient...
Summary: Periodic limb movements (PLMs) may occur as a primary condition or be associated with other pathologies, such sleep disorders. However, PLMs have not been described in comatose patients. We report the case of 66-year-old man, no history disorders, who presented during coma caused by an extensive right hemispheric abscess inducing midline shift. These were further characterized video and electromyographic recordings, which displayed bilateral periodic bursts tibialis anterior...