- Advanced Data Processing Techniques
- Autoimmune and Inflammatory Disorders Research
- Adolescent and Pediatric Healthcare
- Kawasaki Disease and Coronary Complications
- Smart Grid Energy Management
- Fault Detection and Control Systems
- Nonlinear Dynamics and Pattern Formation
- Venous Thromboembolism Diagnosis and Management
- Quantum Computing Algorithms and Architecture
- Advanced Thermodynamics and Statistical Mechanics
- Engineering Diagnostics and Reliability
- Mathematical Biology Tumor Growth
- Smart Grid and Power Systems
- Coronary Artery Anomalies
- Vascular Procedures and Complications
- Computational Physics and Python Applications
- Electric and Hybrid Vehicle Technologies
- Peripheral Artery Disease Management
- Gear and Bearing Dynamics Analysis
- Protein Structure and Dynamics
- Cardiovascular Issues in Pregnancy
- Orthopedic Infections and Treatments
- Statistical Mechanics and Entropy
- Muscle and Compartmental Disorders
- Power Systems and Renewable Energy
Medical University of Sofia
2013-2024
Technical University of Varna
2021-2024
University Hospital St. Ivan Rilski
2024
Institute of Electrochemistry and Energy Systems
2022
Acibadem City Clinic
2019
Hospital Universitario La Paz
2008-2015
Medical University Pleven
2012
University of Central Oklahoma
2006
Instituto de Cardiología y Cirugía Cardiovascular
2005
Alexandrovska Hospital
2001
In this secondary analysis of the VOYAGER trial, rivaroxaban 2.5 mg twice/day plus aspirin 100 mg/day was assessed in older adults. Advanced age is associated with elevated bleeding risk and unfavourable net benefit for dual antiplatelet therapy chronic coronary artery disease. The risk-benefit low-dose patients ≥75 years peripheral disease (PAD) after lower extremity revascularization (LER) has not been described.The primary endpoint a composite acute limb ischaemia, major amputation,...
Aortouniiliac stent grafts allow the endovascular treatment of complex anatomy aortoiliac aneurysms. The main drawback is need for femoro-femoral crossover bypass, with its complications and patency limitations. However, some authors have shown good results bypass in aneurysmal disease. In this article, initial long-term our experience revascularization after aortouniiliac repair aneurysms reported. Prospective collection, intention-to-treat, retrospective analysis maintained database....
Autoimmunity is becoming an increasingly recognized complication in patients with primary immunodeficiencies (PIDs), including a variety of combined immune deficiencies such as Recombination Activating Gene (RAG) defects. The approach to treating autoimmunity PID complex, requiring balance between immunosuppression and susceptibility infection. Inflammatory arthritis feature dysregulation many PIDs, the optimal treatment may differ from first line therapies that usually consist...
Carotid artery injuries with pseudoaneurysm are uncommon but associated central neurologic dysfunction. We present a case of posttraumatic the right common carotid treated by implantation covered stent. A 44-year-old woman multiple after fall from height presents small dissection flap (RCCA) on initial computed tomography angiography (CTA). Fifteen days later 10 mm is observed control CTA. decided endovascular treatment. Through femoral access long introducer sheath placed in innominate...
We report a clinical case of 4-year-and-10-month-old boy whose first symptoms (fever and tachypnoea) were noticed at the age 6 months. In upcoming months, skin acral violaceous plaques developed. Failure to thrive growth impairment detected. journey find correct diagnosis, lot diseases suspected. The final diagnosis was suggested after more than 2 years since had appeared. A multi-detector computed tomography chest with low radiation dose protocol showed signs interstitial lung disease...
The aim of this study was to investigate whether the C677T and A1298C polymorphisms methylenetetrahydrofolate reductase (MTHFR) gene might be related prediction toxicity efficacy methotrexate (MTX) in juvenile idiopathic arthritis (JIA) clinical practice. Sixty-three patients (50 girls 13 boys) fulfilling International League Associations for Rheumatology (ILAR) criteria JIA were included study. Patients divided into two groups – those undergoing treatment with MTX monotherapy putative...
Critically reviewed in the present paper is principle of operation a model family eight-speed automatic transmissions manufactured by company Aisin Warner. A comprehensive kinematic analysis gearbox design was conducted, along with close examination potential defects that may arise during operation. The underlying causes these were identified and discussed detail. Explored, further paper, functionality solenoids valve body outlined, additionally, are methods for determining their...
Cilia-like sensitivity observer, at an adaptive treatment of a tumor recurrence in active soft matter, is built. Therefore, the activity matter shown as colloidal chains with cilia-like and flagella-like motility; recurrence, considered run-away/quantum aging matter; energy defined electromagnetic field energy, stabilizing or destabilizing life, force dipole. Information recovery fulfilled via two quantum extremal islands. obtained for mean maximum-tolerated dose growth matter. There are...
A Mullins simulation was conducted to analyze the effects of loading and unloading a flexible-type SEGE coupling with nominal torque Tnom=80 Nm maximum Tmax=120 Nm. The coupling's properties were determined by examining its moment characteristics at T=120, 100, 80, 60, 40, 20 correlation between effect results obtained from load via SolidWorks 2022 software actual experimental data examined.
Kawasaki disease (KD) is an acute systemic vasculitis that affects medium-sized vessels, particularly the coronary arteries. KD predominantly children under 5 years of age. Main symptoms include fever, bilateral conjunctivitis, polymorphous exanthema, oropharyngeal mucous membranes changes, palmar and/or plantar erythema and edema, cervical lymphadenopathy. can present with a few clinical features, which might lead to delayed diagnosis, in infants. When therapy delayed, diagnosis missed or...
Introduction : Tuberculous osteoarthritis, caused by Mycobacterium tuberculosis, is a very rare extrapulmonary manifestation of especially in children. Aim This article presents clinical case 21-month-old male patient with tuberculous osteoarthritis affecting the ankle joint. The rarity this pathology underscores critical importance swift diagnosis and multidisciplinary approach involving specialists from diverse medical fields. Results Early initiation specific antituberculous treatment,...
The paper suggests Daily Artificial Dispatcher (DAD), as an ambient intelligence that solves the problem for automatic predictive analysis of electric power system (EPS) security and efficiency, using EPS weather summarized data. DAD is constructed heading EPS, implementing common sense thinking a day ahead EPS. verified, it shown intentional agent, robot, intelligent system. validated, adequate efficiency computation.
Kawasaki disease (KD) is one of the most common vasculitis disorders childhood, affecting predominantly medium-sized arteries, particularly coronary arteries. For treatment, high-dose intravenous immunoglobulin (IVIG) indicated. IVIG infusions are usually safe and well tolerated even though serious complications can be observed. We present a brief overview KD report two-year-old girl with two (Gammagard®) because persistent fever after completion first IVIG. Haemolytic anaemia developed...
A prognostic watch of the electric power system (EPS)is framed up, which detects threat to EPS for a day ahead according characteristic times and droop ahead. Therefore, analysis development is carried out. Also grid, electricity marker state, grid state level are found The accuracy built up evaluated.
Kawasaki disease (KD) is a vasculitis syndrome causing coronaritis in young children. As result of the vascular damage, coronary lesions (CL), ectasia and aneurysms form 20%–25% untreated The assessment KD difficult challenging because lack specific diagnostic or laboratory criteria. This retrospective study 107 patients for period 21 years (1993–2014). In cohort, 30.8% had CL (19.6% 11.2% significant dilatations). number was high compared to that reported international studies, although 45%...
Dragon-King a is introduced in this paper as the manifestation of disaster incident for Smart Grid’s blackout day-ahead. The quintessential being generated by an artificial black hole, it then spreads quickly into transmission lines. Consequently, bursts space-time transition regions. This reveals all essential characteristics Dragon-King, has non-isotropic stochastic kinematics. Regardless its huge unwanted phenomena, controllable. We also describe mechanism updated complexity, spinning...
The paper deals with a wind wave, which is day-ahead wave healing of power grid lots farms and transmission fault. This restores synchronization shape grid. restoration achieved by Casimir force, adjusted an energy spike. via spike, the change free
In this paper, a day-ahead anticipation of complex network vulnerability for an intentional threat attack or shock is carried out. An ecological observer introduced that reason, which watch in the multiverse, tiled by cells; dynamics characterized space-time cell; spreading derived from its energy; duration found self-assembling lower bound probability assessed to anticipate threat; it indicated right when leads dimension doubling network.
Addressed in the present paper are options to test an internal combustion engine on a designed and constructed hydraulic dynamometer. Hydraulic dynamometers combine high power ratings with low moment of inertia case they good alternative other braking systems. Extensively discussed is option load dynamometer through valve creating backpressure at outlet. Reviewed, additionally, also measure pressure gauge engine-dynamometer system resilience. Derived, accordingly, dependences control....
Kawasaki disease (KD) is a childhood vasculitis syndrome and the coronary arteries are main target of vascular damage. The outcome formation lesions (CL) that develop in 20%–25% untreated children. KD leading cause myocardial infarction infancy. Its consequences among young people acute susceptibility to early atherosclerosis, if were remain unrecognized. We investigated cardiac manifestations during phase disease, values fever, C-reactive protein (CRP) erythrocyte sedimentation rate (ESR)...