Qian Zhang

ORCID: 0000-0002-3859-6503
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About
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Research Areas
  • Traditional Chinese Medicine Analysis
  • Atmospheric chemistry and aerosols
  • Air Quality and Health Impacts
  • Traditional Chinese Medicine Studies
  • Acupuncture Treatment Research Studies
  • Atmospheric Ozone and Climate
  • Neurological Disease Mechanisms and Treatments
  • Natural Compounds in Disease Treatment
  • Healthcare and Venom Research
  • Pharmacological Effects of Natural Compounds
  • Medical Research and Treatments
  • Vehicle emissions and performance
  • Natural product bioactivities and synthesis
  • Plant-based Medicinal Research
  • Nerve injury and regeneration
  • Pluripotent Stem Cells Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Spinal Cord Injury Research
  • Phytochemical and Pharmacological Studies
  • Food Industry and Aquatic Biology
  • Metabolomics and Mass Spectrometry Studies
  • Medicinal Plants and Bioactive Compounds
  • Ginseng Biological Effects and Applications
  • CRISPR and Genetic Engineering
  • Neurogenesis and neuroplasticity mechanisms

Shaanxi Normal University
2021-2025

Beijing University of Chinese Medicine
2012-2025

Hebei Medical University
2025

Xingtai People's Hospital
2025

Shihezi University
2023-2024

Xinjiang Production and Construction Corps
2023-2024

Shaanxi University of Chinese Medicine
2016-2024

Guangxi University
2023-2024

Xi'an Jiaotong University
2014-2023

Guiyang Medical University
2022-2023

Brown carbon (BrC), an aerosol carbonaceous matter component, impacts atmospheric radiation and global climate because of its absorption in the near-ultraviolet–visible region. Simultaneous air sampling was conducted two megacities Xi'an (northern) Hong Kong (southern) China winter 2016–2017. The aim this study is to determine characterize BrC compounds collected filter samples. Characteristic peaks corresponding aromatic C–C stretching bands, organo-nitrates, C═O functional groups were seen...

10.1021/acs.est.9b05332 article EN Environmental Science & Technology 2020-03-09

Celastrol (cel) was one of the earliest isolated and identified chemical constituents Tripterygium wilfordii Hook. f. Based on a cel probe (cel-p) that maintained bioactivity parent compound, targets in cerebral ischemia-reperfusion (I/R) injury were comprehensively analyzed by quantitative proteomics method.We constructed an oxygen-glucose deprivation (OGD) model primary rat cortical neurons middle artery occlusion (MCAO) adult rats to detect direct binding I/R. By combining various...

10.1186/s12974-021-02216-w article EN cc-by Journal of Neuroinflammation 2021-08-09

Abstract Brown Carbon (BrC) absorbs light in wavelength of 300–400 nm, and BrC molecule (BrCM) is a fundamental component responsible for aerosol radiative forcing. In this study, Fourier‐transform ion cyclotron resonance mass spectrometry (FT‐ICR MS) coupled with electrospray ionization (ESI) was used to determine methanol extracted BrCM PM 2.5 collected Xi'an, China. The absorption individual quantified through partial least square regression (PLSR) method. Results showed that 77.5% 91.8%...

10.1029/2021jd034791 article EN Journal of Geophysical Research Atmospheres 2021-08-09

Sea buckthorn berries are important ingredients in Chinese medicine and food processing; however, their high moisture content can reduce shelf life. Effective drying is crucial for extending In the present study, we investigated effects of hot-air (HAD), infrared (IRD), infrared-assisted (IR-HAD), pulsed-vacuum (PVD), vacuum freeze-drying (VFD) on kinetics, microstructure, physicochemical properties (color, non-enzyme browning index, rehydration ratio), total phenol, flavonoid, ascorbic acid...

10.3389/fnut.2023.1106009 article EN cc-by Frontiers in Nutrition 2023-02-08

Solid (biomass and coal) fuels burned for residential heating are major sources of atmospheric volatile organic compounds (VOCs). In this study, VOC samples were collected in-situ from chimneys in 10 typical scenarios rural areas the Guanzhong Plain. A modified SUMA canister approach was then employed, followed by gas chromatography/mass spectrometry analysis. Emission factors (EFs) (as received basis) targeted non-methane VOCs (NMVOCs) varied 90.3 ± 29.3 to 12300 1510 mg kg−1 descending...

10.1016/j.envint.2019.105252 article EN cc-by Environment International 2019-11-02

Abstract Knowledge of the molecular‐level chemistry brown carbon (BrC) is important in reducing uncertainties aerosol radiative forcing. Time‐resolved ambient PM 2.5 samples were collected during a severe pollution episode January 2017 over Xi'an, China for comprehensive nontarget and full scanning BrC molecules their absorption properties using electrospray ionization Fourier transform–ion cyclotron resonance mass spectrometry combined with partial least squares regression analysis, which...

10.1029/2020gl087977 article EN Geophysical Research Letters 2020-04-30

Baicalin is a natural active ingredient isolated from Scutellariae Radix that can cross the blood-brain barrier and exhibits neuroprotective effects on multiple central nervous system diseases. However, mechanism behind remains unclear. In this study, rat models of spinal cord injury were established using modified Allen's impact method then treated with intraperitoneal injection Baicalin. The results revealed greatly increased Basso, Beattie, Bresnahan Locomotor Rating Scale score, reduced...

10.4103/1673-5374.324857 article EN cc-by-nc-sa Neural Regeneration Research 2021-09-19

The use of complementary and alternative medicine (CAM), particularly herbal their derived products, have been increasing. However, sporadic reports serious adverse effects associated with the these products become a source concern. Spontaneous event reporting may be used to monitor safety products.The objectives this study is analyze describe patterns events Chinese Proprietary Medicine, other health supplements (termed CAM products) in Singapore Pharmacovigilance database from 1998 2009...

10.3109/15563650.2012.700402 article EN Clinical Toxicology 2012-06-27

Chlorogenic acid (CGA), which is a natural compound found in various plants, has been reported to exert notable anti‑inflammatory activities. The present study investigated the effects and underlying mechanism of CGA on interleukin (IL)‑1β‑induced osteoarthritis (OA) chondrocytes. An vitro OA‑like chondrocyte model was established using IL‑1β‑stimulated human SW‑1353 Cell viability assessed an MTT assay. Nitric oxide (NO) IL‑6 production were evaluated by Griess reaction ELISA, respectively....

10.3892/mmr.2017.6698 article EN Molecular Medicine Reports 2017-02-01

Myelin injury occurs in brain ageing and several neurological diseases. Failure of spontaneous remyelination is attributable to insufficient differentiation oligodendrocyte precursor cells (OPCs) into mature myelin-forming oligodendrocytes CNS demyelinated lesions. Emerging evidence suggests that peroxisome proliferator-activated receptor γ (PPARγ) the master gatekeeper repair plays an important regulatory role various neurodegenerative Although studies demonstrate positive effects PPARγ...

10.1093/brain/awae378 article EN Brain 2025-01-06
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