A5082766945- Herpesvirus Infections and Treatments
- Animal Virus Infections Studies
- Zoonotic diseases and public health
- Virus-based gene therapy research
- Bird parasitology and diseases
- Turtle Biology and Conservation
- Veterinary Oncology Research
- Virology and Viral Diseases
- Animal Disease Management and Epidemiology
- Viral Infections and Vectors
- SARS-CoV-2 and COVID-19 Research
- Microbial infections and disease research
- Amphibian and Reptile Biology
- Poxvirus research and outbreaks
- Rabies epidemiology and control
- Wildlife Ecology and Conservation
- Marine animal studies overview
- Environmental DNA in Biodiversity Studies
- Identification and Quantification in Food
- Parasite Biology and Host Interactions
- Veterinary Medicine and Surgery
- Aquaculture disease management and microbiota
- Viral gastroenteritis research and epidemiology
- Vector-borne infectious diseases
- Species Distribution and Climate Change
Wildlife Conservation Society
2015-2024
United States Department of Agriculture
2021
Smithsonian Conservation Biology Institute
2021
National Zoological Park
2021
Philadelphia Zoo
2021
Western University of Health Sciences
2021
North Carolina State University
2021
New York State College of Veterinary Medicine
2015-2021
Cornell University
2015-2021
University of Illinois Urbana-Champaign
2021
The human-animal-environment interface of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an important aspect the disease 2019 (COVID-19) pandemic that requires robust One Health-based investigations. Despite this, few reports describe natural infections in animals or directly link them to human using genomic data. In present study, we first cases SARS-CoV-2 infection tigers and lions United States provide epidemiological genetic evidence for human-to-animal transmission...
Hi-C contact maps are valuable for genome assembly (Lieberman-Aiden, van Berkum et al. 2009; Burton 2013; Dudchenko 2017). Recently, we developed Juicebox, a system the visual exploration of data (Durand, Robinson 2016), and 3D-DNA, an automated pipeline using to assemble genomes (Dudchenko Here, introduce “Assembly Tools,” new module which provides point-and-click interface heatmaps identify correct errors in assembly. Together, 3D-DNA Juicebox Assembly Tools greatly reduce cost accurately...
The global trade in wildlife has historically contributed to the emergence and spread of infectious diseases. United States is world's largest importer products, yet minimal pathogen surveillance precluded assessment health risks posed by this practice. This report details findings a pilot project establish methodology for zoonotic agents confiscated products. Initial from samples collected at several international airports identified parts originating nonhuman primate (NHP) rodent species,...
Fewer than 500 Amur tigers (Panthera tigris altaica) remain in the wild. Due to low numbers and their solitary reclusive nature, tiger sightings across range Russian Far East China are rare; of sick rarer still. Serious neurologic disease observed several wild since 2001 suggested emergence this endangered species. To investigate possibility, histology, immunohistochemistry (IHC), situ hybridization (ISH), reverse transcription-PCR (RT-PCR) were performed on tissues from 5 affected that died...
This report describes the identification and characterization of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a Malayan tiger U.S. zoo.
Abstract The 2016–2017 introduction of peste des petits ruminants virus (PPRV) into livestock in Mongolia was followed by mass mortality the critically endangered Mongolian saiga antelope and other rare wild ungulates. To assess nature population effects this outbreak among ungulates, we collected clinical, histopathologic, epidemiologic, ecological evidence. Molecular characterization confirmed that causative agent PPRV lineage IV. spatiotemporal patterns cases wildlife were similar to...
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged as the cause of a global pandemic in 2019–2020. In March 2020, New York City became epicenter United States for pandemic. On 27 Malayan tiger (Panthera tigris jacksoni) at Bronx Zoo developed cough and wheezing with subsequent inappetence. Over next week, an additional two Amur tigers altaica) same building three lions leo krugeri) separate also ill. The index case was anesthetized diagnostic workup. Physical examination...
The ability to sequence a variety of wildlife samples with portable, field-friendly equipment will have significant impacts on conservation and health applications. However, the only currently available DNA sequencer, MinION by Oxford Nanopore Technologies, has high error rate compared standard laboratory-based sequencing platforms not been systematically validated for barcoding accuracy preserved non-invasively collected tissue samples. We tested whether various sample types, methods, our...
Canine distemper virus (CDV) has recently emerged as an extinction threat for the endangered Amur tiger (Panthera tigris altaica). CDV is vaccine-preventable, and control strategies could require vaccination of domestic dogs and/or wildlife populations. However, remains controversial, which led to a focus on interventions in dogs, often assumed be source infection. Effective decision making requires understanding true reservoir dynamics, poses substantial challenges remote areas with diverse...
Prevalence and disease caused by isosporoid coccidia in passerine birds are well recognized, but confusion about the life cycles of parasites has led to taxonomic inconsistencies. In this study, we characterized segments chromosomal small large-subunit ribosomal RNA (rRNA) genes coccidial from 23 species birds, as heat shock protein 70, apicoplast rRNA, 5.8s rRNA a subgroup these animals, correlated genetic data with morphologic findings for different parasite developmental stages, host...
Abstract The Cordillera Vilcanota in southern Peru is the second largest glacierized range tropics and home to one of high‐alpine lakes, Sibinacocha (4,860 m). Here, Telmatobius marmoratus (marbled water frog), Rhinella spinulosa (Andean toad), Pleurodema marmoratum four‐eyed frog) have expanded their vertically within past century inhabit newly formed ponds created by ongoing deglaciation. These anuran populations, geographically among highest (5,200–5,400 m) recorded globally, are being...
MEPS Marine Ecology Progress Series Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsTheme Sections 493:275-289 (2013) - DOI: https://doi.org/10.3354/meps10506 Unexplained recurring high mortality of southern right whale Eubalaena australis calves at Penïnsula Valdïs, Argentina Victoria J. Rowntree1,2,3,4,*, Marcela M. Uhart1,5, Mariano Sironi1,4, Andrea Chirife1, Matias Di Martino1, Luciano La Sala1,...
Abstract We describe the first cases of natural SARS-CoV-2 infection detected in animals United States. In March 2020, four tigers and three lions at Bronx Zoo developed mild respiratory signs. RNA was by rRT-PCR secretions and/or feces from all seven affected animals; viral antibodies were their keepers. isolated or situ hybridization co-localized with cellular damage. Whole genome sequence haplotype network analyses showed infected two different strains, suggesting independent...
Respiratory infections are important causes of morbidity and mortality in reptiles; however, the causative agents only infrequently identified. Pneumonia, tracheitis esophagitis were reported a collection ball pythons (Python regius). Eight 12 snakes had evidence bacterial pneumonia. High-throughput sequencing total extracted nucleic acids from lung, esophagus spleen revealed novel nidovirus. PCR indicated presence viral RNA trachea, esophagus, liver, spleen. In situ hybridization confirmed...
Mycoplasma infections can cause significant morbidity and mortality in captive wild chelonians. As part of a health assessment endangered bog turtles (Glyptemys muhlenbergii) the northeastern US, choanal cloacal swabs from these other sympatric species, including spotted (Clemmys guttata), eastern box (Terrapene carolina carolina), wood insculpta), common snapping (Chelydra serpentina) 10 sampling sites states (US) Delaware, New Jersey, Pennsylvania, were tested by PCR for Mycoplasma. Of 108...
Canine distemper virus (CDV) has caused clinical disease and death in nondomestic felids both captive settings the wild. Outbreaks resulting high mortality rates tigers (Panthera tigris) have prompted some zoos to vaccinate for CDV. In this study, six received a recombinant canarypox-vectored CDV vaccine (1 ml s.c.) were revaccinated with 3 s.c. (mean) 39 days later. Blood collection antibody detection via serum neutralization was performed on 0, 26, 66 post–initial vaccination. No had...
Between 2003 and 2012, 605 southern right whales (SRW; Eubalaena australis) were found dead along the shores of Península Valdés (PV), Argentina. These deaths included alarmingly high annual losses between 2007 a peak number (116) in significant across years calves-of-the-year (544 [89.9%]; average = 60.4 yr(-1)). Post-mortem examination pathogen testing performed on 212 whales; 208 (98.1%) 48.0% these newborns or neonates. A known probable cause death was established only small (6.6%)...
Polycystic kidney and liver disease was present in four of six female three five male offspring born two matings between the same pair West Highland White Terriers. Clinical signs were apparent serum biochemistry analysis consistent with failure evident by 5 weeks age. Affected pups euthanatized because their disease. Renal cysts confirmed to be collecting duct origin Dolichos bifluros agglutinin lectin histochemistry, hepatic biliary origin. The clinically unaffected parents related through...
Melengestrol acetate (MGA), a potent synthetic progestin, has been used as contraceptive in zoo felids since 1975. Mammary gland carcinomas have linked to MGA treatment felids, but the histologic features of these tumors and steroid receptor expression not described. Zoo felid mammary were requested from participating zoos 1986 through 1998, 31 28 MGA-treated 3 untreated received. The evaluated on basis pattern, tumor grade, occurrence metastasis; then compared determine if differed those...
Infectious diseases have caused die-offs in both free-ranging gorillas and chimpanzees. Understanding pathogen diversity disease ecology is therefore critical for conserving these endangered animals. To determine viral free-ranging, non-habituated chimpanzees the Republic of Congo, genetic testing was performed on great-ape fecal samples collected near Odzala-Kokoua National Park. Samples were analyzed to ape species, identify individuals population, test presence herpesviruses,...
The rich diversity of the world's reptiles is at risk due to significant population declines broad taxonomic and geographic scope. Significant factors attributed these include habitat loss, pollution, unsustainable collection infectious disease. To investigate presence significance a potential pathogen on populations critically endangered bog turtles (Glyptemys muhlenbergii) as well sympatric wood (G. insculpta) spotted (Clemmys guttata) in northeastern United States, choanal cloacal swabs...
The critically endangered population of Far Eastern leopards ( Panthera pardus orientalis) may number as few 60 individuals and is at risk from stochastic processes such infectious disease. During May 2015, a case canine distemper virus (CDV) was diagnosed in wild leopard exhibiting severe neurologic disease the Russian territory Primorskii Krai. Amplified sequences CDV hemagglutinin gene phosphoprotein aligned within Arctic-like clade CDV, which includes viruses elsewhere Russia, China,...
Canine distemper virus (CDV) is a multi-host pathogen that can cause significant mortality in domestic, wild terrestrial and marine mammals. It major conservation threat some endangered species. Infection result severe respiratory disease fatal encephalitis. Diagnosis monitoring wildlife, differentiation of CDV from rabies (a life-threatening zoonotic produce similar neurologic signs), would benefit the availability portable, point-of-care (POC) diagnostic test. We therefore developed...