Colleen McCann
- Spaceflight effects on biology
- Contact Dermatitis and Allergies
- Reproductive Biology and Fertility
- Comparative Animal Anatomy Studies
- Dermatology and Skin Diseases
- COVID-19 Clinical Research Studies
- Global Public Health Policies and Epidemiology
- Ovarian function and disorders
- Health disparities and outcomes
- Heat shock proteins research
- Physiological and biochemical adaptations
- Space Science and Extraterrestrial Life
- Climate Change and Health Impacts
- Allergic Rhinitis and Sensitization
- Reproductive Health and Technologies
- Injury Epidemiology and Prevention
- Pharmacological Effects and Assays
- SARS-CoV-2 and COVID-19 Research
- Animal Virus Infections Studies
- Neural and Behavioral Psychology Studies
- Genetics, Aging, and Longevity in Model Organisms
- Neuroethics, Human Enhancement, Biomedical Innovations
Mount Sinai Medical Center
2025
Wildlife Conservation Society
2021-2025
University of North Carolina at Chapel Hill
2024-2025
University of California, Davis
2023
United States Department of Agriculture
2021
New York State College of Veterinary Medicine
2021
Cornell University
2021
University of Illinois Urbana-Champaign
2021
Chicago Zoological Society
2021
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged as the cause of a global pandemic in 2019–2020. In March 2020, New York City became epicenter United States for pandemic. On 27 Malayan tiger (Panthera tigris jacksoni) at Bronx Zoo developed cough and wheezing with subsequent inappetence. Over next week, an additional two Amur tigers altaica) same building three lions leo krugeri) separate also ill. The index case was anesthetized diagnostic workup. Physical examination...
Abstract Missions into Deep Space are planned this decade. Yet the health consequences of exposure to microgravity and galactic cosmic radiation (GCR) over years-long missions on indispensable visceral organs such as kidney largely unexplored. We performed biomolecular (epigenomic, transcriptomic, proteomic, epiproteomic, metabolomic, metagenomic), clinical chemistry (electrolytes, endocrinology, biochemistry) morphometry (histology, 3D imaging, miRNA-ISH, tissue weights) analyses using...
Protein quality control is crucial for cellular homeostasis, involving the heat shock response, ubiquitin-proteasome system, and autophagy-lysosome pathway. Central to these systems are chaperone homologs protein 70 (HSP70) cognate (HSC70), which manage folding degradation. This study investigated impact of C-terminal phosphorylation HSP70 on its interaction with co-chaperone CHIP (C-terminus HSC70 interacting protein), an E3 ligase that ubiquitinates substrates Using both cell-free...
Cardiac disease is a common cause of mortality in many primates housed zoological settings. At the Bronx Zoo, between 2007 and 2018, there were ten incidences sudden cardiac death adult male geladas (Theropithecus gelada), none which showed premonitory signs. Due to concerns occult fatal arrhythmogenic events, complete examinations performed three clinically normal, geladas. Examinations included thoracic radiographs, transthoracic echocardiograms (echo), 12-lead ECG, continuous ECG...
A complication of cancer-directed therapy that often goes undiscussed is infertility. Although guidelines recommend addressing the possibility infertility and fertility preservation approaches before initiating treatment, an internal review at our institution showed only 49% female patients had risk counseling documented. As a result, assessment communication was added into all oncology treatment plans to improve rates discussion documentation.
Past research has supported the idea that exercise is beneficial for mind and cognitive functions. Further, imaging neurotransmitter studies have shown how acute can increase white matter monoamines in brain, thus improving cognition. On this basis, it was inferred exercise, specifically long-term will improve an individual’s performance. To determine this, college-aged subjects were assessed with baseline reaction time simultaneous amplitude discrimination tests. They subsequently...
Allergic dermatitis was diagnosed in a 25-yr-old female greater one-horned rhinoceros (Rhinoceros unicornis) and her 6-yr-old offspring by skin biopsy, intradermal testing (IDST), allergen-specific serum IgE testing. Dam presented with seasonal, erosive, ulcerative affecting the face, legs, trunk starting at 6 2 yr of age, respectively. IDST performed caudal pinnal base using 61 regionally specific allergens. Specific allergen responses were detected Heska's Equine ALLERCEPT® Allergen Panel....