- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- Sarcoma Diagnosis and Treatment
- Hip disorders and treatments
- Bone health and treatments
- Cancer Cells and Metastasis
- Bone Tissue Engineering Materials
- Bone fractures and treatments
- Hip and Femur Fractures
- Knee injuries and reconstruction techniques
- Mesenchymal stem cell research
- 3D Printing in Biomedical Research
- Orthopedic Surgery and Rehabilitation
- Bone Tumor Diagnosis and Treatments
- Osteoarthritis Treatment and Mechanisms
- Management of metastatic bone disease
- Cancer Research and Treatments
- Tissue Engineering and Regenerative Medicine
- Shoulder Injury and Treatment
- Spinal Fractures and Fixation Techniques
- Cancer Diagnosis and Treatment
- Periodontal Regeneration and Treatments
- Spine and Intervertebral Disc Pathology
- Prostate Cancer Treatment and Research
Ludwig-Maximilians-Universität München
2008-2025
LMU Klinikum
2022-2024
Heinrich Heine University Düsseldorf
2024
Düsseldorf University Hospital
2024
University Hospital Münster
2024
München Klinik
2024
Queensland University of Technology
2013-2023
Klinik und Poliklinik für Orthopädie, Physikalische Medizin und Rehabilitation
2022-2023
Klinik König-Ludwig Haus
2012-2022
University of Würzburg
2011-2021
ABSTRACT The skeleton is a preferred homing site for breast cancer metastasis. To date, treatment options patients with bone metastases are mostly palliative and the disease still incurable. Indeed, key mechanisms involved in osteotropism only partially understood due to lack of suitable animal models mimic metastasis human tumor cells microenvironment. In presented study, we investigate use tissue-engineered construct develop humanized xenograft model cancer-induced murine host. Primary...
Clinical evidence indicates that an unintended increase in the medial proximal tibial angle (MPTA) can occur during slope-reducing osteotomies, which is most relevant anterior cruciate ligament (ACL) deficient knees. Therefore, purpose of this three-dimensional (3D) simulation study to assess how axial or coronal hinge axis rotation affect alignment parameters closing wedge osteotomies (ACWO). The hypothesis states a neutral (NHA) ACWO prevents changes and alignment. A 3D surgical was used...
A skin window enables noninvasive, longitudinal monitoring of cancer growth and therapy response in tissue-engineered bone mice.
This case report presents the clinical findings and management of a 32-year-old male recreational athlete who presented with ongoing knee pain for 4 months, without history trauma. The patient experienced intermittent during walking, particularly after prolonged periods sitting, exhibited positive on meniscus tests. However, he was able to participate in sports activities pain. Magnetic resonance imaging (MRI) revealed partial tear medial gastrocnemius head, confirming diagnosis....
The posterior cruciate-retaining (CR) design offers rotational freedom but risks abnormal kinematics and instability. medial pivot (MP) mimics native joint motion with a high-conformity flat lateral interface. Within clinical studies, the MP outclassed CR design, biomechanical studies are lacking. This study investigates tibiofemoral patellofemoral of both implant designs compared to kinematics. Eight fresh-frozen cadaveric knee specimens underwent total arthroplasty using designs. Testing...
Cavitary bone defects, defined as a volumetric loss of native tissue, require accurate preoperative imaging for treatment planning. While CT (computed tomography) has traditionally been the gold standard segmentation due to its superior resolution cortical bone, MRI (magnetic resonance imaging) offers unique advantages, particularly in visualizing soft tissue-bone interface. Furthermore, eliminates ionizing radiation associated with CT, making it an advantageous alternative, especially...