A5100332398- Acute Myeloid Leukemia Research
- COVID-19 Clinical Research Studies
- Stock Market Forecasting Methods
- Ferroptosis and cancer prognosis
- Neutropenia and Cancer Infections
- Blood disorders and treatments
- Pharmacology and Obesity Treatment
- Cytomegalovirus and herpesvirus research
- Landscape and Cultural Studies
- Adrenal and Paraganglionic Tumors
- Diabetes and associated disorders
- Remote Sensing in Agriculture
- Organ Transplantation Techniques and Outcomes
- Traditional Chinese Medicine Analysis
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Hepatocellular Carcinoma Treatment and Prognosis
- Long-Term Effects of COVID-19
- Biosimilars and Bioanalytical Methods
- Hair Growth and Disorders
- Acute Lymphoblastic Leukemia research
- Diabetes Treatment and Management
- Energy Load and Power Forecasting
- Neuroinflammation and Neurodegeneration Mechanisms
- Glioma Diagnosis and Treatment
- Urban and spatial planning
Third Affiliated Hospital of Sun Yat-sen University
2024
Sun Yat-sen University
2024
Northwest Institute of Mechanical and Electrical Engineering
2024
Xuzhou Medical College
2023
Beijing University of Technology
2023
Bengbu Medical College
2023
First Affiliated Hospital of Bengbu Medical College
2023
Second Affiliated Hospital of Nanjing Medical University
2023
Shanghai Jiao Tong University
2023
Tianjin Medical University
2022
Effective treatments for patients with severe COVID-19 are needed.To evaluate the efficacy of canakinumab, an anti-interleukin-1β antibody, in hospitalized COVID-19.This randomized, double-blind, placebo-controlled phase 3 trial was conducted at 39 hospitals Europe and United States. A total 454 pneumonia, hypoxia (not requiring invasive mechanical ventilation [IMV]), systemic hyperinflammation defined by increased blood concentrations C-reactive protein or ferritin were enrolled between...
Background: Lorcaserin, a novel selective 5-HT2C receptor agonist, is approved by the US Food and Drug Administration (FDA) for weight management in combination with lifestyle modification adults obesity overweight ≥ 1 weight-related comorbid condition. The safety effectiveness of lorcaserin adult patients without type 2 diabetes mellitus was established based on phase III clinical trials similar design: Behavioral Modification Lorcaserin Overweight Obesity Management (BLOOM) Second Study...
Compared with younger patients, older adults acute myeloid leukemia (AML) generally have poorer survival outcomes and less benefit from clinical trials. A recent phase 3 trial demonstrated a trend toward improved overall (OS) decitabine, hypomethylating agent, compared treatment choice of either cytarabine or supportive care (7.7 months, 95% CI: 6.2–9.2 vs 5.0 4.3–6.3, respectively) in newly diagnosed AML. The current analyses investigated prognostic factors for this examined OS responses...
Objectives: Lorcaserin is a selective 5-HT2C (5-hydroxytryptamine 2C) receptor agonist indicated for weight management. Here, we assess the impact of lorcaserin on progression from prediabetes to type 2 diabetes (T2D) and reversion euglycemia.Methods: This post hoc analysis pooled data two Phase 3 studies, BLOOM BLOSSOM (N = 6136), evaluating glycemic parameters over 52 weeks in subpopulation obese/overweight subjects with prediabetes, alternately defined by fasting plasma glucose (FPG)...
The classification of pituitary tumors is frequently updated to optimize guidance for clinical treatment based on current knowledge. To date, the World Health Organization conducts periodic expert review consensus meetings and publishes results. These include recommendations behavior more aggressive, high Ki-67 index (>3%)pituitary. A Knosp grade (>3) associated with a risk recurrence. We report an inverse relationship between labeling functional adenomas nonfunctional adenoma (Spearman...
Plant height and leaf area index (LAI) are crucial growth indicators that reflect the status of tomatoes in greenhouses, enabling accurate determinations to effectively estimate crop transpiration formulate irrigation strategies for reducing agricultural water waste. There is a need increased application related models simulate tomato indices traditional greenhouse production China. This study proposes nondestructive, real-time monitoring simulation device measuring plant index. The weight...
Aim: This is a pooled subgroup analysis of Asian patients enrolled in two Phase III confirmatory studies comparing proposed biosimilar LA-EP2006 with reference pegfilgrastim women receiving chemotherapy for breast cancer. Patients & methods: Women were randomized to (n = 90) or 84) (Neulasta®, Amgen, Inc., CA, USA) ≤6 cycles TAC chemotherapy. Primary end point was duration severe neutropenia during Cycle 1 (number consecutive days absolute neutrophil count <0.5 × 109/l) equivalence confirmed...
Objective: We conducted this study to explore the effect of oral probiotic supplementation on hair density as a primary outcome in subjects with loss and at high risk metabolic syndrome. The secondary objectives were assess effects skin barrier function,metabolic health stress responses.Methods: supplemented diets Chinese adults presenting syndrome (n = 26, male gender 38.5%, age 33.6 ± 4.5 years) multi-strain formula dosage 18.1 billion colony forming units (CFU) twice daily for 12 weeks....
Acute-on-chronic liver failure (ACLF) tends to progress rapidly with high short-term mortality. We aimed create a widely applicable, simple prognostic (WASP) score for ACLF patients.A retrospective cohort of cases recruited from three centers in China were divided into training and validation sets develop the new score. A prospective longitudinal was further validation.A total 541 included set, seven independent factors screened construct quantitative WASP-ACLF table. In set 671 cases,...
Primary liver cancer (PLC) is a common malignancy with poor survival and requires long-term follow-up. Hence, nomograms need to be established predict overall (OS) cancer-specific (CSS) from different databases for patients PLC.Data of PLC were downloaded Surveillance, Epidemiology, End Results (SEER) the Cancer Genome Atlas (TCGA) databases. The Kaplan Meier method log-rank test used compare differences in OS CSS. Independent prognostic factors determined by univariate multivariate Cox...
Introduction G-protein-coupled receptor 119 (GPR119) is emerging as a potential therapeutic target against type 2 diabetes with beneficial effects on glucose homeostasis. However, the function of GRP119 in lipotoxicity induced pancreatic beta cell apoptosis and molecular mechanism remains largely unknown. Material methods Impact GPR119 islet was evaluated INS-1 cells treated palmitate. The subsequent modulation MST1-FOXO1-Pdx1 signaling pathway pro-apoptotic caspase-3 system were determined...
Over the past two years, global stock markets have gradually recovered and new investors entered market. While there are many factors affecting prices market is changing rapidly, way to accurately predict has become focus of investors. This paper will use concept machine learning three listed companies based on different regression models (i.e., OLS, Ridge XGBoost). According analysis, OLS model very accurate in predicting prices, especially low middle price ranges. In contrast these typical...
Abstract Background Neuroblastoma (NB) is one of the most common extracranial malignancies in central nervous system, threatening children’s health. It an embryonic neural crest cell-derived pediatric solid tumor, usually resulting tumors adrenal glands or sympathetic ganglia. The clinical presentation can be quite heterogeneous, ranging from asymptomatic incidental to widespread metastases with systemic manifestations. While children diagnosed clinically stable NB completely cured, those...
Mount Kumgang, located in the middle of eastern coastal area Korean Peninsula, has been a cultural symbol this region historically. It stretches across two countries, Democratic People’s Republic Korea (DPRK) and (ROK). The former enjoys thirds total rich natural landscape relics, which is now known as Kumgang International Tourist Zone. design responds to bond both DPRK ROK people through approaches while celebrating resources Kumgang. By building tourist zone planning system based on...
Objective To investigate the value of prophylactic application polyethylene glycolated recombinant human granulocyte colony stimulating factor (PEG-rhG-CSF) in chemotherapy for patients with gynecologic malignant tumor. Methods The clinical statistics tumor hospitalized Guangdong Women’s and Children’s Hospital during from 2016 to 2018 were retrospectively analyzed. The divided into a research group control according whether applying PEG-rhG-CSF or not. baseline statistics, incidence...
Index rebalancing is a strategy that based on changes in the index's constituent equities. The takes long positions newly added equities and short stocks have been removed. Arbitrage opportunities are created because indicator institutions will buy sell deleted depending change of index. SSE380 an important for Chinese stocks. We use to study strategy. To test whether index can be successfully applied make investors profitable. tested using data from January 2011 June 2021. A total 19...