A5022394011- Parasitic Infections and Diagnostics
- Helminth infection and control
- Parasite Biology and Host Interactions
- Toxoplasma gondii Research Studies
- Vector-borne infectious diseases
- Coccidia and coccidiosis research
- Viral Infections and Vectors
- Animal Nutrition and Physiology
- Parasitic infections in humans and animals
- Herpesvirus Infections and Treatments
- Animal Behavior and Welfare Studies
- Bird parasitology and diseases
- Vector-Borne Animal Diseases
- Dermatological diseases and infestations
- Virology and Viral Diseases
- Nematode management and characterization studies
- Environmental DNA in Biodiversity Studies
- Mollusks and Parasites Studies
- Wildlife Ecology and Conservation
- Cytomegalovirus and herpesvirus research
- Study of Mite Species
- Genetic and Kidney Cyst Diseases
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Amoebic Infections and Treatments
- Virus-based gene therapy research
Leipzig University
2018-2025
Justus-Liebig-Universität Gießen
2016
Leibniz Association
2013-2014
Toxoplasma gondii is a protozoan parasite in cats that can be cause of zoonotic concern due to sheding infectious and highly resistant oocysts. Clinical toxoplasmosis rare occur with mild severe clinical signs or even fatal outcomes. T. immunoglobulin M (IgM) IgG an indicator ongoing prior infection. Information about occurrence the domestic cat population, primary concerns affected cats, potential risk factors scarce Germany. This retrospective study explored data from 174 feline patients...
To investigate the presence of neutrophil extracellular traps (NETs) in vivo by analysing intestinal sections from experimentally Eimeria bovis- and naturally arloingi-infected animals. Intestinal samples arloingi- bovis-infected animals were analysed using immunohistochemical fluorescence approach monoclonal antibodies. Classical NET components confirmed co-localization DNA being decorated with elastase histones Eimeria-infected tissue samples. Here, extrusion NETs was exclusively detected...
Radiation-attenuated intracellular parasites are promising immunization strategies. The irradiated able to invade host cells but fail fully replicate, which allows for the generation of an efficient immune response. Available radiation technologies such as gamma rays require complex shielding constructions and difficult be integrated into pharmaceutical production processes. In this study, we evaluated first time low-energy electron irradiation (LEEI) a method generate replication-deficient...
Abstract The raccoon, Procyon lotor (Carnivora: Procyonidae), is an invasive species that spreading throughout E urope, in which G ermany represents its core area. Here, raccoons mostly live rural regions, but some urban populations are already established, such as the city of K assel, or starting to build up, B erlin. objective this study was investigate Sarcoptes (Sarcoptiformes: Sarcoptidae) infections racoons these two areas and identify putative origin parasite. Parasite morphology,...
Abstract Background Ixodid ticks are important vectors for zoonotic pathogens, with Ixodes ricinus being the most in Europe. Rodents hosts of immature life stages I. and considered main reservoirs tick-borne e.g. Borrelia burgdorferi . The aim this study was to analyse prevalence as well genospecies sequence type (ST) diversity sensu lato small mammals from central Germany elaborate on influence environmental and/or individual host vector factors prevalence. Methods After species...
Rickettsiae of the spotted fever group (SFG) are zoonotic tick-borne pathogens. Small mammals important hosts for immature life stages two most common tick species in Europe, Ixodes ricinus and Dermacentor reticulatus. These vectors can be found diverse habitats with different vegetation types like grasslands forests. To investigate influence environmental individual factors on Rickettsia prevalence, this study aimed to analyse prevalence SFG rickettsiae ticks small small-scale central...
Cryptosporidiosis is a parasitic disease associated with potentially fatal diarrhea. The most used method in Cryptosporidium subtyping based on the glycoprotein gene gp60. Each infection can represent parasite population, and it important to investigate influence transmission virulence, as well any impact public health investigations. However, an easy-to-use for detection lacking.Here we report use of bioinformatic program TIDE deconvolution gp60 chromatograms. A combination single oocyst...
Chicken coccidiosis causes annual losses exceeding GBP 10 billion globally. The most pathogenic species for domestic fowls including Eimeria tenella, E. acervulina, and maxima, can lead to gastrointestinal issues ranging from mild fatal. In this study, stages of tenella freshly isolated chicken heterophils were co-cultured 180 min. These interactions analyzed using live 3D holotomographic confocal microscopy. We observed that entrapped by heterophil extracellular traps (HETs). Notably,...
Coccidiosis is an economically important gastrointestinal disease in domestic fowl. Eimeria species are the causative agents of avian coccidiosis. Current challenges management and prevention eimeriosis enhance need for research this field. Sporozoite purification a necessary step spp. vitro infection models. alternatives such as DE-52 anion exchange chromatography Percoll gradient require time resources. We present modified protocol consisting on vacuum filtration sporozoites using...
Abstract Background Toxoplasma gondii is an obligate intracellular parasite with a worldwide distribution. Congenital infection in humans and animals may lead to severe symptoms the offspring, especially brain. A suitable animal model for human congenital toxoplasmosis currently lacking. The aim of this study establish validate guinea pig as by investigating impact T. dose, duration gestational stage at on seroconversion, survival rate dams, fate DNA loads various offspring tissues organs...
Abstract Poultry coccidiosis causes considerable economical losses to the livestock industry. Eimeria parasites are responsible for this disease. On a global scale, E. acervulina and tenella amongst most common spp. infecting broilers. is commonly used as infection model in vivo vitro studies. other hand, has barely been studied under conditions. A well established widely Madin-Darby bovine kidney cell line (MDBK); however, little known regarding suitability of MDBK cells host . We infected...
Game meat is an important source of borne parasitic infections. Due to its omnivorous diet, the wild boar host zoonotic parasites such as
Abstract Background European wildcats ( Felis silvestris ) are widely distributed in Europe and a strictly protected species Germany. Lately, anthropogenic protective efforts lead to increasing numbers of southwestern Moreover, recent years the domestic cats increasing. Thus, contact between may spread zoonotic pathogens both animal species. As data on vector-borne (VBPs) from Germany limited date, objective this study was investigate presence current distribution VBPs Methods Skin spleen...
Abstract Trichomonas gallinae are parasitic flagellates of importance in wild and domestic birds. The parasite is worldwide distributed, Columbine birds its main host. Current research focuses mostly on epidemiological phylogenetic studies. However, there still a lack knowledge regarding parasite-host interaction or therapy development. Real-time PCR useful tool for diagnostic quantification gene copies determined sample. By amplification 113-bp region the 18S small subunit ribosomal RNA...