The escalating prevalence of metabolic diseases and an aging demographic has been correlated with a concerning rise in Alzheimer's disease (AD) incidence. This study aimed to access the protective effects curcumin, bioactive flavonoid from turmeric, on spatial memory, functions, regulation gut microbiome AD-induced (3xTg-AD) mice fed either normal chow diet (NCD) or high-fat high-sugar (HFHSD). Our findings revealed augmented susceptibility HFHSD-fed 3xTg-AD for weight gain memory...

As an eco-friendly alternative to the conventional anthraquinone process, electrochemical production of hydrogen peroxide (H2O2) through oxygen reduction reaction has been attracting attention. The goal this work is derive a carbon-based material from carbon dioxide (CO2) achieve high performance in H2O2 production. Doping heterogeneous element such as on catalyst mainly explored increase selectivity and activity, but little research conducted enhancing catalytic activity with oxidized boron...

Dietary interventions with bioactive compounds have been found to suppress the accumulation of senescent cells and senescence-associated secretory phenotypes (SASPs). One such compound, curcumin (CUR), has beneficial health biological effects, including antioxidant anti-inflammatory properties, but its ability prevent hepatic cellular senescence is unclear. The objective this study was investigate effects dietary CUR as an on determine benefits aged mice. We screened transcriptome that...

Plant-derived feed additives provide cost effective and environmentally friendly alternatives to antibiotics for improving fish performance in aquaculture. An 8-week feeding trial was conducted evaluate the effects of dietary ginger residue from juice extraction (GRJE) on juvenile black rockfish (Sebastes schlegelii) growth performance, antioxidant enzyme activities, resistance Streptococcus iniae infection. Juvenile (n = 450; initial weight 2.2 ± 0.01 g) were randomly distributed into 30 L...

In this study, we analyze the characteristics of fast transient drain current (ID) in IGZO-based field-effect transistors (FETs) with different composition ratios (device O: ratio 1:1:1 for In, Ga, Zn, device G: 0.307:0.39:0.303) reliable operations. Overshoot currents, which can cause degradation, are caused by transients and attributed to trapping electrons energy band. As lateral electric field (Elat) IGZO channel is increased, overshoot difference (ΔIOS) increased both devices. It also...

The aim of the current study is to investigate effects spray dry powders Curcuma longa containing 40% curcumin (CM-SD), as a new aqueous formula, on sarcopenia in chronic forced exercise executed 10 month old ICR mice. CM-SD (80 and 40 mg/kg) increased calf thicknesses strengths, total body protein amounts, muscle weights both gastrocnemius soleus muscles. mRNA expressions regarding growth synthesis were induced, while those degradation significantly declined treatment. decreased serum...

Cellular senescence is defined as an irreversible cell cycle arrest accompanied by morphological and physiological alterations during aging. Red ginseng (RG), processed from fresh (

A seven-week feeding trial was conducted to evaluate the effects of vegetable and fruit juice processing by-product feed additives on juvenile black rockfish (Sebastes schlegelii) growth, utilization, non-specific immune responses, resistance Vibrio harveyi. Juvenile (n = 1050) were randomly distributed into 300 L circular tanks (50 fish per tank). Seven experimental diets prepared in triplicate. The supplemented with 1% garlic, ginger, blueberry, tomato, onion, or yacon powders, referred as...

Cellular senescence, one of the hallmarks aging, refers to permanent cell cycle arrest and is accelerated during aging process. Black ginseng (BG), prepared by a repeated steaming drying process nine times from fresh (Panax C.A. Meyer), garnering attention for herbal medicine due its physiological benefits against reactive oxygen species (ROS), inflammation, oncogenesis, which are common cues induce aging. However, key nodules in cellular senescence regulated BG supplementation has not been...

This study examined the efficacy of standardized Smilax china L. root extract (SSCR) containing chlorogenic acid on detoxifying nicotine from tobacco smoke condensate (TSC) in vitro and vivo. Chlorogenic is an identified bioactive component SSCR by ultraperformance liquid chromatography/photodiode array/electrospray ionization/mass spectroscopy (UPLC/PDA/ESI/MS). HepG2 liver cells A549 lung were carried for measuring ROS antioxidant enzymes. Sprague-Dawley rats treated with intratracheal...

We evaluated effects of dietary lipid level on growth performance, feed utilization, fatty acid composition, plasma chemistry, and antioxidant responses in juvenile walleye pollock (Gadus chalcogrammus). Two-hundred forty averaging 4.4 g weight were randomly distributed between 12 400-L flow-through circular tanks (20 fish per tank). Fish fed four isonitrogenous experimental diets with crude levels 8.1%, 12.6%, 16.7%, or 20.8% for 8 weeks. Each diet was assigned to three tanks, the hand-fed...

The purpose of the current study was to investigate antioxidant and anti-inflammatory effects spray dry powder containing 40% curcumin (CM-SD) in C2C12 myoblast cells. CM-SD increased DPPH radical scavenging activity a dose-dependent manner, up 30 μg/mL did not express cytotoxicity Exposure hydrogen peroxide (H2O2) drastically decreased viability cells, but pre-treatment significantly cell (p < 0.01). transactivated nuclear factor erythroid-2-related 2 (Nrf2)-dependent luciferase manner...

The global prevalence of visual impairment due to diseases and accidents continues increase. Visually impaired individuals rely on their auditory tactile senses recognize surrounding objects. However, accessible public facilities such as pavements signs are installed only in limited areas globally, visually use assistive devices canes or guide dogs, which have limitations. In particular, the not equipped face unexpected situations by themselves while walking. Therefore, these becoming a...

The purpose of the current study was to observe anti-diabetic and anti-obesity effects blue honeysuckle (BH; Lonicera caerulea L.) extracts on obese diabetic mice. BH dose-dependently significantly inhibited abnormal endocrine pancreas histopathological changes. Moreover, favorable non-alcoholic fatty liver disease, nephropathy, hyperlipidemia refinement activities in were shown be dose dependent. Particularly, extract 200 mg/kg showed modulatory PPAR γ AMPK hepatic adipose tissues as...

The impacts of onion peel and<italic>Dendropanax morbifera</italic>, on the digestive recovery, intestinal absorption, and pharmacokinetics GT epicatechins were studied.

An 8-week feeding trial was conducted to evaluate the effects of various dietary levels garlic juice processing waste (GJPW) on growth, feed utilization, digestive and antioxidant enzyme activity, growth- antioxidant-related gene expression, resistance Streptococcus iniae infection juvenile black rockfish (Sebastes schlegelii). A total 450 were randomly distributed into 30 L rectangular tanks (30 fish per tank). Five experimental diets prepared in triplicate. The fed supplemented with GJPW...

Abstract BACKGROUND Methylcellulose has been applied as a primary binding agent to control the quality attributes of plant‐based meat analogues. H owever, great deal effort made search for hydrocolloids replace methylcellulose because increasing awareness clean labels. In this study, machine learning framework was proposed in order describe and predict flow behavior six hydrocolloid solutions, predicted viscosities were correlated with textural features their corresponding RESULTS Different...

To investigate the effect of retinoids, such as retinol (ROL), retinal (RAL), and retinyl palmitate (RP), on epidermal integrity, skin deposition, bioconversion to retinoic acid (RA). 3-D human equivalent model (EpiDermFT™) was used. Epidermal cellular integrity measured by TEER values significantly higher for a topical treatment ROL RAL than RP (p < 0.05). The deposition (μM) approximately 269.54 ± 73.94 211.35 20.96, respectively, greater that (63.70 37.97) over 2 h incubation. Spectral...