A5053404486- Cancer Immunotherapy and Biomarkers
- Antiplatelet Therapy and Cardiovascular Diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cancer Genomics and Diagnostics
- Syphilis Diagnosis and Treatment
- Cervical Cancer and HPV Research
- Lipoproteins and Cardiovascular Health
- Atrial Fibrillation Management and Outcomes
- Neuroscience and Neural Engineering
- Liver Disease Diagnosis and Treatment
- Lung Cancer Research Studies
- COVID-19 and Mental Health
- Venous Thromboembolism Diagnosis and Management
- HIV-related health complications and treatments
- Surgical Simulation and Training
- Gut microbiota and health
- Neuroendocrine Tumor Research Advances
- Salivary Gland Tumors Diagnosis and Treatment
- Reconstructive Facial Surgery Techniques
- Acute Myocardial Infarction Research
- Pancreatic and Hepatic Oncology Research
- Endometrial and Cervical Cancer Treatments
- Simulation-Based Education in Healthcare
- Diet and metabolism studies
- Healthcare professionals’ stress and burnout
Capital Medical University
2011-2025
Anhui Medical University
2010-2025
Beijing Institute of Neurosurgery
2024-2025
Beijing Tian Tan Hospital
2023-2024
Nanjing Medical University
2022-2024
University of Nottingham
2024
University of California, San Francisco
2024
Fujian Medical University
2018-2023
Fujian Provincial Cancer Hospital
2020-2023
Third People's Hospital of Hefei
2022-2023
Stemness and chemoresistance contribute to cervical cancer recurrence metastasis. In the current study, we determined relevant players role of N6-methyladenine (m6A) RNA methylation in progression.The roles m6A centromere protein K (CENPK) were analyzed using bioinformatics analysis. Methylated immunoprecipitation was adopted detect modification CENPK mRNA. Human clinical samples, cell lines, xenografts used for analyzing gene expression function. Immunofluorescence staining tumorsphere...
The aim of this study was to investigate whether the personality traits intern nursing students could serve as valid predictors their psychological status and clinical decision making. Additionally, we aimed understand state during regular epidemic prevention control stage COVID-19.This designed a cross-sectional survey. A total 181 involved in placements participated study. Participants provided relevant data by completing Big Five Inventory-44, Self-Rating Anxiety Scale, Perceived Stress...
ABSTRACT Aim To assess risk profiles and pathways for incident type 2 diabetes by age at onset. Materials Methods Based on the Kailaun study, 92,020 participants without were enrolled classified into four age‐onset groups as < 55, 55 to 65, 65 75, ≥ 75 years. Clinical factors serum biomarkers examined. Cox regression Bayesian network analysis performed. Results Of clinical factors, metabolic syndrome had highest hazard ratio [HR] onset any age, ranging from 4.17; 95% confidence interval...
Sarcopenia and obesity, two prevalent health conditions, often coexist exacerbate each other's impact, increasing the risk of chronic diseases mortality. This dual condition is termed "sarcopenic obesity." The correlation between oxidative stress (OS) sarcopenia or obesity was established, balance score (OBS) can serve as an indicator overall dietary lifestyle-related OS exposure within individual. Prior reports have not addressed relationship OBS sarcopenic in adults under 60. study...
ABSTRACT Schwannoma surgeries pose a significant risk of postoperative neurological impairment. While intraoperative neuromonitoring (IONM) has improved surgical outcomes, it offers an indirect assessment neural structures and functions. However, during the surgeries, is not feasible to achieve comprehensive visualization nerves. To address this limitation, we introduced multi‐channel flexible microelectrode array (FMEA) characterized by its exceptional resolution, consistent conductivity,...
Previous studies have shown that remnant cholesterol (RC) was associated with cardiovascular disease (CVD). The study aim to identify the association of RC and discordance between lipoprotein (LDL-C) CVD. Data obtained from Kailuan study. calculated as non high-density minus LDL-C. Discordant LDL-C were defined by percentile difference clinical cutoff points. Cox proportional hazard models used explore Total 96,769 participants inclued, median age 51.61 years, 79.56% male. There a...
ABSTRACT Background: Previous studies have thoroughly investigated the prevalence and risk factors for completed suicide. In marked contrast is lack of a better understanding attempted suicide in elderly. The aim this study was to estimate elderly examine associated factors. Methods: Using multi-stage cluster sampling approach, cross-sectional survey 8,399 house-dwelling residents conducted Shanghai, China. Results: two-week 0.75%. bivariate analysis, having no caregivers, depressive,...
Abstract Nesfatin‐1, a newly discovered adipokine derived from nucleobindin‐2 (NUCB2), has been described as new prognostic marker in cancers. This study aimed to explore the functional role of NUCB2/nesfatin‐1 cell proliferation, migration and invasion gastric carcinoma (GC). The expressions GC tissues normal adjacent (NATs) were compared, effect inhibition on migration, epithelial‐mesenchymal transition (EMT) line SGC‐7901 was investigated. Cell transfection conducted inhibit by short...
The Ticagrelor or Clopidogrel with Aspirin in High-Risk Patients Acute Nondisabling Cerebrovascular Events II (CHANCE-2) trial showed that among Chinese patients minor ischemic stroke transient attack (TIA) who were carriers of
Insulin resistance coexist with many metabolic disorders, whether these disorders were promotors or pathway-factors for the association of insulin and cardiovascular disease (CVD) remained unclear. We aimed to investigate pathways related elevated triglyceride-glucose (TyG) index through TyG occurrence CVD in Chinese adults. A total 96,506 participants enrolled from Kailuan study. Bayesian network model max-min hill climbing algorithm maximum likelihood estimation was applied identify...
Objective To investigate the clinical value of renal perfusion imaging in patients with aortic dissection (AD) using 320-row computed tomography (CT), and to determine relationship between CT various factors dissection. Methods Forty-three AD who underwent before operation were prospectively enrolled this study. Diagnosis was confirmed by transthoracic echocardiography. Blood flow (BF) bilateral measured analyzed. signs relation type AD, number entry tears false lumen thrombus observed...
This study aims to describe the unique characteristics of absorption fever in patients with a hematoma after percutaneous renal biopsy (PRB) and distinguish it from secondary infection hematoma. We retrospectively studied 2639 biopsies native kidneys. compared clinical between 2 groups: complication group (gross hematuria and/or perirenal hematoma) no group. The axillary temperature who presented was measured at 06:00, 10:00, 14:00, 18:00. onset duration highest body were recorded....
To study the effect of mindfulness based cognitive therapy on mental health and quality life breast cancer patients. A total 84 patients who underwent surgical resection in department surgery our hospital from August 2017 to 2018 were selected. The randomly divided into intervention group (n=42) control (n=42). received an 8 w training, while only routine nursing during this period. After 8th w, same training program, changes two groups evaluated after 12 intervention. Compared with group,...
Diabet. Med. 29, 501–505 (2012) Abstract Aims To assess the efficacy of using magnetic resonance imaging measurements retinal oxygenation response to detect early diabetic retinopathy in patients with Type 2 diabetes. Methods Magnetic was conducted during 100% oxygen inhalation diabetes either no ( n = 12) or mild moderate background 12), as well healthy control subjects 12). Meanwhile, changes were measured. Results In group, levels increased slowly inhalation. contrast, they more quickly...
Understanding germline and somatic status in patients with gynecologic cancers could improve risk assessment guide therapeutic decision-making.
<b><i>Background:</i></b> Effective antiretroviral therapy extends the survival of patients with human immunodeficiency virus (HIV)/acquired immune deficiency syndrome, but these remain at higher risk for heart diseases compared general population. Previous studies have suggested that HIV-1 glycoprotein 120 (gp120) may be associated disease. However, underlying mechanisms by which gp120-mediated myocardial injury occurs unknown....
The current study investigated the psychological well-being and coping mechanisms of care home staff during coronavirus disease 2019 (COVID-19) lockdown. Among 147 members, 21.8%, 24.5%, 12.9% reported depression, anxiety, stress, respectively. results structural equation modeling showed that self-efficacy strategies had direct effects on well-being. In paths from self-perceived caregiving to well-being, positive played mediating roles independently together, social support a role together...