Mandy X. Hu

ORCID: 0000-0002-4496-8772
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About
Contact & Profiles
Research Areas
  • Heart Rate Variability and Autonomic Control
  • Blood Pressure and Hypertension Studies
  • Cardiac Health and Mental Health
  • Stress Responses and Cortisol
  • Non-Invasive Vital Sign Monitoring
  • Mental Health Research Topics
  • Eating Disorders and Behaviors
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Cardiac electrophysiology and arrhythmias
  • Cognitive Abilities and Testing
  • Sex work and related issues
  • Personality Disorders and Psychopathology
  • Transcranial Magnetic Stimulation Studies
  • Cardiovascular Disease and Adiposity
  • Medical Imaging Techniques and Applications
  • Radiomics and Machine Learning in Medical Imaging
  • Child and Adolescent Psychosocial and Emotional Development
  • Atherosclerosis and Cardiovascular Diseases
  • Travel-related health issues
  • Adipokines, Inflammation, and Metabolic Diseases
  • Digital Mental Health Interventions
  • Mental Health Treatment and Access
  • Functional Brain Connectivity Studies
  • Cancer, Hypoxia, and Metabolism
  • Dementia and Cognitive Impairment Research

Vrije Universiteit Amsterdam
2019-2023

Amsterdam University Medical Centers
2019-2023

Amsterdam Neuroscience
2022-2023

GGZ inGeest
2020

Amsterdam UMC Location Vrije Universiteit Amsterdam
2017-2018

Amsterdam Public Health
2016

Université Paris-Sud
2013

Millennium Engineering and Integration (United States)
2007

Worldwise Travellers Health & Vaccination Centres
1993

Antidepressant medication and running therapy are both effective treatments for patients with depressive anxiety disorders. However, they may work through different pathophysiological mechanisms could differ in their impact on physical health. This study examined effects of antidepressants versus mental health.According to a partially randomized patient preference design, 141 depression and/or disorder were or offered preferred 16-week treatment: antidepressant (escitalopram sertraline)...

10.1016/j.jad.2023.02.064 article EN cc-by Journal of Affective Disorders 2023-02-23

ABSTRACT Objectives It remains unclear whether depressive and anxiety disorders are associated with hyporeactivity or hyperreactivity of the autonomic nervous system (ANS) deviant reactivity occurs in all types stressors. This study compared ANS people current remitted depression/anxiety healthy controls during two stress conditions. Methods From Netherlands Study Depression Anxiety, data 804 individuals depression/anxiety, 913 466 (mean age = 44.1 years; 66.4% female) were available. Two...

10.1097/psy.0000000000000313 article EN Psychosomatic Medicine 2016-02-24

Background Depression and anxiety may unfavorably impact on cardiac autonomic dysregulation. However, it is unclear whether this relationship results from a causal effect or be attributable to confounding factors. We tested the between depression with heart rate (HR) variability (HRV) across 9-year follow-up (FU) period investigated possible by antidepressant use genetic pleiotropy. Methods Data (no. of observations = 6,994, 65% female) were obtained longitudinal Netherlands Study Anxiety,...

10.1002/da.22966 article EN Depression and Anxiety 2019-10-17

Understanding the association between autonomic nervous system [ANS] function and brain morphology across lifespan provides important insights into neurovisceral mechanisms underlying health disease. Resting-state ANS activity, indexed by measures of heart rate [HR] its variability [HRV] has been associated with morphology, particularly cortical thickness [CT]. While findings have mixed regarding anatomical distribution direction associations, these inconsistencies may be due to sex age...

10.1111/psyp.13688 article EN cc-by-nc Psychophysiology 2020-10-10

Objective To research the knowledge of AIDS and other sexually transmitted diseases among young Australian tourists to Thailand, their intended sexual behaviour Design setting: A cross-sectional survey by anonymous, self-administered questionnaire, persons seeking pre-travel medical advice in private clinics five cities. Participants: 213 consecutive patients travelling Thailand without a spouse or partner. Results: Only 34% sample reported definite intention not have sex Thailand. Regarding...

10.5694/j.1326-5377.1993.tb121868.x article EN The Medical Journal of Australia 1993-05-01

In social environments, choosing between multiple rewards is modulated by the uncertainty of situation. Here, we compared how mice interact with a conspecific and they use acoustic communication during this interaction in three chambers task (no threat was possible) Social Interaction Task, SIT (uncertain situation as two freely). We further manipulated motivational state to see rank natural such contact, food, novelty seeking. previously showed that beta2-subunit containing nicotinic...

10.3389/fnhum.2013.00468 article EN cc-by Frontiers in Human Neuroscience 2013-01-01

Autonomic nervous system (ANS) imbalance has been cross-sectionally associated with inflammatory processes. Longitudinal studies are needed to shed light on the nature of this relationship. We examined cross-sectional and bidirectional prospective associations between cardiac autonomic measures markers.Analyses were conducted baseline (n = 2823), 2-year 2099), 6-year 1774) data from Netherlands Study Depression Anxiety. To compare pattern results, analyses ANS (during sleep, leisure time,...

10.1097/psy.0000000000000589 article EN Psychosomatic Medicine 2018-05-09

Objectives: Cardiac repolarization may be affected by psychiatric disorders and/or antidepressant use, but evidence for this is inconclusive. This study examined the relationship between depressive and anxiety disorder use of antidepressants with T-wave amplitude (TWA) QT-interval. Methods: Data was obtained from Netherlands Study Depression Anxiety (n=1383). Depression/anxiety diagnosed DSM-IV based Composite International Diagnostic Interview. The tricyclic (TCAs), selective serotonin...

10.3389/fnins.2018.00375 article EN cc-by Frontiers in Neuroscience 2018-06-05

Understanding the association between autonomic nervous system [ANS] function and brain morphology across lifespan provides important insights into neurovisceral mechanisms underlying health disease. Resting state ANS activity, indexed by measures of heart rate [HR] its variability [HRV] has been associated with morphology, particularly cortical thickness [CT]. While findings have mixed regarding anatomical distribution direction associations, these inconsistencies may be due to sex age...

10.31219/osf.io/btjpw preprint EN 2018-04-03

e21088 Background: Tumor hypoxia is considered to be an independent predictor of poor prognosis, as well associated with increased likelihood local recurrence and distant metastasis. The study investigated the prognostic effect pretherapy 18F-Fluoroerythronitroimidazole (18F-FETNIM) integrated positron emission tomography computed (PET/CT) on survival analyzed whether 18F-FETNIM uptake tumor tissue could predict metastasis in non-small cell lung cancer (NSCLC). Methods: Twenty patients...

10.1200/jco.2010.28.15_suppl.e21088 article EN Journal of Clinical Oncology 2010-05-20

Background: Macrophages play a central role in atherosclerotic plaque formation. The CC chemokine receptor 2 (CCR2), expressed on the surface of circulating monocytes, and its ligand MCP-1 (CCL2), are present plaques may critical part endothelial monocyte recruitment activation. MLN1202 is humanized monoclonal antibody with high specificity to CCR2, which interrupts binding CCR2. being developed for treatment immune mediated diseases. Hypothesis: We tested hypothesis that significantly...

10.1161/circ.116.suppl_16.ii_171 article EN Circulation 2007-10-16
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