Xiaokun Liu

ORCID: 0000-0002-4889-8361
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About
Contact & Profiles
Research Areas
  • Plant-Microbe Interactions and Immunity
  • Legume Nitrogen Fixing Symbiosis
  • Plant Gene Expression Analysis
  • Plant Pathogenic Bacteria Studies
  • Plant Molecular Biology Research
  • Plant Virus Research Studies
  • Plant biochemistry and biosynthesis
  • Chromosomal and Genetic Variations
  • Postharvest Quality and Shelf Life Management
  • Plant Parasitism and Resistance
  • MicroRNA in disease regulation
  • Polysaccharides and Plant Cell Walls
  • Growth and nutrition in plants
  • Microbial Community Ecology and Physiology
  • Aquaculture Nutrition and Growth
  • Silicon Effects in Agriculture
  • Plant Physiology and Cultivation Studies
  • Plant Stress Responses and Tolerance
  • Plant Growth Enhancement Techniques
  • Physiological and biochemical adaptations
  • Circular RNAs in diseases
  • Environmental and Agricultural Sciences
  • interferon and immune responses
  • Transgenic Plants and Applications
  • Pluripotent Stem Cells Research

Guangdong Ocean University
2023-2025

University of Chinese Academy of Sciences
2024

Beijing Institute of Genomics
2024

Chinese Academy of Sciences
2018-2024

Shanghai Center For Bioinformation Technology
2024

Tianjin People's Hospital
2024

Xian Yang Central Hospital
2024

Lushan Botanical Garden
2022-2024

John Innes Centre
2017-2023

Umeå Plant Science Centre
2021-2023

RNA interference (RNAi) in plants can move from cell to cell, allowing for systemic spread of an antiviral immune response. How this cell-to-cell silencing is regulated currently unknown. Here, we describe that the C4 protein Tomato yellow leaf curl virus inhibit intercellular RNAi. Using viral as a probe, have identified receptor-like kinase (RLK) BARELY ANY MERISTEM 1 (BAM1) positive regulator movement RNAi, and determined BAM1 its closest homolog, BAM2, play redundant role process....

10.1073/pnas.1715556115 article EN Proceedings of the National Academy of Sciences 2018-01-23

The plasma membrane (PM) is composed of heterogeneous subdomains, characterized by differences in protein and lipid composition. PM receptors can be dynamically sorted into domains to underpin signaling response extracellular stimuli. In plants, the plasmodesmal a discrete microdomain that hosts specific responses. We exploited independence this domain investigate how independently integrate signal triggers responses across cell. Focusing on chitin signaling, we found require LysM receptor...

10.1073/pnas.1907799117 article EN cc-by Proceedings of the National Academy of Sciences 2020-04-13

H5N1 influenza A virus (IAV) causes severe respiratory diseases and high mortality rates in animals humans. MicroRNAs are being increasingly studied to evaluate their potential as therapeutic entities combat viral infection. However, mechanistic studies delineating the roles of microRNAs regulating host-H5N1 interactions remain scarce. Here, we performed microRNA microarray analysis using A549 human lung epithelial cells infected with a highly pathogenic avian virus. The expression profile...

10.1038/srep14991 article EN cc-by Scientific Reports 2015-10-09

The secondary walls of angiosperms contain large amounts glucuronoxylan that is thought to be covalently linked lignin via ester bonds between 4-O-methyl-α-d-glucuronic acid (4-O-Me-GlcA) moieties in and alcohol groups lignin. This linkage proposed hydrolysed by glucuronoyl esterases (GCEs) secreted wood-degrading fungi. We report effects overexpression a GCE from the white-rot basidiomycete Phanerochaete carnosa, PcGCE, hybrid aspen (Populus tremula L. x tremuloides Michx.) on wood...

10.1016/j.phytochem.2014.06.002 article EN cc-by-nc-nd Phytochemistry 2014-07-02

Peptidoglycans (PGNs) are immunogenic bacterial surface patterns that trigger immune activation in metazoans and plants. It is generally unknown how complex structures such as PGNs perceived by plant pattern recognition receptors (PRRs) whether host hydrolytic activities facilitate decomposition of matrices generation soluble PRR ligands. Here we show Arabidopsis thaliana, upon infection or exposure to microbial patterns, produces a metazoan lysozyme-like hydrolase (lysozyme 1, LYS1). LYS1...

10.7554/elife.01990 article EN cc-by eLife 2014-06-23

Abstract Background There is a growing interest in Jatropha curcas L. (jatropha) as biodiesel feedstock plant. Variations its morphology and seed productivity have been well documented. However, there the lack of systematic comparative evaluation distinct collections under same climate agronomic practices. With several reports on low genetic diversity jatropha collections, uncertainty contribution to morphology. Result In this study, five populations plants collected from China (CN),...

10.1186/1471-2229-10-259 article EN cc-by BMC Plant Biology 2010-11-23

Light is one of the regulating factors in marine environment, playing a crucial role growth, development, and metabolism benthic shellfish. To better understand light regulatory Babylonia areolata growth we used multivariate experimental design (light color variables: blue, white, green; intensity 2, 4, 8, 16, 32 μmol·m-2·s-1) to analyze effects environment on adult B. performance, energy enzyme activity glycogen content. Under same color, body weight rate at 8 16 μmol·m-2·s-1 was...

10.2139/ssrn.5090872 preprint EN 2025-01-01

Paeonia qiui is a wild species of tree peony native to China. Its leaves are purplish red from the bud germination flowering stage, and anthocyanin main pigment in leaves. However, synthesis regulation mechanism remains unclear. In this study, an R2R3-MYB, PqMYB113 was identified P. qiui. Phylogenetic analysis revealed that clustered with Liquidambar LfMYB113 grape VvMYBA6. Subcellular location showed located cell nucleus. The transient reporter assay suggested transcriptional activator....

10.3389/fpls.2021.810990 article EN cc-by Frontiers in Plant Science 2022-01-12

Paeonia qiui is a wild tree peony native to China. Its leaves show clear purple-red color from the germination flowering stage, and it has high leaf-viewing value. A MYB transcription factor gene, designated as PqMYB4, was isolated of P. based on transcriptome datas. The full-length cDNA PqMYB4 693 bp, encoding 230 amino acids. Sequence alignment phylogenetic analysis revealed that R2R3-MYB clustered with AtMYB4 in Arabidopsis thaliana. Moreover, contained C1 motif, an EAR repression motif...

10.3390/ijms21165878 article EN International Journal of Molecular Sciences 2020-08-16

Summary Wood is the most important repository of assimilated carbon in biosphere, form large polymers (cellulose, hemicelluloses including glucuronoxylan, and lignin) that interactively a composite, together with soluble extractives phenolic aliphatic compounds. Molecular interactions among these compounds are not fully understood. We have targeted expression fungal α‐glucuronidase to wood cell wall aspen ( Populus tremula L. × tremuloides Michx.) Arabidopsis thaliana (L.) Heynh), decrease...

10.1111/nph.18712 article EN cc-by-nc-nd New Phytologist 2023-01-05

In plants, plasmodesmata establish cytoplasmic continuity between cells to allow for communication and resource exchange across the cell wall. While plant pathogens use as a pathway both molecular physical invasion, benefits of invasion (cell-to-cell movement pathogen effectors) are poorly understood. To methodology identification characterization cell-to-cell mobility effectors, we performed quantitative live imaging-based screen candidate effectors fungal Colletotrichum higginsianum. We...

10.1094/mpmi-05-23-0052-ta article EN cc-by-nc-nd Molecular Plant-Microbe Interactions 2023-11-09

Abstract The plasma membrane (PM) that lines plasmodesmata has a distinct protein and lipid composition, underpinning specific regulation of these connections between cells. plasmodesmal PM can integrate extracellular signals differently from the cellular PM, but it is not known how this specificity established or single stimulus trigger independent signalling cascades in neighbouring domains. Here we have used fungal elicitor chitin to investigate signal integration responses at PM. We...

10.1101/611582 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2019-04-17

Human umbilical cord mesenchymal stem cells (hUMSCs) belong to a multipotent cell population. Transplantation of icariin (ICA)-treated hUMSCs have better tissue repairing function in chronic liver injury. This study was investigate whether the tissue-repairing effects and migration after ICA treatment were regulated by circular RNAs (circRNAs). used treat vitro for 1 week expression profiles circRNAs generated using RNA sequencing. Differentially expressed intervention screened. Gene...

10.1097/md.0000000000037549 article EN cc-by-nc Medicine 2024-03-22

The proximity ligation-based Hi-C and derivative methods are the mainstream tools to study genome-wide chromatin interactions. These often fragment genome using enzymes functionally irrelevant interactions per se, restraining efficiency in identifying structural features underlying regulatory elements. Here we present Footprint-C, which yields high-resolution contact maps built upon intact genuine footprints protected by transcription factor (TF) binding. When analyzed at one-dimensional...

10.1038/s41467-024-55403-7 article EN cc-by-nc-nd Nature Communications 2024-12-30

Abstract Multicellular organisms require dynamic communication between cells, tissues and organs to integrate responses external internal signals. In plants, cell-to-cell relies in part on plasmodesmata, which connect adjacent cells allow the exchange of signals resources. Upon infection by pathogens, plants act isolate infected from non-infected closing plasmodesmata but pathogens can suppress this defence maintain an open state. To address question what a pathogen might gain keeping open,...

10.1101/2022.01.24.477405 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2022-01-24

Summary Multicellular organisms exchange information and resources between cells to co-ordinate growth responses. In plants, plasmodesmata establish cytoplasmic continuity allow for communication resource across the cell wall. Some plant pathogens use as a pathway both molecular physical invasion. However, benefits of invasion (cell-to-cell movement pathogen effectors) are poorly understood. To begin investigate this identify which effectors cell-to-cell mobile, we performed live...

10.1101/2021.01.13.426415 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2021-01-13

ABSTRACT RNA interference (RNAi) in plants can move from cell to cell, allowing for systemic spread of an anti-viral immune response. How this cell-to-cell silencing is regulated currently unknown. Here, we describe that the C4 protein Tomato yellow leaf curl virus has ability inhibit intercellular RNAi. Using viral as a probe, have identified receptor-like kinase (RLK) BARELY ANY MERISTEM 1 (BAM1) positive regulator movement RNAi, and determined BAM1 its closest homologue, BAM2, play...

10.1101/180380 preprint EN cc-by-nc bioRxiv (Cold Spring Harbor Laboratory) 2017-08-24
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