A5101715240- Reproductive Biology and Fertility
- Ovarian function and disorders
- Prenatal Screening and Diagnostics
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive Health and Technologies
- Reproductive System and Pregnancy
- Ectopic Pregnancy Diagnosis and Management
- Endometriosis Research and Treatment
- Genomic variations and chromosomal abnormalities
- Metalloenzymes and iron-sulfur proteins
- Gestational Trophoblastic Disease Studies
- Telomeres, Telomerase, and Senescence
- COVID-19 Impact on Reproduction
- Methane Hydrates and Related Phenomena
- Kruppel-like factors research
- Pharmacological Effects and Toxicity Studies
- Sperm and Testicular Function
- Intraperitoneal and Appendiceal Malignancies
- Uterine Myomas and Treatments
- Gynecological conditions and treatments
- Microtubule and mitosis dynamics
- Genetic and Kidney Cyst Diseases
- Pluripotent Stem Cells Research
- Fetal and Pediatric Neurological Disorders
- Cerebrovascular and genetic disorders
Northwest Women's and Children's Hospital
2024
Shanxi Medical University
2006-2023
Taiyuan Maternity and Child Care Hospital
2015-2022
Shanxi Provincial Children's Hospital
2019
Creative Commons
2017
Boston Children's Hospital
2014
Peking University
2005-2006
Peking University First Hospital
2005
Surplus oocytes in assisted reproduction treatment cycles could be saved and donated to other couples. ICSI is usually performed for that have been stored frozen, considering possible exocytosis of cortical granules (CG). The unavoidability merits further study.We used a slow method freeze excess from infertile After thawing, were fertilized by either IVF or according semen parameters. Some examined CG.Twenty-eight couples cryopreserved proportion their 12 thawed oocytes. Three own oocytes,...
Background With the development of embryo freezing and warming technology, frozen-thawed transfer (FET) has been widely utilized. However, studies investigating association between cryopreservation duration FET outcomes are limited controversial, previous did not conduct stratification analyses based on demographic or clinical characteristics. Methods This multicenter retrospective study included 17,826 women who underwent their first following freeze-all strategy during period from January...
In the present study, we retrospectively recruited 340 patients who underwent spontaneous abortions to investigate chromosomal abnormalities of conception products in first trimester. We also performed a relevant analysis clinical factors. Of these patients, 165 had with abnormalities, including 135 aneuploidies, 11 triploidies, 10 complex and 9 segmental aneuploidies. The most common abnormal chromosomes were chromosome 16 embryo-transfer group sex natural-conception group. all analyzed...
Embryo chromosomal abnormalities are considered as the main cause of low pregnancy rate for in vitro fertilization (IVF). Recently, a new metric success assisted reproductive technology, that is, ability to achieve at least 1 euploid blastocyst transfer, has been brought into focus among clinicians. Our study aimed investigate effects different factors on euploidy blastocysts undergoing IVF and preimplantation genetic testing (PGT). This retrospective observational included 493 cycles...
We investigated the potential of next-generation sequencing (NGS) as an alternative method for preimplantation genetic testing monogenic disease (PGT-M) with human leukocyte antigen (HLA) matching and noninvasive prenatal diagnosis follow-up. The case involved parents who were carriers Fanconi anemia complementation group G (FANCG) 260delG mutation. After clinical PGT using conventional short tandem repeat mutation analysis, two euploid disease-free embryos transferred, resulting in a twin...
Abstract Background To investigate the interchromosomal effect (ICE) in chromosome translocation carriers. Methods Data on preimplantation genetic testing aneuploidy and structural rearrangements (translocation) were retrospectively collected classified into a reciprocal group, Robertsonian group control group. According to carrier's gender age, all cases underwent further subgroup difference analysis of de novo abnormal embryo rates number chromosomes involved embryos. Results Among 283...
e19691 Background: Pain relief is often unsatisfied in metastatic bone pain despite the availability of strong opioids, and some pts can not bear severe opioids side effects. Our trial to determine whether adding oxycodone 5 mg/acetaminophen 325 mg combination tablet on time could improve already receiving opioids. Methods: Inclusion criteria were: Bone cancer with definite iconography diagnosis; NRS (0 no pain, 10 worst pain) intensity ≥4; stable dose for at least 72 hours; KPF score≥50....
To investigate the effects of chromosome polymorphism on clinical outcomes in vitro fertilization/embryo transfer (IVF/ET)-assisted reproductive technology.The case data 2740 patients treated between January 2018 and 2019 were retrospectively analyzed. The organized into two groups: a group control group. In (n = 81), one or both parents characterized by chromosomal polymorphism; 2659), had normal karyotyping. primary included pregnancy rate (clinical fresh cycles number cycles/number embryo...
Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a life-threatening infectious that has become global pandemic.This study aimed to explore effects of SARS-CoV-2 inactivated vaccine on outcome frozen embryo transfer (FET).We grouped patients who underwent FET between August 2021 and March 2022 based their vaccination status, number doses, interval last dose FET, then compared differences in pregnancy outcomes among...
In vitro maturation (IVM), a promising assisted reproductive technology (ART), has been evolving in clinical trials and applications. There is huge potential demand for IVM practice because it reduces the stimulation of gonadotropins to patients provides evidence safety neonatal birth. Unfortunately, rate oocytes vivo not as high due different microenvironment. Moreover, there are still controversies predicting developmental capability IVM. The granulosa cells (GCs) cumulus (CCs), closely...
Unilateral twin ectopic pregnancy is extremely rare in natural pregnancy, with an incidence rate of only 1 200,000-2,500,000, represents a major health risk for reproductive-aged women, leading to even life-threatening complications. There lack data on the prevalence this disease after in-vitro fertilization-embryo transfer (IVF-ET) cycles.We present case 51-year-old woman unilateral frozen embryo treated bilateral salpingectomy, followed by review literature.Twin very type that requires...
Worldwide, frozen embryo transfer (FET) has become a new strategy for the treatment of infertility. The success FET is closely related to endometrial receptivity. Does uterine artery Doppler during implantation window predict pregnancy outcome from first FET?A total 115 retrospectively collected cycles were included in study, with 64 clinical and 51 nonclinical pregnancy; There 99 nonabsent end-diastolic flow (NAEDF) 16 absent (AEDF) cycles. differences findings between different outcomes...
Background: This study evaluated the expression of cellular FLICE-like inhibitory protein (cFLIP) in granulosa cells (GCs) obtained from vitro fertilization-embryo transfer patients with advanced endometriosis. Methods: A total 267 endometriosis were enrolled this study. They divided into clinical pregnancy group (n = 114) and nonpregnancy 153). The expressions cFLIP mRNA level measured by real-time polymerase chain reaction (RT-PCR) Western blotting. related factors on analyzed using...
Background: Leiomyomatosis peritonealis disseminate (LPD) is a rare benign entity, but its histological origin remains unclear. Cases: An unusual DPL case which was diagnosed at 4 years after her initial laparoscopic uterine myomectomy with power morcellation, and recurred later. The findings during the exploratory laparotomy mimicked peritoneal carcinomatosis, characteristic of innumerous nodules throughout surface ranging from several millimeters to cenitimeters in diameters. She treated...
Objective To explore the relationship of expressions embryonic stem cell factor Nanog, Oct4, Sox2 in granulosa cells with polycystic ovary syndrome (PCOS). Methods Totally 40 PCOS patients and infertile cases due to tubal factors and/or male infertility who underwent vitro fertilization/intracytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET) at same period were recruited as experimental group control group, respectivly. Real-time PCR was used detect expression levels...