Elise M. Didion
A5012418128- Subterranean biodiversity and taxonomy
- Freshwater macroinvertebrate diversity and ecology
- Environmental DNA in Biodiversity Studies
- Insect symbiosis and bacterial influences
- Insect Resistance and Genetics
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Physiological and biochemical adaptations
- COVID-19 epidemiological studies
- Invertebrate Immune Response Mechanisms
- Mosquito-borne diseases and control
- Entomopathogenic Microorganisms in Pest Control
- Insect and Arachnid Ecology and Behavior
- Insect Utilization and Effects
- Hemiptera Insect Studies
- Insects and Parasite Interactions
- Insect-Plant Interactions and Control
- Influenza Virus Research Studies
- Viral Infections and Vectors
- Reproductive System and Pregnancy
- Cytomegalovirus and herpesvirus research
- Infection Control and Ventilation
- Neurobiology and Insect Physiology Research
- Reproductive Biology and Fertility
- Vaccine Coverage and Hesitancy
Case Western Reserve University
2023-2024
University School
2023-2024
Geriatric Research Education and Clinical Center
2023
Louis Stokes Cleveland VA Medical Center
2023
VA Northeast Ohio Healthcare System
2023
University of Cincinnati
2017-2021
University of Cincinnati Medical Center
2018
The Colorado potato beetle is one of the most challenging agricultural pests to manage. It has shown a spectacular ability adapt variety solanaceaeous plants and variable climates during its global invasion, and, notably, rapidly evolve insecticide resistance. To examine evidence rapid evolutionary change, understand genetic basis herbivory resistance, we tested for structural functional genomic changes relative other arthropod species using genome sequencing, transcriptomics, community...
Abstract Background The Hemiptera (aphids, cicadas, and true bugs) are a key insect order, with high diversity for feeding ecology excellent experimental tractability molecular genetics. Building upon recent sequencing of hemipteran pests such as phloem-feeding aphids blood-feeding bed bugs, we present the genome sequence comparative analyses centered on milkweed bug Oncopeltus fasciatus , seed feeder family Lygaeidae. Results 926-Mb is well represented by current assembly official gene set....
Abstract Current insights into the mosquito dehydration response rely on studies that examine specific responses but ultimately fail to provide an encompassing view of biology. Here, we examined underlying changes in biology mosquitoes associated with dehydration. Specifically, show increases blood feeding northern house mosquito, Culex pipiens , which was result both higher activity and a greater tendency land host. Similar observations were noted for Aedes aegypti Anopheles quadrimaculatus...
Introduction of monovalent COVID-19 mRNA vaccines in late 2020 helped to mitigate disproportionate COVID-19-related morbidity and mortality U.S. nursing homes (1); however, reduced effectiveness during the period Omicron variant predominance led recommendations for booster doses with bivalent that include an BA.4/BA.5 spike protein component broaden immune response improve vaccine against circulating variants (2). Recent studies suggest provide substantial additional protection SARS-CoV-2...
Having conquered water surfaces worldwide, the semi-aquatic bugs occupy ponds, streams, lakes, mangroves, and even open oceans. The diversity of this group has inspired a range scientific studies from ecology evolution to developmental genetics hydrodynamics fluid locomotion. However, lack representative strider genome hinders our ability more thoroughly investigate molecular mechanisms underlying processes adaptation diversification within group. Here we report sequencing manual annotation...
We examined whether the second monovalent SARS-CoV-2 mRNA booster increased antibody levels and their neutralizing activity to Omicron variants in nursing home residents (NH) healthcare workers (HCW). sampled 376 NH 63 HCW after primary vaccination, first boosters, for response pseudovirus neutralization assay against wild-type (WT) (Wuhan-Hu-1) strain, BA.1 BA.5 variants. Antibody progressively with each but subsequently waned over 3–6 months. residents, both those without prior infection,...
Abstract The Antarctic midge, Belgica antarctica , is a wingless, non-biting midge endemic to Antarctica. Larval development requires at least 2 years, but adults live only weeks. nonfeeding mate in swarms and females die shortly after oviposition. Eggs are suspended gel of unknown composition that expressed from the female accessory gland. This project characterizes molecular mechanisms underlying reproduction this by examining differential gene expression whole males, females, larvae, as...
Abstract Background The Hemiptera (aphids, cicadas, and true bugs) are a key insect order, with high diversity for feeding ecology excellent experimental tractability molecular genetics. Building upon recent sequencing of hemipteran pests such as phloem-feeding aphids blood-feeding bed bugs, we present the genome sequence comparative analyses centered on milkweed bug Oncopeltus fasciatus , seed feeder family Lygaeidae. Results 926-Mb is well represented by current assembly official gene set....
To date, SARS-CoV-2 has infected more than 1.6 million U.S. nursing home (NH) residents and killed 160,000.1 Vaccination plays a vital role in preventing infection reducing morbidity mortality burden this population. A single bivalent COVID-19 mRNA vaccine broadens immunity reduces infection, hospitalization, death beyond that from monovalent vaccination.2, 3 We extend our work here by evaluating the immune response following second dose. The current analysis extends longitudinal data serial...
Vaccines and vaccine boosting have blunted excess morbidity mortality from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in older nursing home residents (NHR). However, the impact of repeated vaccination on T-cell response based biological sex prior NHR remain understudied.
Tsetse flies are important vectors of human and animal trypanosomiasis. Ability to reduce tsetse populations is an effective means disease control. Lactation essential component tsetse's viviparous reproductive physiology requires a dramatic increase in the expression synthesis milk proteins by gland organ order nurture larval growth. In between each gonotrophic cycle, ceases production tubules undergo nearly two-fold reduction width (involution). this study, we examined role autophagy plays...
Abstract The Colorado potato beetle is one of the most challenging agricultural pests to manage. It has shown a spectacular ability adapt variety solanaceaeous plants and variable climates during its global invasion, and, notably, rapidly evolve insecticide resistance. To examine evidence rapid evolutionary change, understand genetic basis herbivory resistance, we tested for structural functional genomic changes relative other arthropod species using genome sequencing, transcriptomics,...
Abstract The semi-aquatic bugs conquered water surfaces worldwide and occupy ponds, streams, lakes, mangroves, even open oceans. As such, they inspired a range of scientific studies from ecology evolution to developmental genetics hydrodynamics fluid locomotion. However, the lack representative strider genome hinders thorough investigations mechanisms underlying processes adaptation diversification in this group. Here we report sequencing manual annotation Gerris buenoi (G. buenoi) genome,...
Abstract Diapause is a hormonally driven response which triggered by environmental cues that signal impending adverse conditions and prompts metabolic, developmental, behavioral changes to allow survival until the return of favorable conditions. Microbial symbionts have been shown influence metabolism, development, behavior their host organisms, all are common diapause-associated characteristics. Surveys bacterial components in relation diapause examined few systems, species usually inactive...
We examined whether the second monovalent SARS-CoV-2 mRNA booster increased antibody levels and their neutralizing activity to Omicron variants in nursing home residents (NH) healthcare workers (HCW). sampled 367 NH 60 HCW after primary vaccination, first boosters, for response pseudovirus neutralization assay against wild-type (WT) (Wuhan-Hu-1) strain BA1 variant. Antibody progressively with each but subsequently waned over weeks. residents, both those without prior infection, had a robust...
Abstract Background The CDC recommends the more immunogenic adjuvanted and high-dose flu vaccines over standard-dose, non-adjuvanted for individuals above 65 years old. current study compares trivalent inactivated vaccine (aTIV, FLUAD) versus (HD-IIV3, FLUZONE HD) to determine if they met non-inferiority standards older long-term care facility (LTCF) residents. Methods We collected blood from residents participating in a randomized 1:1 active control trial comparing MF59C.1 vaccine, aTIV...
Abstract The Antarctic midge, Belgica antarctica , is a wingless, non-biting midge endemic to Antarctica. Larval development requires at least two years, but adult life lasts only weeks. nonfeeding adults mate in swarms and females die shortly after oviposition. Eggs are suspended gel of unknown composition that expressed from the female accessory gland. This project characterizes molecular mechanisms underlying reproduction this by examining differential gene expression whole males,...