A5100725118- Viral-associated cancers and disorders
- Acute Kidney Injury Research
- Effects and risks of endocrine disrupting chemicals
- Sperm and Testicular Function
- Diabetes Treatment and Management
- Legume Nitrogen Fixing Symbiosis
- Soybean genetics and cultivation
- Hepatitis Viruses Studies and Epidemiology
- GABA and Rice Research
- Immunotoxicology and immune responses
- Brucella: diagnosis, epidemiology, treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Fungal Infections and Studies
- Hepatitis C virus research
- Birth, Development, and Health
- Toxic Organic Pollutants Impact
- Autoimmune and Inflammatory Disorders Research
- Asthma and respiratory diseases
- Antifungal resistance and susceptibility
- Infant Nutrition and Health
- Lymphoma Diagnosis and Treatment
- Folate and B Vitamins Research
- Heavy Metal Exposure and Toxicity
- Cardiac Health and Mental Health
- Antiplatelet Therapy and Cardiovascular Diseases
Beijing YouAn Hospital
2025
Capital Medical University
2020-2025
Wuhan University of Science and Technology
2016-2024
Ningbo Academy of Agricultural Sciences
2024
Nanjing Medical University
2024
Jilin Academy of Agricultural Sciences
2021
Sichuan Agricultural University
2019-2020
Beijing Ditan Hospital
2020
Chongqing Medical University
2020
Roche (China)
2020
Abstract Cadmium is one of the environmental and occupational pollutants its potential adverse effects on human health have given rise to substantial concern. causes damage male reproductive system via induction germ-cell apoptosis; however, underlying mechanism cadmium-induced toxicity in Leydig cells remains unclear. In this study, twenty mice were divided randomly into four groups exposed CdCl 2 at concentrations 0, 0.5, 1.0 2.0 mg/kg/day for consecutive weeks. Testicular injury, abnormal...
Invasive pulmonary aspergillosis (IPA) is a common opportunistic infection in patients with severe liver disease (SLD), which increases the mortality of patients. The aim this study was to evaluate efficacy and safety voriconazole for IPA SLD explore an optimal antifungal regimen. This retrospective cohort diagnosed proven or probable at Beijing Youan Hospital, Capital Medical University between January 1, 2012 31, 2023. Univariate multivariate logistic regression analysis were performed...
Despite advancements in antiretroviral therapy, AIDS-related diffuse large B-cell lymphoma (AR-DLBCL) remains a major cause of morbidity and mortality. Compared to non-HIV-infected individuals, AR-DLBCL presents with considerable disease heterogeneity, which impairs the accuracy current prognostic tools. This study aims develop novel model enhance risk assessment for AR-DLBCL. We retrospectively analyzed 90 cases using univariate multivariate analyses identify clinical factors affecting...
Di(2-ethylhexyl) phthalate (DEHP), a plasticizer of synthetic polymers, is well-known endocrine disrupting chemical (EDC) and reproductive toxicant. Addressing the unclear mechanism DEHP-induced dysfunction, this study used GC-2spd cells to investigate molecular involved in toxicity male system. The results indicated that apoptotic cell death was significantly induced by DEHP exposure over 100 μM. Furthermore, treatment could induce oxidative stress involving decrease superoxide dismutase...
Abstract As the highly risk and infectious diseases, outbreak of coronavirus disease 2019 (COVID-19) poses unprecedent challenges to global health. Up March 3, 2020, SARS-CoV-2 has infected more than 89,000 people in China other 66 countries across six continents. In this study, we used 10 new sequenced genomes combined 136 from GISAID database investigate genetic variation population demography through different analysis approaches (e.g. Network, EBSP, Mismatch, neutrality tests). The...
Many studies have demonstrated the efficacy of folic acid (FA) supplementation in prevention neural tube defects (NTDs), although extent NTDs varies among individuals different races and ethnic origin. China is a multi-ethnic country with no standard practice for FA-fortified food. Milk consumed by women, but little known about effects milk on folate concentration maternal blood neonatal umbilical cord Han Mongolian women after stopping taking supplement month five month, respectively. The...
The objective of this study was to elucidate the burden, risk factors, and prognosis serious non-AIDS-defining events among admitted cART-naive AIDS patients in China. evaluation factors NADEs carried out 1309 (median age: 38.2 years, range: 18–78 years) Beijing Ditan Hospital between January 2009 December 2018. Among patients, 143 (10.9%) had at least one NADEs, including 49 (3.8%) with cerebrovascular diseases, 37 (2.8%) cancers, 28 (2.1%) chronic kidney 26 (2.0%) cardiovascular 18 (1.4%)...
Rheumatoid arthritis (RA) significantly impacts the health of Chinese patients. Conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) are used as standard treatment for patients with RA. However, RA have reported poor compliance csDMARDs. This study aims to better understand safety and using csDMARDs in treatment. Face-to-face interviews were conducted by questionnaires on 400 100 rheumatologists from 13 cities China. Rheumatologists Tier 3 Class A hospitals independent...
Riemerella anatipestifer is a gram-negative bacterium that mainly infects ducks, turkeys and other birds. In previous study, we established markerless mutation system based on the pheS mutant as counterselectable marker. However, toxic effect of p-Cl-Phe R. strain expressing was weak blood agar plates. this successfully obtained streptomycin-resistant derivative ATCC11845 using 100 μg/mL streptomycin selection pressure. Then, demonstrate rpsL can be used marker in strain, namely, ATCCs. A...
Previous studies have reported the association between particulate matter (PM) and childhood allergic rhinitis (AR). However, it is unclear whether food allergy (FA) modifies PM–AR association. We aimed at evaluating effect of modification FA on in preschool children. adopted a cross-sectional study conducted questionnaire survey among children aged 3–6 years 7 cities China from June 2019 to 2020 collect information AR FA. used combination multilevel logistic regression restricted cubic...
Percutaneous coronary intervention (PCI) is an effective method for the treatment of heart disease. Cardiac rehabilitation and continuous nursing management after discharge are key to ensure quality life patients. This study aimed explore significance WeChat platform in care PCI. We collected clinical data 90 PCI patients 2 centers from January 2020 July 2023, divided into groups: group based on control group. Continuous was implemented immediately discharge. After 1-year follow-up, we...
Objective To study the changes of glucagon–like peptide–1(GLP–1) and effects GLP–1 analogues on sleep – disordered breathing in type 2 diabetic patients with obstructive apnea hypopnea syndrome(OSAHS). Methods One hundred sixty–nine were enrolled as research subjects from in–patients normal control October 2012 to September 2014. Based oral glucose tolerance test (OGTT) polysomnography (PSG), divided into OSAHS–T2DM group (45), OSAHS (42), T2DM (47) (40). Fasting postprandial GLP 1 3...
Objective To analyze the epidemic characteristics and dynamic changes of brucellosis in Tangshan, explore influencing factors different periods, so as to provide a scientific basis for its prevention control. Methods A retrospective analysis method was used collect monitoring data Tangshan from 1950 2016 understand three dimension distributions periods. Results A total 2 438 cases were reported 2016, average incidence rate 0.48/105, no death reported. The peak 2015, with an...