A5100390610- Parkinson's Disease Mechanisms and Treatments
- Treatment of Major Depression
- Mental Health Research Topics
- Neurological disorders and treatments
- Reproductive Biology and Fertility
- Medical Research and Treatments
- Tryptophan and brain disorders
- Balance, Gait, and Falls Prevention
- Genetic Neurodegenerative Diseases
- Botulinum Toxin and Related Neurological Disorders
- Migraine and Headache Studies
- Epilepsy research and treatment
- Obsessive-Compulsive Spectrum Disorders
- Advanced MRI Techniques and Applications
- Sperm and Testicular Function
- Functional Brain Connectivity Studies
- Bipolar Disorder and Treatment
- Transcranial Magnetic Stimulation Studies
- Cerebral Palsy and Movement Disorders
- Healthcare professionals’ stress and burnout
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Cardiac Health and Mental Health
- Acupuncture Treatment Research Studies
- Advanced Neuroimaging Techniques and Applications
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Fudan University
2024
Beijing Luhe Hospital Affiliated to Capital Medical University
2023-2024
Capital Medical University
2018-2023
National Clinical Research Center for Digestive Diseases
2021-2023
Guangdong Provincial Hospital of Traditional Chinese Medicine
2023
Jianghan University
2022-2023
Beijing Tian Tan Hospital
2018-2022
Guangdong Provincial People's Hospital
2021-2022
Guangdong Academy of Medical Sciences
2021-2022
Southern Medical University
2021-2022
Background Parkinson disease (PD) is a common movement disorder. Patients with PD have multiple gait impairments that result in an increased risk of falls and diminished quality life. Therefore, measurement important for the management PD. Objective We previously developed smartphone-based dual-task assessment was validated healthy adults. The aim this study to test validity people PD, examine association between app-derived metrics clinical functional characteristics Methods Fifty-two...
This study comparatively evaluates the characteristics of glutaraldehyde-treated acellular bovine and donkey pericardium using histological electronic microscopic observation techniques, shrinkage temperature, mechanical properties, as well determining calcium phosphorus content at 4 8 weeks after subcutaneous implantation in Wistar rats. Donkey was significantly thinner compared with (1.622 ± 0.161 mm vs. 4.027 0.401 mm, P < 0.0001) associated greater tensile strength (14.21 3.81 MPa 3.78...
Background: Impaired motor control is one of the most common symptoms multiple system atrophy (MSA). It arises from dysfunction cerebellum and its connected neural networks, including primary cortex (M1), associated with altered spontaneous (i.e., resting-state) brain network activity. Non-invasive repetitive transcranial magnetic stimulation (rTMS) selectively facilitates excitability supraspinal networks. Repeated rTMS sessions have been shown to induce long-term changes both resting-state...
Background: Major depressive disorder is characterized by the presence of at least five nine specific symptoms that contribute to clinically significant functional impairment. This analysis examined effect desvenlafaxine (50 or 100 mg) versus placebo on symptom cluster scores and association between early improvement in clusters symptomatic remission week 8. Methods: Using data from double-blind, placebo-controlled studies for treatment major ( N=4317), 50 mg based 17-item Hamilton Rating...
While multiple system atrophy (MSA) presents with high heterogeneous motor and nonmotor symptoms, the associations between clinical phenotypes prognosis are unclear.
Aim This study examined the effects of group psychological counselling on transition shock in newly graduated nurses. Background Newly nurses are often faced with as they enter workforce. Helping them adapt to new work environment and role quickly possible is an important goal for nursing managers. Method prospective, parallel-group, quasi-experimental trial enrolled 71 who were randomly assigned intervention (n = 38) or control 41) group. In addition routine hospital training, received...
Abstract Background Major depressive disorder (MDD) with atypical features, namely depression features (AFD), is one of the most common clinical specifiers MDD, closely associated bipolar (BD). However, there still a lack guidelines for diagnosis, treatment, and prognosis AFD. Our study mainly focuses on three issues about how to identify AFD, what appropriate individualized treatment are predictive biomarkers conversion BD. Methods The Study Individualized Diagnosis Treatment Depression...
Objective: This study aimed to evaluate the psychometric properties of Chinese version Clinically Useful Depression Outcome Scale (CUDOS). Methods: One hundred ninety patients with major depressive disorder (MDD) according Diagnostic and Statistical Manual Mental Disorders, Fifth Edition (DSM-5) criteria were recruited study. The English CUDOS was translated into using a forward backward translation method, which guidelines adaptation validation instruments in cross-cultural health care...
Background and objectives The Movement Disorder Society’s Unified Parkinson’s Disease Rating Scale Part III (MDS-UPDRS III) is mostly common used for assessing the motor symptoms of disease (PD). In remote circumstances, vision-based techniques have many strengths over wearable sensors. However, rigidity (item 3.3) postural stability 3.12) in MDS-UPDRS cannot be assessed remotely since participants need to touched by a trained examiner during testing. We developed four scoring models neck,...
Lacunae are imaging biomarkers of cerebral small vessel disease (CSVD) and correlated with the degree gait instability in Parkinson's (PD). The wearing-off phenomenon (WO) occurs more frequently PD patients as progresses. present study aimed to investigate overall impact quantity location lacunae on WO PD.This retrospective, single-center included 315 consecutive eligible from Beijing Tiantan Hospital May 2016 August 2018. We collected data demographics clinical features, assessed examined...
This article has been retracted. A retraction notice can be found at https://doi.org/10.3233/JIFS-219321.
Abstract Purpose/Background Heterogeneity has been documented in trajectories of symptom change during antidepressant treatment for major depressive disorder (MDD). It is unclear whether distinct exist functioning treatment. Methods/Procedures This analysis explored MDD and tested they corresponded to change. Data were from 4317 patients pooled 9 randomized placebo-controlled trials. Growth mixture modeling was used identify Hamilton Rating Scale Depression (HRSD) Sheehan Disability (SDS)...
The Hospital Anxiety and Depression Scale (HADS) is a widely used screening tool for depression anxiety in patients with medical illnesses. This study aimed to explore the psychometric properties of HADS major using item response theory method. A total 460 completed HADS. Rasch analyses were examine unidimensionality, fit, local dependency, reliability, ordering categories, differential functioning (DIF) targeting. showed two-dimensional construct. All items fit model. Three pairs minor but...