Juan Jesús Ruiz

ORCID: 0000-0002-5316-2092
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About
Contact & Profiles
Research Areas
  • Substance Abuse Treatment and Outcomes
  • Neurotransmitter Receptor Influence on Behavior
  • Alcohol Consumption and Health Effects
  • Tryptophan and brain disorders
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Opioid Use Disorder Treatment
  • Hepatitis C virus research
  • HIV, Drug Use, Sexual Risk
  • Stress Responses and Cortisol
  • Cannabis and Cannabinoid Research
  • Forensic Toxicology and Drug Analysis
  • Sphingolipid Metabolism and Signaling
  • Schizophrenia research and treatment
  • Advanced Image and Video Retrieval Techniques
  • Eicosanoids and Hypertension Pharmacology
  • Public Health and Social Inequalities
  • Psychedelics and Drug Studies
  • Diet, Metabolism, and Disease
  • Viral Infections and Immunology Research
  • Robotics and Sensor-Based Localization
  • Gambling Behavior and Treatments
  • Neuroscience of respiration and sleep
  • Virtual Reality Applications and Impacts
  • Alzheimer's disease research and treatments
  • Mental Health Research Topics

Centro Universitario de Tecnología y Arte Digital
2023

Universidad Pablo de Olavide
2018

Hospital del Mar Research Institute
2017

Universitat Autònoma de Barcelona
2017

Ayuntamiento de Sevilla
2013-2014

Universidad de Málaga
2012

The treatment for cocaine use constitutes a clinical challenge because of the lack appropriate therapies and high rate relapse. Recent evidence indicates that immune system might be involved in pathogenesis addiction its co-morbid psychiatric disorders. This work examined plasma pro-inflammatory cytokine chemokine profile abstinent users (n = 82) who sought outpatient age/sex/body mass-matched controls 65). Participants were assessed with diagnostic interview Psychiatric Research Interview...

10.1111/adb.12156 article EN Addiction Biology 2014-05-22

Substance use disorder (SUD) is a major global public health challenge, frequently co-occurring with psychiatric conditions such as attention-deficit/hyperactivity (ADHD). Endocannabinoid system (ECS) dysregulation has been implicated in both SUD and ADHD, but the interplay between these remains poorly understood. This study investigates plasma concentrations of endocannabinoid-congeners individuals SUD, without comorbid to identify potential biomarkers. exploratory included 469 participants...

10.1016/j.pnpbp.2025.111350 article EN cc-by Progress in Neuro-Psychopharmacology and Biological Psychiatry 2025-04-01

Cocaine is associated with serious health problems including psychiatric co-morbidity. There a need for the identification of biomarkers stratification cocaine-addicted subjects. Several studies have evaluated circulating endocannabinoid-related lipids as inflammatory, metabolic and mental disorders. However, little known in substance use This study characterizes both free N-acyl-ethanolamines (NAEs) 2-acyl-glycerols abstinent cocaine addicts from outpatient treatment programs who were...

10.1111/adb.12107 article EN Addiction Biology 2013-11-01

La adicción a cocaína es un problema de salud creciente y entre sus complicaciones destaca la elevada prevalencia comorbilidad psicopatológica. detección temprana los trastornos psicopatológicos asociados al consumo necesaria para optimizar asistencia sanitaria mejorar el pronóstico. El objetivo principal este estudio estimar características psicopatológica en una población sujetos que solicitan atención por uso tratamiento ambulatorio. Se reclutaron 110 consumidores vía nasal evaluados con...

10.20882/adicciones.124 article ES Adicciones 2014-03-01

Despite alcohol being the most often used addictive substance among addicted patients, use of other substances such as cocaine has increased over recent years, and combination both drugs aggravates health impairment complicates clinical assessment. The aim present study is to identify characterize heterogeneous subgroups cocaine- alcohol-addicted patients with common characteristics based on disorders, psychiatric comorbidity impulsivity. A total 214 subjects and/or disorders were recruited...

10.3389/fpsyt.2018.00026 article EN cc-by Frontiers in Psychiatry 2018-02-12

Recent studies have identified biomarkers related to the severity and pathogenesis of cocaine addiction common comorbid psychiatric disorders. Monitoring these plasma mediators may improve stratification users seeking treatment. Because neurotrophic factors are involved in neural plasticity, neurogenesis neuronal survival, we determined concentrations brain-derived factor (BDNF), insulin-like growth 1 (IGF-1) IGF-1 binding protein 3 (IGFBP-3) a cross-sectional study with abstinent who sought...

10.1371/journal.pone.0118610 article EN cc-by PLoS ONE 2015-03-03

Background Cocaine use disorder (CUD) is a complex health condition, especially when it accompanied by comorbid psychiatric disorders (dual diagnosis). Dual diagnosis associated with difficulties in the stratification and treatment of patients. One major challenges clinical practice addiction psychiatry lack objective biological markers that indicate degree consumption, severity addiction, level toxicity response to patients CUD. These potential biomarkers would be fundamental players...

10.7717/peerj.3926 article EN cc-by PeerJ 2017-10-12

Major depressive disorder (MDD) is the most prevalent comorbid mental among people with substance use disorders. The MDD can be both primary and substance-induced its accurate diagnosis represents a challenge for clinical practice treatment response. Recent studies reported alterations in circulating expression of inflammatory mediators patients psychiatric disorders, including those related to use. aim study was explore TNF-α, IL-1β, CXCL12, CCL2, CCL11 (eotaxin-1) CX3CL1 (fractalkine) as...

10.1371/journal.pone.0213791 article EN cc-by PLoS ONE 2019-03-14

Abstract Cognitive reserve (CR) is the capability of an individual to cope with a brain pathology through compensatory mechanisms developed cognitive stimulation by mental and physical activity. Recently, it has been suggested that CR protective role against initiation substance use, consumption patterns decline can improve responses treatment. However, never linked function neurotrophic factors in context alcohol consumption. The present cross-sectional study aims evaluate association...

10.1038/s41598-021-95131-2 article EN cc-by Scientific Reports 2021-08-02

(1) Background: Alcohol Use Disorder (AUD) is associated with functional disruption of several brain structures that may trigger cognitive dysfunction. One the mechanisms alcohol-associated impairment has been proposed to arise from its direct impact on immune system, which culminates in release cytokines and chemokines can eventually reach brain. also disrupt blood-brain barrier, facilitating penetration pro-inflammatory molecules throughout vascular endothelial growth factor A (VEGFA)....

10.3390/biomedicines10050947 article EN cc-by Biomedicines 2022-04-20

During the last years, UAVs have proved to be an essential tool in mapping industry. Furthermore, next generation of is envisioned work cooperatively, following swarming/teaming concept. This letter presents MGRAPH, a novel approach generate incremental mosaic real time from UAV swarm. The algorithm based on and fusion multiples submosaics represented by homography graphs. Implementation takes advantage parallel processing metadata georeferenced over geographic information system. A...

10.1109/lra.2018.2844304 article EN IEEE Robotics and Automation Letters 2018-01-01

Abstract The lack of effective treatments and a high rate relapse in cocaine addiction constitute major health problem. present study was conducted to examine the expression tryptophan-derived metabolites context psychiatric comorbidity, which is common addicted subjects. Abstinent patients with use disorder (CUD) control subjects were recruited for cross-sectional study. Participants assessed semi-structured diagnostic interview (PRISM) based on DSM-IV-TR substance mental disorders. Plasma...

10.1038/s41598-019-53312-0 article EN cc-by Scientific Reports 2019-11-14

Cocaine continues to be a worldwide public health concern in Europe. To improve prognosis and intervention, it is necessary understand the characteristics of patients who depend on services where they receive care. The objective analyze differences among use cocaine between ambulatory residential resources better adapt treatment. This descriptive, observational study two populations users treatment: therapeutic community (ATC) (TC). PRISM diagnostic interview was used for both groups. An...

10.1080/02791072.2017.1342151 article EN Journal of Psychoactive Drugs 2017-07-06

Abstract Gender significantly influences sociodemographic, medical, psychiatric and addiction variables in cocaine outpatients. Educational level may be a protective factor showing less severe addictive disorders, longer abstinence periods, better cognitive performance. The aim was to estimate gender-based differences the influence of educational on clinical associated with use disorder (CUD). A total 300 cocaine-consuming patients undergoing treatments were recruited assessed using...

10.1038/s41598-021-00472-7 article EN cc-by Scientific Reports 2021-10-22

For a long time, Substance Use Disorders (SUDs) were not considered component in the etiology of dementia. The fifth edition Diagnostic and Statistical Manual Mental introduced substance-induced neurocognitive disorders, incorporating this notion to clinical practice. However, detection monitoring neurodegenerative processes SUD patients remain major challenge, especially when early diagnosis is required. In present study, we aimed investigate new potential biomarkers neurodegeneration that...

10.3390/ijms24021183 article EN International Journal of Molecular Sciences 2023-01-07

Prolonged stays in the intensive care unit (ICU) cause difficulties rehabilitation and other disorders for patients. This problem is exacerbated case of pediatric The use virtual reality can help with lack external stimuli contribute as potential nonpharmacological therapies some patient processes. To this end, we have developed a application ICU tool treatment delirium. consists two applications: an immersive environment headset used by patient, web managed therapist which they customize,...

10.1109/mcg.2023.3239676 article EN IEEE Computer Graphics and Applications 2023-03-01

Abstract Background Methadone and buprenorphine are the most prevalent types of opioid maintenance programs in Andalusia. The main objective is comparing functional status patients with pharmacological treatments according to different socio-demographic characteristic, health disabilities domains sexual difficulties. Methods A total 593 from Andalusia community, 329 were undergoing methadone treatment 264 treatment. interviewed by opioid-related variables, assessed functioning, disability (...

10.1186/s12954-021-00488-2 article EN cc-by Harm Reduction Journal 2021-04-13
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