- Advanced Radiotherapy Techniques
- Advances in Oncology and Radiotherapy
- Medical Imaging Techniques and Applications
- Prostate Cancer Diagnosis and Treatment
- Management of metastatic bone disease
- Radiation Therapy and Dosimetry
- Radiation Dose and Imaging
- Advanced MRI Techniques and Applications
- Lung Cancer Diagnosis and Treatment
- Advanced X-ray and CT Imaging
- Brain Metastases and Treatment
- Radiology practices and education
- Glioma Diagnosis and Treatment
- Sarcoma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Meningioma and schwannoma management
- MRI in cancer diagnosis
- Traumatic Brain Injury and Neurovascular Disturbances
- Cancer survivorship and care
- Traumatic Brain Injury Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Patient-Provider Communication in Healthcare
- Pancreatic and Hepatic Oncology Research
- Childhood Cancer Survivors' Quality of Life
- Palliative Care and End-of-Life Issues
Princess Margaret Cancer Centre
2016-2025
University of Toronto
2015-2025
University Health Network
2016-2025
Real-Time Innovations (United States)
2023
Harvard University
2021
University College Hospital, Ibadan
2021
University of Ibadan
2021
Brigham and Women's Hospital
2021
Universidad del Noreste
2021
Northeastern University
2021
This commentary discusses the implementation of online adaptive radiation therapy (oART) in cancer treatment within context current challenges faced by professionals. oART enables modifications to plans based on daily imaging, enhancing target accuracy while minimising harm surrounding organs. Despite its potential improve patient outcomes, application is hindered notable barriers, particularly human resources. A global shortage skilled professionals such as therapists or therapeutic...
To describe a comprehensive workflow for MRI-guided online adaptive stereotactic body radiation therapy (SBRT) specific to upper gastrointestinal cancer patients with abdominal compression on 1.5T MR-Linac system. Additionally, we discuss the workflow's clinical feasibility and early experience in case of 16 liver pancreas patients.Eleven five were treated MRI-guidance under compression. Two received single-fraction treatments; remainder plus all fractions. A total 65 treatment sessions...
The present study used cone beam computed tomography (CBCT) to measure the inter- and intrafraction uncertainties for intracranial stereotactic radiosurgery (SRS) using Leksell Gamma Knife (GK).Using a novel CBCT system adapted GK treatment unit, images were acquired immediately before after each session within context of research ethics board-approved prospective clinical trial. Patients immobilized in coordinate frame (LCF) both volumetric imaging GK-SRS delivery. relative displacement...
To develop a practice-based training strategy to transition from radiation oncologist therapist-driven prostate MR-Linac adaptive radiotherapy.In phase 1, 7 therapists independently contoured the and organs-at-risk on T2-weighted MR images 11 previously treated patients. Contours were evaluated quantitatively (i.e. Dice similarity coefficient [DSC] calculated against generated online contours) qualitatively using 5-point Likert scale; score ≥ 4 was deemed pass, 90% pass rate required proceed...
OBJECTIVES : A non-invasive immobilization system consisting of a thermoplastic mask with image-guidance using cone-beam CT (CBCT) and infrared (IR) tracking has been developed to ensure minimal inter- intra-fractional movement during Gamma Knife radiosurgery. Prior clinical use for patients on Knife, this study clinically evaluates the accuracy stability novel in treated standard fractionated radiation therapy linear accelerator.This prospective cohort evaluated adult planned brain...
PurposeSubstantial, unanticipated anatomic variances during cone-beam CT (CBCT)-guided radiotherapy can potentially impact treatment accuracy and clinical outcomes. This study assessed patterns of practice CBCT reported by RTTs subsequent interventions for multiple-disease sites.MethodsA chart review was conducted at a large cancer centre patients treated with daily online CBCT-guided radiotherapy. Patients selected were identified via RTT-reported that then triggered offline...
Integrated magnetic resonance linear accelerator (MR-Linac) systems offer potential for biologically based adaptive radiation therapy using apparent diffusion coefficient (ADC). Accurate tracking of longitudinal ADC changes is key to establishing ADC-driven dose adaptation. Here, we report repeatability and reproducibility intraprostatic deformable image registration (DIR) correct inter-fraction prostate changes.
Obstructive sleep apnea (OSA) is a prevalent and debilitating condition that significantly underdiagnosed. The majority of adults with someone-a partner. Partners can play significant role in the patient's OSA diagnosis. goal this work to describe facilitators barriers diagnosis as discussed by patients their partners.This was qualitative secondary analysis results drawn from 20 dyadic interviews, conducted 1 couple at time, newly diagnosed adult partners. Qualitative interview data were...
The purpose of this study was to characterize automatic remote couch adjustment and assess the accuracy corrections following localization with cone-beam CT (CBCT). Automatic movement evaluated through passive reflector markers placed on a phantom, tracked an optical tracking system (OTS). Repeated movements in lateral, cranial/caudal, vertical directions were monitored OTS velocity response time. In conjunction CBCT, table for patient displacements initial setup available four linear...