- Colorectal and Anal Carcinomas
- Advanced Radiotherapy Techniques
- Colorectal Cancer Surgical Treatments
- Medical Imaging Techniques and Applications
- Salivary Gland Tumors Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Gastric Cancer Management and Outcomes
- Hepatocellular Carcinoma Treatment and Prognosis
- Ear and Head Tumors
- Thyroid Cancer Diagnosis and Treatment
- Head and Neck Cancer Studies
- Lung Cancer Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Surgical site infection prevention
- MRI in cancer diagnosis
- Colorectal Cancer Treatments and Studies
- Cancer Genomics and Diagnostics
- Head and Neck Anomalies
- Cervical Cancer and HPV Research
- Management of metastatic bone disease
- Thyroid and Parathyroid Surgery
- Radiomics and Machine Learning in Medical Imaging
- Cancer survivorship and care
- Advanced Neuroimaging Techniques and Applications
- Hearing, Cochlea, Tinnitus, Genetics
Princess Margaret Cancer Centre
2018-2024
University of Toronto
2011-2024
University Health Network
2018-2024
Université de Montréal
2020
Western University
2013-2018
London Health Sciences Centre
2018
Cancer Care Ontario
2013-2014
To describe a comprehensive workflow for MRI-guided online adaptive stereotactic body radiation therapy (SBRT) specific to upper gastrointestinal cancer patients with abdominal compression on 1.5T MR-Linac system. Additionally, we discuss the workflow's clinical feasibility and early experience in case of 16 liver pancreas patients.Eleven five were treated MRI-guidance under compression. Two received single-fraction treatments; remainder plus all fractions. A total 65 treatment sessions...
The globally dominant treatment with curative intent for locally advanced esophageal squamous cell carcinoma (ESCC) is neoadjuvant chemoradiotherapy (nCRT) subsequent esophagectomy. This multimodal leads to around 60% overall 5-year survival, yet impaired post-surgical quality of life. Observational studies indicate that curatively intended chemoradiotherapy, so-called definitive (dCRT) followed by surveillance the primary tumor site and regional lymph node stations surgery only when needed...
The main objective of this study was to review the clinicopathologic characteristics and outcome patients with oncocytic papillary thyroid carcinoma (PTC) poorly differentiated (PDTC). secondary evaluate prevalence outcomes RAI use in population.Patients PTC PDTC who were treated at a quaternary cancer centre between 2002 2017 retrospectively identified from an institutional database. All had expert pathology ensure consistent reporting definition. cumulative incidence function used analyse...
Abstract Many multicenter randomized clinical trials in oncology are conducted through the National Clinical Trials Network (NCTN), an organization consisting of 5 cooperative groups. These groups made up multidisciplinary investigators who work collaboratively to conduct that test novel therapies and establish best practice for cancer care. Unfortunately, disparities trial leadership evident. To examine current state diversity, equity, inclusion across NCTN, independent NCTN Task Force...
Colorectal cancer was the third most common malignancy worldwide in 2018, and patients present with or develop distant metastases. liver metastases are commonly observed because of vascular drainage colon superior rectum. Current guidelines recommend surgical resection as first-line treatment; however, 80% to 90% colorectal ineligible for primary resection. For unresectable disease, a multidisciplinary treatment approach is favored, incorporating systemic therapy toolbox local ablative...
Background: The risk factors for acute care utilization in gynecologic oncology patients are poorly understood. This study aimed to evaluate the of our centre’s radiation nursing clinic (RNC) by receiving radiotherapy (RT). Methods: was a retrospective cohort gynecological cancer treated with RT at an academic centre between 1 August 2021 and 31 January 2022. Data on socio-demographics, clinical treatment characteristics, RNC visits were collected summarized descriptive statistics. Wilcoxon...
Dose painting of hypoxic tumour sub-volumes using positron-emission tomography (PET) has been shown to improve controlin silicoin several sites, predominantly head and neck lung cancers. Pancreatic cancer presents a more stringent challenge, given its proximity critical gastro-intestinal organs-at-risk (OARs), anatomic motion, impediments reliable PET hypoxia quantification. A radiobiological model was developed estimate clonogen survival fraction (SF), using18F-fluoroazomycin arabinoside...
2023 Background: Brain metastases (BM) in advanced thyroid cancer are rare; however, they may be underreported as staging brain imaging is not routine. Prognostic features and molecular alterations for this group poorly described. We characterized the clinical of with BM evaluated differences survival. Methods: In single-center retrospective analysis, patients metastatic radioactive iodine refractory well-differentiated, poorly-differentiated, or medullary carcinoma seen at Princess Margaret...