A5035901116- Head and Neck Cancer Studies
- Advanced Radiotherapy Techniques
- Lung Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- COVID-19 and healthcare impacts
- Dysphagia Assessment and Management
- Cancer Diagnosis and Treatment
- Radiation Dose and Imaging
- Prostate Cancer Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Economic and Financial Impacts of Cancer
- Medical Imaging Techniques and Applications
- Palliative Care and End-of-Life Issues
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Research Studies
- Advances in Oncology and Radiotherapy
- Healthcare cost, quality, practices
- Head and Neck Surgical Oncology
- Radiation Therapy and Dosimetry
- Salivary Gland Tumors Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- MRI in cancer diagnosis
- Effects of Radiation Exposure
- Venous Thromboembolism Diagnosis and Management
- Frailty in Older Adults
The Royal Wolverhampton NHS Trust
2021-2024
Raigmore Hospital
2024
University Hospitals of Derby and Burton NHS Foundation Trust
2024
Worcestershire Royal Hospital
2017-2022
Clatterbridge Cancer Centre NHS Foundation Trust
2019-2021
Worcestershire Acute Hospitals NHS Trust
2016-2021
University of Birmingham
2016
Worcestershire Health and Care NHS Trust
2016
Edwards (United Kingdom)
2015
Queen Elizabeth Hospital Birmingham
2015
Over half a million individuals are diagnosed with head and neck cancer each year globally. Radiotherapy is an important curative treatment for this disease, but it requires manual time to delineate radiosensitive organs at risk. This planning process can delay while also introducing interoperator variability, resulting in downstream radiation dose differences. Although auto-segmentation algorithms offer potentially time-saving solution, the challenges defining, quantifying, achieving expert...
Over half a million individuals are diagnosed with head and neck cancer each year worldwide. Radiotherapy is an important curative treatment for this disease, but it requires manual time consuming delineation of radio-sensitive organs at risk (OARs). This planning process can delay treatment, while also introducing inter-operator variability resulting downstream radiation dose differences. While auto-segmentation algorithms offer potentially time-saving solution, the challenges in defining,...
<h2>Summary</h2><h3>Background</h3> Most newly diagnosed oropharyngeal and hypopharyngeal cancers are treated with chemoradiotherapy curative intent but at the consequence of adverse effects on quality life. We aimed to investigate if dysphagia-optimised intensity-modulated radiotherapy (DO-IMRT) reduced radiation dose dysphagia aspiration related structures improved swallowing function compared standard IMRT. <h3>Methods</h3> DARS was a parallel-group, phase 3, multicentre, randomised,...
6508 Background: Most newly diagnosed oro- & hypopharngeal cancers (OPC, HPC) are treated with (chemo)RT curative intent but at the consequence of adverse effects on quality life. CRUK/14/014 investigated if using Do-IMRT to reduce RT dose dysphagia/aspiration related structures (DARS) improved swallowing function compared S-IMRT. Methods: Patients T1-4, N0-3, M0 OPC/HPC were randomised 1:1 S-IMRT (65 Gray (Gy)/30 fractions (f) primary nodal tumour; 54Gy/30f remaining pharyngeal subsite...
Background The utility of the recently introduced semirigid thoracoscopy in undiagnosed pleural effusions is still unclear. Methods A single-center, 4-year retrospective analysis all medical procedures was done. diagnostic accuracy calculated as number positive diagnoses achieved by relation to end-diagnosis patient group any means. Results One hundred fifty were analyzed. Ninety-two patients (62.3%) diagnosed having a malignant disorder, which mesothelioma most common (26%). Pleural...
A 70-year-old man newly diagnosed with metastatic gastric adenocarcinoma was started on standard first-line palliative chemotherapy anthracycline (epirubicin), platinum (oxaliplatin) and fluoropyrimidine (capecitabine); EOX combination chemotherapy. 5 days after the first cycle of chemotherapy, he presented tachycardia associated severe abdominal lumbar pains. Initial investigations confirmed life-threatening metabolic acidosis serum lactate 9.7 mmol/L (normal range 0.5–2.2 mmol/L). CT...
The COVID-19 pandemic represents a significant disruptor in radiation oncology practice. has altered workflow, patient care, medical education and research. We reflect on important considerations examine the evolving changes across landscape affecting all technologists. Radiation practices have always been led by EBM clinical trials results. This approach is well practised where there sufficient evidence base available competent interpretation of such evidence. challenges this exposing many...
significance in a right level 2 neck node (figures 1B and 2B).At 10 months after treatments, patient remained stable showed no evidence of disease recurrence.Skull base multidisciplinary team (MDT) has scheduled reimaging 3-month time.Patient was kept under an MDT (ENT, Clinical Oncology Ophthalmology) follow-up for every 12 weeks.Adenoid cystic carcinoma is malignancy the salivary glands with mean survival 4.3 years 43-57% patients present lymph metastasis. 1 d-ACC rare variant high-grade...