A5046130078- Advanced MRI Techniques and Applications
- Lanthanide and Transition Metal Complexes
- Immunotherapy and Immune Responses
- Gastrointestinal disorders and treatments
- Metastasis and carcinoma case studies
- Immune Cell Function and Interaction
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- MRI in cancer diagnosis
- Computational Fluid Dynamics and Aerodynamics
- Fluid Dynamics and Turbulent Flows
- Hernia repair and management
- Electron Spin Resonance Studies
- Biliary and Gastrointestinal Fistulas
- Gastrointestinal Tumor Research and Treatment
- Acute Ischemic Stroke Management
- Gallbladder and Bile Duct Disorders
- Abdominal vascular conditions and treatments
- Intracranial Aneurysms: Treatment and Complications
- Fluid Dynamics Simulations and Interactions
- Oral microbiology and periodontitis research
- Chronic Myeloid Leukemia Treatments
- Intestinal and Peritoneal Adhesions
- Appendicitis Diagnosis and Management
- Pancreatic and Hepatic Oncology Research
Osaka University
2018-2024
Tsurugi Hospital
2024
Akita University
2016-2024
Hokkaido University
2013-2024
Okayama Medical Center
2024
Tenri Hospital
2012-2024
Nagano Municipal Hospital
2018-2023
National Cerebral and Cardiovascular Center
2020-2023
Aichi Cancer Center
2021-2022
Saiseikai Suita Hospital
2020
The purpose of the present study was to examine effects restraint stress on periodontal breakdown resulting from Porphyromonas gingivalis-challenged periodontitis in rats.To influence breakdown, rats were orally challenged with pathogen P. gingivalis. Twenty male, specific pathogen-free (SPF) 3-wk-old, Sprague-Dawley divided into four groups: group A (controls), B (exposed for 12 h/d 22 d), C (orally gingivalis), and D d gingivalis). After d, all animals killed. distance alveolar bone crest...
ABSTRACT Prion diseases are fatal neurodegenerative disorders characterized by accumulation of PrP Sc , vacuolation neurons and neuropil, astrocytosis, microglial activation. Upregulation gene expressions innate immunity-related factors, including complement factors CD14, is observed in the brains mice infected with prions even early stage infections. When CD14 knockout (CD14 −/− ) were intracerebrally Chandler Obihiro prion strains, survived longer than wild-type (WT) mice, suggesting that...
In this paper, using full-body CT images of elderly and advanced Japanese cadavers, we measure maxillary other paranasal sinus volumes in order to examine the effects age, sex, presence or absence molars, factors on changes volume. The research subjects consisted 77 95 cadavers donated Kanagawa Dental University between 2012 2014, which average age was 82.6 ± 10 years (33 were male, 79.3 8.3 years, 44 female, 85.1 11.7 years). Sinus volume measured from horizontal plane computed 3D rendering...
Periodontal disease, a pathological destructive inflammatory condition, is characterized by alveolar bone loss. Recent studies have suggested correlation between the sympathetic nervous system and remodeling. To confirm importance of in resorption, we investigated effects superior cervical ganglionectomy oral challenge with Porphyromonas gingivalis on loss rats.Rats were divided into three groups: group A underwent sham operation as control group; B ganglionectomy; C P. gingivalis....
Background Creatine chemical exchange saturation transfer (CrCEST) imaging is expected to be a novel evaluation method of muscular energy metabolism. Purpose To develop CrCEST mouse skeletal muscle and validate this technique by measuring changes in Cr concentration ischemic hindlimbs. Study Type Prospective. Animal Model C57BL/6 mice ( n = 6), mild hindlimb severe 6). Field Strength/Sequence Magnetic resonance angiography (MRA), imaging, phosphorus magnetic spectroscopy 31 P MRS) obtained...
This retrospective study aimed to investigate the validity of a 30-sec chair stand test (CS-30) as simple assess exercise tolerance and clinical outcomes in 53 Japanese patients with esophageal cancer. There was strong correlation between results CS-30 6-min walk (6MWT), gold standard for assessing (r=0.759). Furthermore, fewer whose score greater than 16 (the cutoff value defined based on 6MWT) experienced pneumonia their postoperative course. These suggest that could be assessed using...
This study aimed to evaluate the effect of chemical exchange saturation transfer (CEST) on ischemic regions in hypoxic-ischemic encephalopathy (HIE) comparison with diffusion-weighted imaging (DWI) and magnetic resonance spectroscopy (MRS) using a 7T-MRI.We used neonatal rats (n = 8), aged 8 days, clarify progression HIE. The rat model HIE was developed by ligating severing left common carotid artery, followed 45 minutes recovery, 60 hypoxia (8% O2/92% N2; 34°C). At 0-2 24 hours after onset...
Incadronate (YM175, disodium cycloheptylaminomethylenediphosphonate monohydrate), a bisphosphonate, has been suggested to prevent the bone resorption associated with periodontitis by inhibiting osteoclast activity. The purpose of this study was investigate effect incadronate in preventing periodontal destruction rats Porphyromonas gingivalis-induced periodontitis.Periodontitis induced 35 Wister inoculating P. gingivalis into oral cavity and feeding soft diet for 4 weeks. or placebo...
A Müllerian cyst arising in the posterior mediastinum was initially reported by Hattori 2005. We report a 47-year-old woman with mediastinum, so-called Hattoriʼs cyst. mediastinal mass detected chest X-ray. She exhibited no clinical symptoms associated mass. MRI revealed cystic lesion between Th4/5. Preoperative diagnosis bronchogenic The resected thoracoscopically, and histologic immunohistochemical stainings showed ciliated epithelium that positive for estrogen progesterone receptors....
Perforated appendicitis without an associated abscess necessitates emergency surgery. However, it is difficult to predict the presence of perforation before surgery, and predictive factors are still unclarified. Our purposes were characterize a patient population with perforated identify preoperative appendiceal perforation.We retrospectively identified 150 patients who underwent appendectomy for acute at our institution from June 2018 November 2020. Logistic regression analysis was...
Background When determining treatment strategies for male infertility, it is important to evaluate spermatogenesis and its spatial distribution in the testes. Purpose To investigate usefulness of creatine chemical exchange saturation transfer (CrCEST) imaging evaluating distribution. Study Type Prospective. Animal Model C57BL/6 control mice ( n = 5) model infertility induced by whole testis X‐ray irradiation 11) or localized lower regions testes 3). Field Strength/Sequence A 11.7‐T...
Abstract OBJECTIVES We retrospectively analysed the surgical prognosis of patients with pathological stage I non-small-cell lung cancer (NSCLC) who after complete resection underwent low-dose computed tomography (LDCT) or conventional CT as postoperative surveillance. METHODS investigated 416 lobectomy segmentectomy between January 2013 and December 2016. compared LDCT groups using propensity score-matched analysis. RESULTS The median follow-up period was 57 months. Cancer recurrence...
Intracranial carotid artery dissection causing cerebral ischemia is a rare but important cause of infarction in children and adolescents. Although endovascular therapy has been reported to be effective, questions regarding the indications for intervention are yet addressed. Therefore, this study aimed evaluate factors related clinical outcomes through nationwide survey. Overall, 35 neurosurgical centers patients within 2 weeks after ischemic onset due intracranial treated between January...
Microscopic testicular sperm extraction is the most effective treatment for NOA, but retrieval rate low and depends on maturity. However, there are limited useful tests to assess Chemical exchange saturation transfer (CEST) imaging a new magnetic resonance (MRI) technique that can image distribution of trace substances in vivo. We focused potential role creatine (Cr) testes hypothesized Cr-CEST could indicate intratesticular spermatogenesis.
Background In the management of testicular torsion, estimating duration ischemia is essential for deciding on an appropriate surgical treatment, but there are currently limited evaluation methods. Purpose To perform creatine chemical exchange saturation transfer (CrCEST) imaging and to evaluate its ability accurately estimate ischemia. Study Type Prospective. Animal Model C57BL/6 control mice ( n = 6) models induced by clamping spermatic cord 14). Eight were serially imaged at two or three...
Pseudolymphoma of the liver is a very rare disease. It usually resected and pathologically diagnosed because difficulty discrimination from malignant neoplasm. For this reason, few cases which were observed for several years have been reported. We present case disease slightly enlarged two years. The patient was 46-year-old woman who underwent laparoscopic partial nephrectomy right renal cell carcinoma ago. preoperative computed tomography (CT) showed mass 7 mm in diameter with localized...
Basic fibroblast growth factor (bFGF) is a promising cytokine in regenerative therapy for spinal cord injury. In this study, recombinant canine bFGF (rc-bFGF) was synthesized clinical use dogs, and the ability of rc-bFGF to differentiate bone marrow mesenchymal stem cells (BMSCs) into functional neurons investigated.The using wheat germ cell-free protein synthesis system. The expression mRNA purification process confirmed reverse transcription-polymerase chain reaction (RT-PCR). Western...
Abstract An 84-year-old woman underwent subtotal stomach pancreatoduodenectomy (PD) for distal cholangiocarcinoma. Over 1000 ml of serous ascites, which appeared milky after starting a high-protein, low-fat, middle-chain triglyceride diet, was discharged from the inserted drain. On postoperative day (POD) 13, she right hemicolectomy transverse colonic volvulus, occurred on POD 9 and refractory to conservative therapies. Following second surgery, chylous ascites (CA) amount continued...
Abstract Background Because of its rare indication and relatively simple reconstruction procedure (only choledochojejunostomy gastrojejunostomy) compared to those for pancreatoduodenectomy, the technical tips pitfalls total pancreatectomy are rarely discussed. Herein, we discuss a case gastric volvulus 1 year after provide advice prevent such cases. Case presentation A 66-year-old woman underwent with splenectomy mixed-type intraductal papillary mucinous neoplasm pancreas....