A5044228014- Sarcoma Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Vascular Tumors and Angiosarcomas
- Cancer Immunotherapy and Biomarkers
- Melanoma and MAPK Pathways
- Cutaneous Melanoma Detection and Management
- Microscopic Colitis
- Uterine Myomas and Treatments
- Ovarian cancer diagnosis and treatment
- Urinary and Genital Oncology Studies
- Cervical Cancer and HPV Research
- Pancreatic and Hepatic Oncology Research
- Soft tissue tumor case studies
- Metabolism, Diabetes, and Cancer
- Gastrointestinal Tumor Research and Treatment
- Colorectal Cancer Treatments and Studies
- Urologic and reproductive health conditions
- Diagnosis and treatment of tuberculosis
- Neurofibromatosis and Schwannoma Cases
- Glioma Diagnosis and Treatment
- Endometrial and Cervical Cancer Treatments
- Radiomics and Machine Learning in Medical Imaging
- Neuroendocrine Tumor Research Advances
- Tuberculosis Research and Epidemiology
- Inflammatory Bowel Disease
University of Michigan–Ann Arbor
2020-2025
University of California San Francisco Medical Center
2021
Hershey (United States)
2021
Advances in our understanding of pancreatic ductal adenocarcinoma (PDAC) and its tumor microenvironment (TME) have the potential to transform treatment for hundreds thousands patients who are diagnosed each year. Whereas clinical assessment cancer cell genetics has grown increasingly sophisticated personalized, current protocols evaluate TME lagged, despite evidence that can be heterogeneous within between patients. Here, we outline PDAC diagnosis management, review novel biomarkers,...
Context.— Plexiform fibromyxomas are uncommon gastrointestinal neoplasms that have histologic and molecular features overlap with other mesenchymal tumors present a diagnostic challenge for surgical pathologists. Objective.— To provide review of the clinicopathologic, morphologic, immunohistochemical, plexiform fibromyxomas, brief discussion key aid in differential diagnosis. Data Sources.— Analysis pertinent literature (PubMed) clinical practice experience based on institutional...
The morphologic features of uterine smooth muscle tumors (USMTs) are subject to interobserver variability and complicated by consideration fumarate hydratase deficiency (FHd) other subtypes, with difficult cases occasionally diagnosed as tumor uncertain malignant potential (STUMP). We compare immunohistochemical findings detailed analysis 45 USMTs 4 fellowship-trained gynecologic pathologists comprehensive molecular analysis, focusing on FHd leiomyomas (n=15), compared a variety overlapping...
Diagnosis of spindle cell/sarcomatoid melanoma may be challenging due to frequent loss expression melanocytic marker(s) and histomorphologic resemblance various mesenchymal tumours, particularly malignant peripheral nerve sheath tumour (MPNST). Overexpression PReferentially expressed Antigen in MElanoma (PRAME) supports a diagnosis when evaluating tumours. PRAME MPNST other cutaneous sarcomatoid neoplasms, however, has not been well characterised. We aimed determine the utility immunostain...
Mycobacterial spindle cell pseudotumors (MSPs) are a rare and diagnostically challenging manifestation of non-tuberculous mycobacterial (NTM) infections. Proper recognition these is important because they treatable benign. In this study, we evaluated the morphologic patterns MSPs to improve their pathologic identification. Clinical features 14 were analyzed. Histologic factors included architectural growth pattern spindled or epithelioid macrophages, granulomas location within lesion,...
Metastatic tumors interface with liver in multiple patterns, of which, the rare “sinusoidal” growth pattern can be subtle and easily overlooked on biopsy. We sought to characterize metastasis-to-liver patterns melanoma compared other tumor types assess incidence metastatic histologically normal-appearing targeted lesion biopsies. Liver samples from 54 patients were assessed. Nearly cases, defined as no obvious malignancy routine hematoxylin eosin stain (n=24), stained SOX10 confirmed MelanA....
Insulinomas are rare in the post-bariatric surgery setting. The differential diagnosis for hypoglycemia is broad, requiring laboratory testing to verify endogenous hyperinsulinemic hypoglycemia. Selective arterial calcium stimulation (SACST) can help localize abnormal insulin production. We describe a patient with histologically confirmed insulinoma after bariatric diagnosed aid of SACST.We present 67 year old woman history Roux-en-Y bypass who presented Initially, no pancreatic lesion was...