A5017677004- Congenital Heart Disease Studies
- Congenital heart defects research
- Cardiomyopathy and Myosin Studies
- Congenital Diaphragmatic Hernia Studies
- Tracheal and airway disorders
- Cardiovascular Effects of Exercise
- Cardiovascular Issues in Pregnancy
- Neurogenetic and Muscular Disorders Research
- Pregnancy and preeclampsia studies
- Cardiac Structural Anomalies and Repair
- Vascular anomalies and interventions
- Myasthenia Gravis and Thymoma
- Vascular Procedures and Complications
- Cardiovascular Function and Risk Factors
- Birth, Development, and Health
- Gestational Diabetes Research and Management
- Esophageal and GI Pathology
- Central Venous Catheters and Hemodialysis
- Lymphatic Disorders and Treatments
- Cardiac Valve Diseases and Treatments
- Viral Infections and Immunology Research
- Cardiovascular Conditions and Treatments
- Coronary Artery Anomalies
- Kawasaki Disease and Coronary Complications
- Immunodeficiency and Autoimmune Disorders
Fukuoka Children's Hospital and Medical Center for Infectious Diseases
2018-2024
Hospital for Sick Children
2015-2017
University of Toronto
2017
National Sagamihara Hospital
2011
Abstract Objective Mothers carrying anti‐Ro antibodies are frequently referred for weekly echocardiograms to early detect and treat antibody‐mediated fetal heart disease. We tested a surveillance strategy based on antibody titers. Methods From 2009 2014, 232 pregnancies were maternal antibodies. At the baseline echocardiogram, titers measured by enzyme‐linked immunosorbent essay results categorized as negative (<8 U/mL; n = 43; excluded), low–moderate positive (8–49 62; group 1) or high...
A preschool male patient with an extensive cardiac surgical history developed refractory chylothorax after a total cavopulmonary connection. Neither lymphoscintigraphy nor single-photon emission computed tomography (SPECT)/computed could identify the lymphatic system leakage sites. Non-contrast heavy T2-weighted magnetic resonance lymphangiography (MRL) was performed to visualize system. Nevertheless, distinguishing ducts from other watery structures of remained difficult. Therefore,...
Abstract Background Dilated cardiomyopathy (DCM) is a progressive myocardial disorder characterized by impaired cardiac contraction and ventricular dilation. Some patients with DCM could manifest improvement in these abnormalities called left reverse remodeling (LVRR). However, the detailed association between genotypes clinical outcomes, including LVRR, particularly among pediatric patients, remains uncertain. Methods We prospectively enrolled from Japanese multi-institutional centers 2014...
ВОЗМОЖНОСТИ МАГНИТНО-РЕЗОНАНСНОЙ ТОМОГРАФИИ В ОПРЕДЕЛЕНИИ ПРЕДПОЛАГАЕМОЙ МАССЫ ПЛОДАСыркашев Е.М. 1 , Кан Н
Abstract Background: Dilated cardiomyopathy (DCM) is a progressive myocardial disorder characterized by impaired cardiac contraction and ventricular dilation. However, some patients with DCM improve when experiencing left reverse remodeling (LVRR). Currently, the detailed association between genotypes clinical outcomes, including LVRR, particularly among children, remains uncertain. Methods: Pediatric from multiple Japanese institutions recorded 2014 2023 were enrolled. We identified their...
Abstract Cardiovascular magnetic resonance T1 and T2 mapping reflects inflammation, fibrosis, myocardial oedema. However, its application in infants remains uncertain. Herein, we report a three-month-old boy with dilated cardiomyopathy successfully treated steroids. was useful for diagnosis based on the elevated native T1, T2, extracellular volume evaluation of response to immunosuppressive therapy infantile inflammatory cardiomyopathy.
Background Left ventricular noncompaction (LVNC) is a hereditary type of cardiomyopathy characterized by prominent trabeculations. Detailed characteristics biventricular (BiVNC) remain unknown. This study aimed to elucidate the clinical and genetic landscape BiVNC. Methods Results We recruited children with left from Japanese multi‐institutional centers 2013 2021. was classified as BiVNC, congenital heart disease, arrhythmia, dilated cardiomyopathy, or normal function. In these patients,...
Dilated cardiomyopathy (DCM) is a progressive myocardial disorder characterized by impaired cardiac contraction and ventricular dilation. However, some patients with DCM improve when experiencing left reverse remodeling (LVRR). Currently, the detailed association between genotypes clinical outcomes, including LVRR, particularly among children, remains uncertain. Pediatric from multiple Japanese institutions recorded 2014 2023 were enrolled. We identified their DCM-related genes explored gene...
Abstract We present the second reported case of left pulmonary artery sling with dextrocardia, right hypoplasia, and total venous connection in a fetus. This highlights importance determination arrangement by fetal echocardiography if hypoplasia and/or congenital heart disease is suspected.
Abstract Aim: To determine the current status of fetal CHD screening in our region and to establish a system Japan. Material Methods: Subjects were 168 fetuses prenatally‐diagnosed with at four referral centers Japan from 2003 2007. divided into two groups: group A ( n = 84) included cases without extracardiac sonographic abnormalities known risk factors for B those or factors. The diagnostics outcomes between groups analyzed. Results: There more single ventricle restrictive ductus...
Pericatheter thrombus calcification is a complication that arises due to central venous catheter insertion and particularly rare in peripherally inserted catheters (PICCs). In this case report, we reviewed the clinical course of two neonates experiencing calcification. The first involved male neonate weighing 445 g. His PICC dwelt superior vena cava for over 49 days. Although radiograph after removal did not show any silhouette, subsequent radiographs CT depicted catheter-like outline....
Exposure of the fetus to maternal anti-Ro autoantibodies (AB) is main etiology congenital complete heart (CHB) and endocardial fibroelastosis (EFE). Because perception that these immune-mediated conditions may be preventable if treated at an early disease stage, weekly echocardiograms during period highest fetal risk CHB recommended mothers with a positive AB test. In earlier study, we found all children had high antibody levels concluded serial should limited women levels. This prospective...
Vici syndrome is an autosomal recessive disorder involving autophagy dysfunction caused by the biallelic pathogenic variants in ectopic P-granules 5 tethering factor (EPG5). The prevalence of reported to be less than 1/1,000,000. Fetal ultrasonography detected right ventricular hypertrophy and hypoplastic left ventricle. After birth, hypopigmentation, agenesis corpus callosum, cerebellar hypoplasia, progressive dysphagia were confirmed. Right was ameliorated after delivery. In addition,...
胎児心エコー検査は先天性心疾患の胎児診断と周産期管理方針を決めるうえで不可欠な検査である．胎児の位置や向きは常に変化するためプローブを当てる位置・動かし方は一定でなく，胎児診断のための基本断面を描出するには生後の心エコーと異なるテクニックが必要となる．胎児心エコー検査は主に水平断面スキャンをして心臓と両大血管を評価することが基本であるため，上達するには〈きれいな四腔断面〉〈観察しやすい四腔断面〉を描出するテクニックを習得するとよい．それらテクニックを利用して胎児心臓の〈きれいな基本断面〉を描出できるようになれば，小児循環器科医が持つ知識を利用してプローブの動かし方を少し変えるだけで複雑心奇形の診断も自信をもって行えるようになる．