A5071952626- Epilepsy research and treatment
- Neuroscience and Neuropharmacology Research
- Pharmacological Effects and Toxicity Studies
- Phytoestrogen effects and research
- Menopause: Health Impacts and Treatments
- Parkinson's Disease Mechanisms and Treatments
- Estrogen and related hormone effects
- Traumatic Brain Injury and Neurovascular Disturbances
- Melanoma and MAPK Pathways
- Physical Education and Gymnastics
- Neurological disorders and treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological Disease Mechanisms and Treatments
- Neurological Disorders and Treatments
- Spinal Cord Injury Research
- Trypanosoma species research and implications
- Aluminum toxicity and tolerance in plants and animals
- Alcoholism and Thiamine Deficiency
- Traumatic Brain Injury Research
- Sports Performance and Training
- Birth, Development, and Health
- Healthcare during COVID-19 Pandemic
- Trace Elements in Health
- Metabolism and Genetic Disorders
- Heavy Metal Exposure and Toxicity
Universidade Federal de Santa Catarina
2013-2020
Governador Celso Ramos Hospital
2017
University of Florida
2016
Colciencias
2014
Universidade Federal do Rio Grande do Sul
2008-2011
Reduction of cerebral blood flow is an important risk factor for dementia states and other brain dysfunctions. In present study, the effects permanent occlusion common carotid arteries (2VO), a well established experimental model ischemia, on memory function were investigated, as assessed by reference working spatial protocols object recognition task; cell damage to hippocampus, measured through changes in immunoreactivity GFAP neuronal marker NeuN was also studied. The hypothesis that...
Physical activity impacts functional recovery following stroke in humans, however its effects experimental animals submitted to chronic cerebral hypoperfusion have not been investigated. The aim of this study was evaluate the therapeutic potential exercise, as assessed by cognitive Morris water maze and brain oxidative status, through measurement macromolecules damage, TBARS levels total cellular thiols, well antioxidant enzymes hippocampus, striatum cortex. Adult male Wistar rats were...
To investigate prospectively the independent predictors of a minimum clinically important change (MCIC) in quality life (QOL) after anterior temporal lobectomy (ATL) for drug-resistant mesial lobe epilepsy related to hippocampal sclerosis (MTLE-HS) Brazilian patients.Multiple binary logistic regression analysis was performed identify clinical, demographic, radiologic, and electrophysiologic variables independently associated with MCIC Quality Life Epilepsy-31 Inventory (QOLIE-31) overall...
Since previous studies have shown that ovariectomy impairs memory and cognition, we investigated whether physical exercise would affect ovariectomy-induced deficits in inhibitory avoidance Morris water maze tasks. Female adult Wistar rats were assigned to one of the following groups: sham (submitted surgery without removal ovaries), exercise, (Ovx) Ovx plus exercise. Thirty days after or surgery, animals submitted 1 month treadmill training for 20 min, three times per week. Rats than tested...
Introduction: Changes in hormone blood levels during the acute phase of traumatic brain injury (TBI) have been described literature. The objective was to investigate association among several hormones plasma severe TBI and hospital mortality rate male patients.Methods: independent TSH, LH, FSH, GH, free T4, cortisol, IGF-1 total testosterone measured 10 hours 30 after 60 consecutive patients evaluated.Results: At least one hormonal level abnormality demonstrated 3.6–73.1% patients. multiple...
Parkinson's disease (PD) is an age-related neurodegenerative disorder characterized by the slow and progressive death of dopaminergic neurons in (substantia nigra pars compact). Hypericum perforatum (H. perforatum) a plant widely used as antidepressant, that also presents antioxidant anti-inflammatory properties. We evaluated effects H. on turning behavior rats submitted to unilateral administration 6-hydroxydopamine (6-OHDA) into medial forebrain bundle animal model PD. The animals were...
ABSTRACT Sleepiness and cognitive impairment are common symptoms observed in patients with epilepsy. We investigate whether self-reported sleepiness is associated performance refractory mesial temporal lobe epilepsy hippocampal sclerosis (MTLE-HS). Seventy-one consecutive MTLE-HS were evaluated the Stanford Scale (SSS) before neuropsychological evaluation. Their mean SSS scores compared controls. Each test was between (SSS ≥ 3) or without < 3). Imbalances controlled by regression...