A5016150952- Plant biochemistry and biosynthesis
- Nanoplatforms for cancer theranostics
- Advanced Nanomaterials in Catalysis
- Natural product bioactivities and synthesis
- Epigenetics and DNA Methylation
- Gut microbiota and health
- Helicobacter pylori-related gastroenterology studies
- Nuts composition and effects
- Extracellular vesicles in disease
- Nanocluster Synthesis and Applications
- MXene and MAX Phase Materials
- Gaze Tracking and Assistive Technology
- Cancer-related molecular mechanisms research
- Probiotics and Fermented Foods
- RNA modifications and cancer
- Advanced Photocatalysis Techniques
- African Botany and Ecology Studies
- Opioid Use Disorder Treatment
- Clostridium difficile and Clostridium perfringens research
- Machine Learning in Materials Science
- Anesthesia and Pain Management
- Pain Management and Opioid Use
- Gastrointestinal motility and disorders
- Diabetes Management and Research
- Robotics and Automated Systems
Tongliao Academy of Agricultural Sciences
2025
Shanghai Children's Medical Center
2024
Shanghai Jiao Tong University
2024
Tianjin People's Hospital
2014-2024
Central South University
2020-2023
Southeast University
2023
Guangzhou Medical University
2021-2022
Guangzhou First People's Hospital
2021-2022
Curtin University
1997-2022
South China University of Technology
2021-2022
Chronic gastritis is one of the most common findings at upper endoscopy in general population, and chronic atrophic epidemiologically associated with occurrence gastric cancer. However, current status diagnosis treatment China unclear. A multi-center national study was performed; all patients who underwent diagnostic for evaluation gastrointestinal symptoms from 33 centers were enrolled. Data including sex, age, endoscopic prospectively recorded. Totally 8892 included. At endoscopy, 4389,...
The development of highly effective and minimally invasive approaches for cancer treatment is the ultimate goal.
Photothermal therapy (PTT) is a powerful strategy for cancer treatment with minimal invasiveness but still limited by lack of long-term efficacy against tumor recurrence and toxicity concerns about the slow biodegradability PTT agents. Herein, an injectable hydrogel platform (R848/POM@GG) gellan gum co-loaded Dawson-type {P2Mo18} polyoxometalate (POM) Toll-like receptors agonist resiquimod (R848) developed combinational photothermal-immunotherapy cancer. The POM-based (POM@GG) exhibits high...
Stand-alone perception systems in autonomous driving suffer from limited sensing ranges and occlusions at extended distances, potentially resulting catastrophic outcomes. To address this issue, collaborative is envisioned to improve perceptual accuracy by using vehicle-to-everything (V2X) communication enable collaboration among connected vehicles roadside units. However, due resources, it impractical for all units transmit data such as point clouds or high-definition video. As a result,...
Naked oats offer substantial nutritional and health benefits, primarily due to their main dietary fiber component, soluble β-(1,3)(1,4)-D-glucan (β-glucan). In a pool experiment, humic acid (HA) was applied once during both the booting anthesis stages at varying irrigation amounts (60 mm, 120 180 mm) assess changes in β-glucan content grains post-anthesis. Results indicated that 5 days post-anthesis (DPA), (3.14% W/W) increased by 16%with application of HA, compared control treatment...
The principal study objective was to investigate the pharmacokinetic characteristics of a new sublingual ketamine wafer and establish its absolute bioavailability local tolerability.The open label, two way randomized crossover design in eight healthy male volunteers. Each participant received either single 10 mg intravenous dose as constant rate 30 min infusion or 25mg treatment periods with 7 day wash out. Pharmacokinetic blood sampling tolerability safety assessments were carried out...
An injectable gellan gum-based nanocomposite hydrogel (Bi2S3@GG) was designed for X-ray computed tomography (CT) imaging and photothermal/antiangiogenic therapy. The linear anionic polysaccharide gum (GG) used as a stabilizer, embedded with ultra-small bismuth sulfide (Bi2S3) nanodots (∼2 nm) through one-pot synthesis method. as-prepared Bi2S3@GG displays excellent capability both photothermal therapy (PTT) (with conversion efficiency of 44.3%) an absorption coefficient 51.5 HU L g-1),...
Sandalwood seed oil improved insulin resistance by activating the PI3K/AKT signaling pathway and down-regulating JNK/NF-κB inflammatory in liver.
Clinical significance of micro ribonucleic acid (miR)-24 and miR-101 were investigated by evaluating the expression miR-24 in tissues patients with advanced gastric cancer. A total 247 cancer tissue specimens 150 cancer-adjacent normal (>5 cm away from tumor) who underwent surgical resection Surgical Oncology Department Tianjin Union Medical Centre (Tianjin, China) April 2013 to May 2016 collected. The detected via reverse transcription-quantitative polymerase chain reaction (RT-qPCR),...
A powerful minimally invasive approach holds great promise toward the treatment of solid tumors in aims reducing systemic toxicity drugs and risk infections surgeries. Herein, we design a PLEL-based thermosensitive nanocomposite micellar hydrogel delivery platform, which two-dimensional nanosheet-based photothermal agent vascular disrupting (combretastatin A4, CA4) are loaded for synergistic antitumor therapy. Ultrathin Ti3C2 MXene with thickness less than 5 nm is synthesized through...
The aim of the present study was to investigate effect sandalwood seed oil on fatty acid (FA) profiles and inflammatory factors in rats. Fifty male Sprague-Dawley rats were randomly divided into five different dietary groups: 10 % soybean (SO), olive (OO), safflower (SFO), linseed (LSO) 8 blended with 2 SO (SWSO) for weeks. SWSO group had a higher total n-3 polyunsaturated acids (PUFA) levels but lower n-6:n-3 PUFA ratios both adipose tissue liver than those SO, OO SFO groups (p < 0.05)....
Abstract MXene, a family of two-dimensional transition metal carbides/nitrides, is one the most attractive photothermal materials due to its unique hydrophilicity, tunable surface activity, and outstanding conversion performance by absorbing near-infrared light or solar light. The integration MXene into three-dimensional polymer hydrogels opens up new possibilities for developing advanced material platforms. In this review, we summarize synthesis MXene-based highlight their recent progress...
Gastric cancer (GC) is one of the most prevalent cancers globally. This study was designed to evaluate potential performance plasma SEPT9 methylation (mSEPT9) as a noninvasive biomarker for diagnosis GC.A total 182 participants, i.e., 60 patients with GC, 39 chronic superficial gastritis (CSG), 27 atrophic (CAG), 30 gastric ulcer (GU), and 26 polys (GP), were recruited. The mSEPT9 level measured using real-time polymerase chain reaction.As diagnostic target, (1/3 algorithm) had sensitivity...
Patients with metastatic colorectal cancer cannot receive adequate therapy due to their general bad condition, which is at least one of the reasons resulting in poor prognosis. The aim this study was evaluate efficacy and safety use DC vaccine combined oral Capecitabine patients cancer; these two methods are commonly used separately as monotherapy.All 17 received orally twice daily 1,250 mg/m2. One cycle included weeks treatment followed by week's rest. Concurrently, all 1x107 tumor...
Background . Functional gastrointestinal disorder (FGID) patients are influenced by anxiety, depression, and low sleep quality, which reduce the quality of their life. However, epidemiological data on in FGID were lacking. This study aims to explore influencing factors patients. Methods 1200 subjects, diagnosed as one six class-three hospitals Tianjin, China, from January December 2014, recruited. The information about demographic information, severity clinical symptoms, psychological status...
Methylated syndecan2 (mSDC2) in stool samples has been found to be associated with colorectal cancer (CRC) and precancerous lesions. However, the available data are limited, no previous studies have compared analysis of mSDC2 other diagnostic tests. Thus, we aimed evaluate clinical performance a test compare its that blood-based tests for methylated septin9 (mSEPT9), carcinoembryonic antigen (CEA), carbohydrate 19-9 (CA19-9) 724 (CA724) detecting neoplasms.The gold standard technique was...
Paraclostridium bifermentans is the most diverse distributed species of and can cause fatal human infections under rare conditions. However, its pathogenic mechanisms adaptation ability behind remain unclear. Herein, we reported complete genome sequence P. HD0315_2 isolated from feces a patient with Crohn's disease. Then, performed genomic analyses to understand ability.The de novo assembly revealed that strain carried circular chromosome 3.27 Mb six plasmids (19.41 139.50 kb). The...
Abstract Western Australian Sandalwood (Santalum spicatum R.Br.) is an economically important timber crop. seeds have been identified as a potential secondary source of income prior to harvesting the tree. Chemical and toxicological studies seed found that kernels contain nearly 50% drying oil. This oil comprised mainly unsaturated fatty acids. The presence unusual acetylenic acid has confirmed. was cause no pathological abnormalities in mice but reduced fat deposition. Acetylenic acids are...
Apomorphine in solution undergoes rapid autoxidation, producing greenish colored solutions, making it difficult to formulate as a stable pharmaceutical solution. To identify the optimum antioxidant agent/combination for apomorphine solution, high performance liquid chromatography assay was used study stability of 50 μg/mL HCI 0.1% L-ascorbic acid (AA), sodium metabisulfite (SMB), EDTA, and selected combinations at 25°C, 32°C, 37°C over period 14 days. The HCl (10 mg/mL) AA EDTA 25°C also...
The aim of this study was to prepare poly(d, l-lactide) (PLA) microspheres containing naltrexone (NTX) by a solvent evaporation method, and evaluate both in vitro vivo release characteristics histopathological findings tissue surrounding an implant formulation rats.This method enabled the preparation regular shape relatively narrow particle size distribution. profiles NTX from PLA showed did not follow zero-order kinetics. An initial burst observed, subsequently followed nearly constant rate...
Ximenynic acid is a conjugated enyne fatty acid, which currently of interest due to its anti-inflammatory activity. Due the association between inflammation and cancer, present study was designed investigate anti‑cancer activity ximenynic in HepG2 human hepatoma cell line underlying mechanisms. The current demonstrated anti‑proliferation pro‑apoptosis activities by viability assay flow cytometry analysis. expression anti‑apoptosis protein silent information regulator T1 (SIRT1) significantly...
Sandalwood (Santalum spicatum) seed oil, which occurs to about 50% of the weight kernels, contains 30-35% total fatty acids (FA) as ximenynic acid (XMYA). This study was designed obtain basic information on changes in tissue FA composition and metabolic fate XMYA mice fed a sandalwood oil (SWSO)-enriched diet. Female were randomly divided into three groups, each receiving different semisynthetic diets containing 5.2% (w/w) fat (standard laboratory diet), 15% canola or SWSO for 8 wk. The...
Background. RNF180 is a tumor suppressor gene involved in cell development, proliferation, and apoptosis. Methylation of (mRNF180) leads to low expression RNF180, which closely related the occurrence development gastric cancer (GC). This study was designed evaluate potential performance plasma mRNF180 as noninvasive biomarker for diagnosis GC. Methods. A total 156 participants, including 60 patients with GC, 39 chronic superficial gastritis (CSG), 27 atrophic (CAG), 30 ulcer (GU) were...