A5100375816- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Medical Imaging and Analysis
- Spinal Fractures and Fixation Techniques
- Anesthesia and Pain Management
- Lymphoma Diagnosis and Treatment
- Vitamin D Research Studies
- Bone health and treatments
- Fire Detection and Safety Systems
- RNA Research and Splicing
- Breastfeeding Practices and Influences
- Cancer-related molecular mechanisms research
- IoT-based Smart Home Systems
- Pain Mechanisms and Treatments
- Spinal Hematomas and Complications
- Amoebic Infections and Treatments
- Sexual Differentiation and Disorders
- Congenital Anomalies and Fetal Surgery
- Phytoestrogen effects and research
- Bone health and osteoporosis research
- Cancer Immunotherapy and Biomarkers
- Orthopaedic implants and arthroplasty
- Parasitic infections in humans and animals
- Cryospheric studies and observations
- Gestational Diabetes Research and Management
Northwest University
2022-2024
Xinjiang Medical University
2022-2023
Orthopaedic Center
2022-2023
Shanghai Sixth People's Hospital
2023
Shanghai Jiao Tong University
2010-2023
Shaanxi University of Technology
2022
Tianjin Medical University
2018-2022
Tianjin First Center Hospital
2018-2022
Tianjin University of Technology
2016-2020
Université Paris 8
2020
Vitamin D and vitamin receptor (VD/VDR) plays a vital role in the development of spermatozoa, which is largely determined by testosterone level serum. Testosterone biosynthesis closely related to lipid metabolism gonadal adipose around testes. VDR could regulate adipocytes as well. However, it still remains unknown how regulates impact testis. Hereby, various parameters male fertility were compared between wildtype (WT) Vdr knockout (Vdr-KO) mouse. For Vdr-KO mice, size testis was smaller...
Intervertebral disc degeneration (IDD) has been identified as one of the predominant factors leading to persistent low back pain and disability in middle-aged elderly people. Dysregulation Prostaglandin E2 (PGE2) can cause IDD, while low-dose celecoxib maintain PGE2 at physiological level activate skeletal interoception. Here, nano fibers have extensively used treatment novel polycaprolactone (PCL) loaded with were fabricated for IDD treatment. In vitro studies demonstrated that had ability...
In this study, we examined the association between soy isoflavones and lipid profiles, apolipoprotein levels in patients with type 2 diabetes China. The study population was composed of 120 cases (80 women 40 healthy women). Objects treatment group received 435 mg/day for months, then profiles were analyzed by colorimetry method determined immune turbidimetric method. And all indexes after oral glucose tolerance test. total cholesterol, triglyceride LDL-C significantly reduced HDL-C A1...
Abstract Background Investigate the biomechanical properties of hybrid fixation technique with bilateral pedicle screw (BPS) and modified cortical bone trajectory (BMCS) in L4-L5 transforaminal lumbar interbody fusion (TLIF). Methods Three finite element (FE) models L1-S1 spine were established according to three human cadaveric specimens. BPS-BMCS (BPS at L4 BMCS L5), BMCS-BPS (BMCS BPS BPS-BPS BMCS-BMCS L5) implanted into segment each FE model. The range motion (ROM) segment, von Mises...
Facet tropism and orientation are thought to be associated with lumbar disc herniation (LDH), but the relationship is not well established. Moreover, effect of facet joint on LDH has been outlined in young patients. The objective this study was investigate associations patients (18-35 years) by computed tomography (CT). Fifty-three 129 neither nor low back pain were included study. angles measured for each CT as per method described Noren et al. We defined a bilateral angle difference > 5°....
Although the incidence and cure rate of spinal hydatidosis are low, recurrence is high, prognosis poor. Therefore, we report a typical case refractory to increase spine surgeons' awareness disease reduce misdiagnosis recurrence.A 48-year-old man presented with back pain, significant weight loss, paralysis both lower limbs. The patient was misdiagnosed tuberculosis in an outside hospital. However, magnetic resonance imaging (MRI) showed hyperintense cystic components on T2-weighted images...
This project is based on quad-rotor Unmanned aerial vehicle (UAV), which made of ARM embedded system and STM32F1 series 32-bit micro-control Mono-Chip Computer. Under the framework operating UC/OS, to replace staff workers, this UAV employed conduct detecting noxious gas through all kinds sensors. With use wireless transmission technology, it possible real-time communication with mobile phone, assist ground complete detection work auxiliary undertake safety assessment, such as exploring...
Colorectal cancer (CRC) is the third most common and fourth leading cause of mortality, twin studies have shown that approximately 35% variation in susceptibility to CRC involves inherited genetic differences. We sought investigate potential associations between some single nucleotide polymorphisms (SNPs) risk Chinese Han population.We conducted a case-control study including 269 cases 309 controls. Sixteen SNPs associated with were selected from previous genome-wide association genotyped...
Objective To determine whether lumbar anatomy parameters are in dynamic change and related factors. Methods This is a retrospective study. Participants who did computed tomography (CT) scanning Shandong University Qilu Hospital from October 2017 to March 2019 were selected. The 476 participants randomly selected as male or female, with the age ranging 17 87 years (mean, 55.19; standard deviation, 14.28 years). All measurements taken based on CT image measurement of morphology was conducted...
Lumbar spinal stenosis is conventionally treated with surgical decompression. However, bilateral decompression and laminectomy more invasive may not be necessary for lumbar patients unilateral radiculopathy. We aimed to report the outcomes of pedicle screw fixation fusion radiculopathy.Patients lower extremity radiculopathy who received limited were included evaluated using visual analog scale (VAS) pain Oswestry Disability Index (ODI) scores preoperatively at follow-up visits. Ligamentum...
Background Ocular adnexal lymphoma (OAL) and idiopathic orbital inflammation (IOI) are malignant benign lesions for which radiotherapy corticosteroids indicated, but similar clinical manifestations make their differentiation difficult. Purpose To develop validate an MRI‐based radiomics nomogram individual diagnosis of OAL vs. IOI. Study Type Retrospective. Population A total 103 patients (46.6% female) with mean age 56.4 ± 16.3 years having ( n = 58) or IOI 45) were divided into independent...
To evaluate the ratcheting behavior of intervertebral discs (IVD) by experiments and theoretical study.The lumbar spines sheep were obtained at a local slaughterhouse, IVD was processed with upper lower vertebral bodies (about 5 mm) to ensure mechanical state in situ. The tests uniaxial cyclic compression loading for disc samples is carried out using Electronic Universal Fatigue Testing System room temperature. effects different stress variations, rates, as well segments on investigated.The...
Lumbar disc herniation is considered to be the main pathological factor for common clinical disease of low back pain. Biomechanical an important cause lumbar herniation, so it urgent analyze stress/strain behavior intervertebral under different loading condition. Slow repetitive spine and injuries, effect fatigue load on internal displacement in was investigated by applying optimized digital image correlation technique this study. The first finding that had a significant distribution...
To compare the CT values and length of screw tracks traditional trajectory (TT), cortical bone (CBT), modified (MCBT) screws investigate effects on biomechanics lumbar fixation.CT scan data 60 L4 L5 spine were retrieved divided into 4 groups (10 male 10 female cases in 20-30 years old group 20 30-40 group). 3-dimentional (3D) model established using Mimics 19.0 for each placement three techniques was simulated L5, part occupied by track set as region interest (ROI). The mean value actual...
BACKGROUND: The effect of anti-osteoporosis treatment in elderly patients with osteoporosis and lumbar discectomy fusion (LIF) for degenerative diseases is not well known. OBJECTIVE: This study aimed to evaluate the perioperative LIF. METHODS: From January December 2022, were divided into three groups according inclusive criteria: normal group (Group A), osteopenia B) C). Quantitative computed tomography (QCT), height intervertebral space (HIS), segmental sagittal angle (SSA), visual...
The occurrence of lumbar disc herniation is closely related to the mechanical state, and it necessary study internal behavior intervertebral under different loading conditions. In this study, unconfined experiments were conducted by applying an optimized Digital Image Correlation (DIC) technique, displacement was analysed for axial compression with flexion position. It found that average compressive in posterior AF, outer region significantly lower than inner region, while upper region....
Purpose Cervical disc herniation (CDH) is one of the most common spinal diseases in modern society; intervertebral degeneration (IVDD) has long been considered as its primary cause. However, mechanism still unclear. The aim study to examine components and structures proteoglycan collagen cervical herniated nucleus pulposus (NP) using a validated convenient Raman spectra technique histological methods further elucidate IVDD at microscopic level. Methods Our used burgeoning spectroscopy...
Abstract Background:: Investigate the biomechanical properties of hybrid fixation technique with bilateral pedicle screw (BPS) and modified cortical bone trajectory (BMCS) in L4-L5 transforaminal lumbar interbody fusion (TLIF). Methods: Three finite element (FE) models L1-S1 spine, including seven ligaments facet joint cartilage were established according to four human cadaveric specimens. BPS-BMCS (BPS at L4 BMCS L5), BMCS-BPS (BMCS BPS BPS-BPS BMCS-BMCS L5) implanted into segment each FE...
The aim of this study was to investigate the clinical effect direct isthmus repair via Wiltse approach and classical in treatment simple lumbar spondylolysis young patients. Thirty-three patients with underwent isthmic (n = 17) or 16). operation time, intraoperative blood loss, postoperative drainage volume, hospital stay, fusion rate, visual analogue scale (VAS), Oswestry disability index were evaluated compared between 2 groups. amount duration stay group lower than those (P < .05). There...
The intervertebral disc (IVD) was vulnerable to injury or early degenerative lesions. Although much research has been addressed investigate the mechanical properties of discs, such as compression, tension and bending, there little on behavior IVD under cyclic compression. purpose this study response discs physiological loads, effects pressure peak rate IVDs. results showed that loading displacement sheep lumbar decreases with increase number cycles is both stage transient reduction...