A5100317722- Mycobacterium research and diagnosis
- Cancer Mechanisms and Therapy
- Tuberculosis Research and Epidemiology
- Hepatocellular Carcinoma Treatment and Prognosis
- Gastric Cancer Management and Outcomes
- interferon and immune responses
- PI3K/AKT/mTOR signaling in cancer
- Ferroptosis and cancer prognosis
- Heart Rate Variability and Autonomic Control
- Melanoma and MAPK Pathways
- Cardiac Structural Anomalies and Repair
- Cholesterol and Lipid Metabolism
- Surgical Sutures and Adhesives
- Dermatologic Treatments and Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Surgical Simulation and Training
- Vascular Procedures and Complications
- NF-κB Signaling Pathways
- Healthcare and Venom Research
- Toxic Organic Pollutants Impact
- DNA and Nucleic Acid Chemistry
- Laser Applications in Dentistry and Medicine
- Cardiovascular Disease and Adiposity
- Natural Antidiabetic Agents Studies
- Heart Failure Treatment and Management
Tianjin International Joint Academy of Biomedicine
2016-2025
Xuzhou Central Hospital
2024
Sichuan University
2022-2023
West China Second University Hospital of Sichuan University
2022
Dalian Medical University
2018-2021
Second Affiliated Hospital of Dalian Medical University
2018-2021
China Pharmaceutical University
2020
Guangdong Provincial People's Hospital
2019
Ministry of Education of the People's Republic of China
2017
The 309th Hospital of Chinese People's Liberation Army
2011-2015
To study the corneal epithelial and stromal thickness profile changes after photorefractive keratectomy (PRK) for myopia.Retrospective analysis of postoperative in 46 left eyes patients treated with PRK myopia. Corneal maps within central 6 mm were obtained by anterior segment spectral-domain optical coherence tomography preoperatively at 1, 3, months postoperatively. Stromal was calculated subtracting from total thickness. Correlations between amount correction, treatment zone, preoperative...
Introduction: Hepatocellular carcinoma (HCC) is one of the most common malignant tumors globally. Macrophages, as essential components immune system, play crucial roles in regulation, inflammation modulation, and antitumor activity. However, it remains unclear whether tumor-associated macrophages can serve prognostic markers for HCC. Methods: First, we identified based on single-cell data from GSE140228. Then, using a machine learning approach with combination 101 module genes, constructed...
Abstract TIFA, also called T2BP, was first identified using yeast two-hybrid screening. Our previous work showed that TIFA suppresses hepatocellular carcinoma (HCC) progression via apoptosis and cell cycle arrest. However, the mechanism by which this suppression occurs remains unclear. Here we demonstrated TIFA-induced demonstrates two distinct time patterns (i.e., at 48 h >7 days) when reconstitution occurs. Moreover, found MALT1 (a competitor of TIFA) plays a crucial role in...
Five peptidomimetic prodrugs of didanosine (DDI) were synthesized and designed to improve bioavailability DDI following oral administration via targeting intestinal oligopeptide transporter (PepT1) enhancing chemical stability. The permeability was screened in Caco-2 cells grown on permeable supports. 5'-O-L-valyl ester prodrug (compound 4a) demonstrated the highest membrane selected as optimal target for further studies. uptake glycylsarcosine (Gly-Sar, a typical substrate PepT1) by could...
Objective This study aimed to explore the effectiveness and applicability of a psychological intervention using virtual reality (VR) reduce preoperative anxiety in patients undergoing carotid artery stenting (CAS). Methods A total 114 aged 18–86 years who were scheduled undergo CAS randomized VR control groups. Patients group used headset view 16-min video, while those tablet for viewing. The primary assessment instrument was State Anxiety Inventory (S-AI), which given 20 min before after 24...
Background and Objectives Laser therapy during the early stage of wound healing can reduce surgical scar formation. Previous clinical trials showed that ablative fractional laser (AFL) might have achieved best outcomes; however, there was no consensus on protocol. The current study investigated efficacy intervention with carbon dioxide FL (CO 2 FL) in reducing scars patients all age groups to understand effects specific timing, light dose, number treatments, treatment interval therapeutic...
WNK lysine deficient protein kinase 4 (WNK4) has been shown to be significantly associated with cancer progression. Nevertheless, its involvement in gastric (GC) is unclear. The objective of this work was investigate the WNK4's regulatory mechanism GC. Quantitative RT-PCR and immunoblots revealed that WNK4 expression downregulated GC low strongly linked poor prognosis. Functional assays including cell counting kit-8 assay colony formation demonstrated overexpression led limited tumor...
Random peptide libraries displayed on the ribosome are becoming a new tool for in vitro selection of biologically relevant macromolecules, including epitopes, antagonists, enzymes, and cell-surface receptors. Ribosome display is cell-free system coupling individual nascent proteins (phenotypes) to their corresponding mRNA (genotypes) by formation stable protein-ribosome-mRNA complexes permitting functional protein iterative cycles panning reverse transcription-polymerase chain reaction...
Objective: Cervical cancer classification based on human papillomavirus (HPV) infection status is necessary, as the popularity of HPV vaccination increasing. Hence, this study aimed to explore clinicopathological features, diagnosis, treatment, and prognosis gastric-type endocervical adenocarcinoma (GAS) in west China. Methods: We performed a retrospective analysis follow-up patients with GAS who were hospitalized West China Second University Hospital, tertiary care center China, between...
This study aimed to explore the effect of diffusion tensor imaging (DTI) image registration algorithm in evaluation ventricular remodeling patients with myocardial infarction and therapeutic cross-theoretical model rehabilitation exercise care. The dynamic balance coefficient k was introduced construct DTI k-AD based on variable parameter AD algorithm. Then, it compared demons applied 110 acute infarction. All were divided into 55 cases experimental group (cross-theoretical nursing) control...
：Objective To study thefeature of MIG and IFN-γ obtained from PBMCsstimulated with Mtb specific antigens the potential value in differentialdiagnosis active pulmonary tuberculosis bacterial pneumonia primary lungcancer. Methods 90 patients 31 withbacterial lung cancer were enrolled. IFN-γinsupernatants PBMCs stimulated Mycobacterium tuberculosis-specific wereanalyzed Bender Flowcytomix on flow cytometry. The diagnostic values establishedbased receiver operating characteristic curve analysis....
Objective To compare the effects of Leep knife and microwave on patients with chronic cervicitis.Methods Ninety-six cervicitis were randomly divided into two groups,the control group(n =48 cases) observation cases).The in group treated through microwave,while knife.Tumor necrosis factor-α(TNF-αt) interleukin-6 (IL-6) detected before after treatment.Results The total efficicities 95.8％ 87.5％ group.There was signicicant difference between groups (P ＜ 0.05).The levels TNF-α IL-6 decreased...
Objective: to investigate the causes and treatment of delayed pseudoaneurysm after percutaneous coronary intervention via femoral artery approach. Methods: Make restrospective analysis clinical data 13 patients with in 2036 heart disease. Results: cases were diagnosed which caused severe atherosclerosis artery. Among them, there are 11 successfully repaired by ultrasound guided compression; 1 case was unsuccessful compression but be thrombin injection under guidance; suffered from...