A5101864776- Nanoplatforms for cancer theranostics
- Dental Implant Techniques and Outcomes
- Bone Tissue Engineering Materials
- Graphene and Nanomaterials Applications
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Oral and gingival health research
- Plant Stress Responses and Tolerance
- Advanced Nanomaterials in Catalysis
- Luminescence and Fluorescent Materials
- Extracellular vesicles in disease
- Plant Micronutrient Interactions and Effects
- Machine Learning in Materials Science
- Electrochemical Analysis and Applications
- Hydrogels: synthesis, properties, applications
- Immune cells in cancer
- Mechanical Circulatory Support Devices
- Polymer Surface Interaction Studies
- Plant responses to water stress
- Phagocytosis and Immune Regulation
- Melanoma and MAPK Pathways
- Photodynamic Therapy Research Studies
- Anatomy and Medical Technology
- Electrospun Nanofibers in Biomedical Applications
- Mesenchymal stem cell research
Chongqing Medical University
2020-2025
Stomatological Hospital of Chongqing Medical University
2020-2025
Affiliated Hospital of Southwest Medical University
2023-2024
Sun Yat-sen Memorial Hospital
2024
Sun Yat-sen University
2024
Zhengzhou University
2022
Shenyang Normal University
2014
General Hospital of Jinan Military Command
2000
The regeneration of diabetic bone defects remains challenging as the innate healing process is impaired by glucose fluctuation, reactive oxygen species (ROS), and overexpression proteinases (such matrix metalloproteinases, MMPs). A "diagnostic" therapeutic dual-logic-based hydrogel for therefore developed through design a double-network consisting phenylboronic-acid-crosslinked poly(vinyl alcohol) gelatin colloids. It exhibits logic to interpret pathological cues (glucose ROS, MMPs)...
The regeneration of bone defects in patients with diabetes mellitus (DM) is remarkably impaired by hyperglycemia and over-expressed proinflammatory cytokines, proteinases (such as matrix metalloproteinases, MMPs), etc. In view the fact that exosomes represent a promising nanomaterial, herein, we reported excellent capacity stem cells from apical papilla-derived (SCAP-Exo) to facilitate angiogenesis osteogenesis whether normal or diabetic conditions vitro. Then, bioresponsive polyethylene...
Abstract Currently used wound dressings are ineffective. Hence, there is a need to develop introduce high‐performance medicament with multiple functions including rapid hemostasis and excellent antibacterial activity meet the growing worldwide demand for healing products. Here, inspired by strong adhesion of mussels enzyme‐mimicking nanometallic biomaterials, authors developed an injectable hydrogel overcome limitations current dressings. The synthesized via esterification reaction between...
Abstract Risk of implant failure increases profoundly in patients with pre‐existing conditions (e.g., diabetes). Current therapies adopt a one‐sided focus on the direct antibacterial properties biomaterials and osteogenesis stimulation. However, this study it is demonstrated that “chain armor” structure (Ce‐TA) mainly targets regulation local pathological microenvironment, provides novel solution to scavenge reactive oxygen species (ROS) by simulating superoxide dismutase catalase...
Abstract Existing bone tissue engineering strategies aim to achieve minimize surgical trauma, stabilize the injured area, and establish a dynamic osteogenic microenvironment. The cutting‐edge glue developed in this study satisfies these criteria. Inspired by excellent adhesive properties of mussels, herein, super (L‐DPZ) that integrates poly(vinyl alcohol), L‐dopa amino acid, zeolitic imidazolate framework‐8 characterized catechol–metal coordination is used successfully adhere hard with...
Infected bone defects (IBDs) exhibit impaired healing due to excessive inflammation triggered by pathogen-associated molecular patterns (PAMPs) from bacteria. As a vital factor in orchestrating immune responses, mitochondrial homeostasis maintenance is central blockade. This research developed chameleon-like nanoplatform covering hydroxyapatite nanoparticles with cerium ion coordinated tannic acid supramolecular network (HA@Ce-TA), which adaptively functions regulate based on intra- and...
Photothermal therapy (PTT) demonstrates significant potential in cancer treatment, wound healing, and antibacterial therapy, with its efficacy largely depending on the performance of photothermal agents (PTAs). Metal‐phenolic network (MPN) materials are ideal PTA candidates due to their low cost, good biocompatibility excellent ligand‐to‐metal charge transfer properties. However, not all MPNs exhibit properties, vast chemical space (over 700,000 combinations) complicates screening...
Photothermal therapy (PTT) demonstrates significant potential in cancer treatment, wound healing, and antibacterial therapy, with its efficacy largely depending on the performance of photothermal agents (PTAs). Metal-phenolic network (MPN) materials are ideal PTA candidates due to their low cost, good biocompatibility excellent ligand-to-metal charge transfer properties. However, not all MPNs exhibit properties, vast chemical space (over 700,000 combinations) complicates screening...
Objective As dental implanting becomes an increasing demand among patients with tooth loss, efficient and effective training for students is to be necessary. In this case, we anticipate the possible application of virtual reality (VR) technology pre-clinical implantation (PCIT) in order improve students’ learning efficiency effectiveness. Methods The study divided 20 subjects into two groups on average—VR based PCIT (experimental group) traditional (control completion background survey (BS)...
Background: Near-infrared cyanine dyes have high sensitivity and spatial resolution imaging capabilities, but they also unavoidable drawbacks such as photobleaching, low water solubility, fluorescence quenching, toxic side effects. As an effective biologic drug carrier, albumin combines with to form albumin@dye nanoparticles. These nanoparticles can alleviate the aforementioned issues are widely used in tumor photothermal therapy. Methods: Herein, a newly synthesized near-infrared dye IR-817...
To develop an in vivo model to simulate the complex internal environment of diabetic peri-implantitis (T2DM-PI) for a better understanding type 2 patients.Maxillary first molars were extracted Sprague-Dawley (SD) rats, and customized cone-shaped titanium implants installed extraction sites. Thereafter, uncovered abutments screwed into implants. A high-fat diet low-dose injection streptozotocin utilized induce T2DM. Finally, LPS was locally injected implant sulcus peri-implantitis.In present...
Renal fibrosis serves as the shared pathway in chronic kidney disease (CKD) progression towards end-stage renal (ESRD). Endothelial-mesenchymal transition (EndMT) is a vital mechanism leading to generation of myofibroblasts, thereby contributing advancement fibrogenesis. Baculoviral IAP Repeat Containing 3(Birc3) was identified crucial inhibitor cell death and significant mediator inflammatory signaling immunity. However, its involvement development interstitial via EndMT still needs be...
Adv. Funct. Mater. 2021, 31, 2101611 DOI: 10.1002/adfm.202101611 In the version of this Research Article originally published, UV–vis absorption spectra NBT (Figure 2d) and one picture H&E staining heart S17) were incorrect. The corrected figures are shown below. Corrected figure original Figure 2d. for S17. These errors do not affect conclusions report. authors apologize any inconvenience caused.