A5100388467- RNA modifications and cancer
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Neurological Disease Mechanisms and Treatments
- Gastric Cancer Management and Outcomes
- Anesthesia and Pain Management
- Pancreatic and Hepatic Oncology Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Enhanced Recovery After Surgery
- Cancer-related gene regulation
- Pancreatitis Pathology and Treatment
- Surgical site infection prevention
- Abdominal vascular conditions and treatments
- Pelvic and Acetabular Injuries
- Spine and Intervertebral Disc Pathology
- Nausea and vomiting management
- Neurological Disorders and Treatments
- Surgical Sutures and Adhesives
- Tracheal and airway disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Cervical and Thoracic Myelopathy
- Knee injuries and reconstruction techniques
- Organ Transplantation Techniques and Outcomes
- Stroke Rehabilitation and Recovery
Shaoxing People's Hospital
2022-2024
Qingdao University
2024
University of Science and Technology of China
2023-2024
Anhui Provincial Hospital
2023-2024
Shenzhen Children's Hospital
2024
University of Houston
2018-2024
Shanghai Normal University
2024
Zhengzhou University
2024
Hong Kong Polytechnic University
2024
Jiangsu Normal University
2018-2023
Abstract Existing bone tissue engineering strategies aim to achieve minimize surgical trauma, stabilize the injured area, and establish a dynamic osteogenic microenvironment. The cutting‐edge glue developed in this study satisfies these criteria. Inspired by excellent adhesive properties of mussels, herein, super (L‐DPZ) that integrates poly(vinyl alcohol), L‐dopa amino acid, zeolitic imidazolate framework‐8 characterized catechol–metal coordination is used successfully adhere hard with...
Abstract Background A previously trained deep learning-based smartphone app provides an artificial intelligence solution to help diagnose biliary atresia from sonographic gallbladder images, but it might be impractical launch in real clinical settings. This study aimed redevelop a new model using original images and their derived photos then test the model’s performance assisting radiologists with different experiences detect real-world mimic Methods was first retrospectively 3659 51,226...
Background/Aims: Alpha-lipoic acid (α-LA) has been demonstrated to be protective against cerebral ischemia injury. Herein, we investigate the neuroprotective effect and underlying mechanisms of α-LA. Methods: In vivo study, α-LA was administered intravenously upon reperfusion transient middle artery occlusion. Garcia score used evaluate neurologic recovery. Infarct volume examined by TTC staining, oxidative damage evaluated ELISA assay. an in vitro neurons were pretreated with at different...
Purpose: We designed this study to investigate the effect of intravenous use penehyclidine on postoperative nausea and vomiting (PONV) after gynecological laparoscopic surgery. Patients Methods: Ninety-two Women (Aged ≥ 18) Scheduled for Elective Gynecologic Laparoscopy Were Enrolled in Current Study. Equally Randomized Assigned Into Penehyclidine group (PHC group: received a bolus 10 μg/kg during induction anesthesia, then followed by continuous infusion at fixed rate 2.0 mL/h analgesia...
Fibromyalgia syndrome (FMS) is a recurrent pain condition that can be challenging to treat. Transcranial direct current stimulation (tDCS) has become promising non-invasive therapeutic option in alleviating FMS pain, but the mechanisms underlying its effectiveness are not yet fully understood. In this article, we discuss most research investigating analgesic effects of tDCS on and potential mechanisms. TDCS may exert by influencing neuronal activity brain, altering cortical excitability,...
To investigate the effect of intravenous infusion lidocaine compared with ultrasound-guided transverse abdominal plane (TAP) block on quality postoperative recovery and analgesic in patients undergoing bariatric surgery.
Background/Aims: Ischemic stroke results in increased cerebral infarction, neurological deficits and neuroinflammation. The underlying mechanisms involving the anti-inflammatory neuroprotective properties of α-Lipoic acid (α-LA) remain poorly understood. Herein, we investigated potential role α-LA a middle artery occlusion (MCAO) rat model an vitro lipopolysaccharide (LPS)-induced microglia inflammation model. Methods: In vivo study, infarct volume was examined by TTC staining Garcia score...
J Oral Pathol Med (2010) 39: 548–551 Aims: To investigate the relationship between paxillin expression and clinicopathological features metastasis in salivary adenoid cystic carcinoma (SACC). Methods: A total of 47 SACC were assessed histochemically for expression. Paxillin immunoreactivity was compared with histological type, clinical stage distant metastasis. Results: identified 57.45% as cytoplasmic staining correlated (P < 0.05), but not type. Conclusions: Our observations indicate that...
Laminoplasty has been used in recent years as an alternative approach to laminectomy for preventing spinal deformity after resection of intramedullary cord tumors (IMSCTs). However, controversies exist with regard its real role maintaining postoperative alignment. The purpose this study was examine the incidence progressive patients who underwent laminoplasty IMSCT and identify risk factors deformity.
Glioblastoma multiforme (GBM) is a highly aggressive primary brain tumor characterized by poor prognosis and lack of effective treatments. In recent years, peptide vaccines that use sequences based on tumor-specific or tumor-associated antigens to activate immune responses against cells have emerged as new therapeutic strategy. this study, we developed novel polypeptide vaccine targeting the antigen Fibrinogen-Like Protein 2 (FGL2), whose dominant epitope was tandemly linked C-terminus...
Abstract The study aimed to investigate whether S100A9 gene silencing mediating the IL ‐17 pathway affected release of pro‐inflammatory cytokines in acute pancreatitis ( AP ). Kunming mice were assigned normal, , + negative control NC ), sh RNA IgG and anti groups. ELISA was applied measure expressions AMY LDH CRP TNF ‐α, ‐6 ‐8. cells distributed into control, blank, 1 2 MTT assay, flow cytometry, RT ‐ qPCR Western blotting used evaluate cell proliferation, cycle apoptosis, S100A9, TLR 4,...
Background Sporadic fundic gland polyps (FGPs) are common gastric polyps. Some studies reported that FGPs dramatically increased due to proton pump inhibitors (PPIs) use and a decreased prevalence of Helicobacter pylori ( H. ) infection in Western countries. However, data still controversial. This study aimed identify the relationships between these two factors China. Methods Consecutive patients with detected were retrospectively analyzed. Data including patients’ age, sex, symptoms,...
PER2, a circadian clock gene, is associated with mammary gland development and lipid synthesis in rodents, partly via regulating peroxisome proliferator-activated receptor gamma (PPARG). Whether such type of molecular link existed bovines was unclear. We hypothesized that PER2 metabolism regulated cell cycles apoptosis bovine epithelial cells (BMECs). To test this hypothesis, BMECs isolated from three mid-lactation (average 110 d postpartum) cows were used. The transient transfection small...
We aim to compare the efficiency of erector spinae plane block (ESPB) with transversus abdominis (TAPB) in patients undergoing laparotomic radical hysterectomy because only a few studies are reported exploring this matter.In randomized controlled trail, 154 eligible were randomly allocated into ESPB group [ESPB + patient-controlled intravenous analgesia (PCIA)] and TAPB (TAPB PCIA) at 1:1 ratio. The primary outcome was visual analog scale (VAS) score rest state 12 h.We found that associated...
As a common complication of sepsis, sepsis-associated encephalopathy (SAE) is characterized by diffuse brain dysfunction and neurological damage closely associated with long-term cognitive dysfunction. The dysregulated host response triggered neurotoxicity microglia an important cause in SAE. Resveratrol glycoside has anti-inflammatory antioxidant effects. However, there no evidence whether resveratrol could alleviate SAE.LPS administration was used to induce SAE mice. Step-down test (SDT)...
Abstract Background Vagus nerve stimulation (VNS) is an effective treatment for patients with refractory epilepsy, yet varied predictive factors and heterogeneous long-term outcomes. Adjustment of VNS parameters critical obtaining favorable efficacy. In this study, we aimed to investigate the outcomes possible in epilepsy. Methods Eighty-six (59 males 27 females) who underwent implantation epilepsy between May 2016 2017 at five Epilepsy Centers were enrolled. The clinical data, including...