- Atrial Fibrillation Management and Outcomes
- Heart Rate Variability and Autonomic Control
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Cardiac Arrhythmias and Treatments
- Cardiovascular Function and Risk Factors
- Cardiovascular Disease and Adiposity
- Coronary Interventions and Diagnostics
- Obstructive Sleep Apnea Research
- Cardiac electrophysiology and arrhythmias
- Venous Thromboembolism Diagnosis and Management
- Adipokines, Inflammation, and Metabolic Diseases
- Inflammatory Biomarkers in Disease Prognosis
- Complex Systems and Time Series Analysis
- Non-Invasive Vital Sign Monitoring
- Cardiovascular Health and Risk Factors
- Cardiac Health and Mental Health
- Cardiac Valve Diseases and Treatments
- Blood Pressure and Hypertension Studies
- Cardiovascular Effects of Exercise
- ECG Monitoring and Analysis
- Chaos control and synchronization
- Cardiac, Anesthesia and Surgical Outcomes
- Lipoproteins and Cardiovascular Health
- Traditional Chinese Medicine Studies
First Affiliated Hospital of Bengbu Medical College
2023-2025
Shanghai Jiao Tong University
2014-2025
Shanghai First People's Hospital
2024-2025
Ningde Normal University
2024-2025
Fujian Medical University
2024-2025
Hangzhou First People's Hospital
2025
Second Affiliated Hospital of Nanchang University
2024
Nanchang University
2024
Wuhan University
2012-2024
Chinese Center For Disease Control and Prevention
2010-2024
Abstract Background The triglyceride glucose (TyG) index is a well-established biomarker for insulin resistance (IR) that shows correlation with poor outcomes in patients coronary artery disease. We aimed to integrate the TyG clinical data prediction nomogram long-term prognosis of new onset ST-elevation myocardial infarction (STEMI) following primary percutaneous intervention (PCI) . Methods This retrospective study included new-onset STEMI admitted at two heart centers emergency PCI from...
Vagal responses and phrenic activation are commonly observed during pulsed field ablation (PFA). However, whether the vagal activations nerve damage or a neurological stress response due to electrical stimulation is unclear.The purpose of this study was evaluate effect PFA system for performing pulmonary vein isolation on autonomic nervous system.Patients with paroxysmal atrial fibrillation (AF) who underwent between August 2021 November were included. Nerve injury biomarkers heart rate...
Biomarker of insulin resistance, namely triglyceride-glucose index, is potentially useful in identifying critically ill patients at high risk hospital death. However, the TyG index might have variations over time during ICU stay. Hence, purpose current research was to verify associations between dynamic change stay and all-cause mortality.The present retrospective cohort study conducted using Medical Information Mart for Intensive Care IV 2.0 (MIMIC-IV) critical care dataset, which included...
Obesity and imbalance in lipid homeostasis contribute greatly to heart failure with preserved ejection fraction (HFpEF), the dominant form of failure. Few effective therapies exist control metabolic alterations homeostasis.
Obstructive sleep apnea syndrome (OSAS), a prevalent condition, often coexists with intricate metabolic issues and is frequently associated negative cardiovascular outcomes. We developed longitudinal prediction model integrating multimodal data for risk stratification of patients an initial diagnosis OSAS.
Objective To investigate the association between atherogenic index of plasma (AIP) and risk incident kidney stones.
Background Digital education for outpatient patients with atrial fibrillation (AF) has gradually increased. However, research on digital undergoing catheter ablation (AFCA) is limited. Objective This study aimed to develop a novel animation-based multistage system and evaluate its quality-of-life benefits AFCA. Methods randomized controlled clinical trial included 208 AF who underwent in the Department of Cardiology at Renmin Hospital Wuhan University between January 2022 August 2023. The...
This study aimed to investigate the risk factors for intensive care unit mortality in patients with intracerebral hemorrhage after surgery and construct a clinical nomogram. The data this retrospective analysis were acquired from Medical Information Mart Intensive Care IV (MIMIC-IV) database, controls randomly divided into training validation subsets ratio of 7:3. primary endpoint was all-cause ICU mortality. prediction model developed, nomogram generated based on findings logistic...
Background Gla-rich protein (GRP) and interleukin-1β (IL-1β) are recognized as reliable biomarkers for evaluating inflammation effective predictors of cardiovascular disease. However, the relationship between GRP, IL-1β, coronary artery calcification (CAC) in patients with suspected disease (CAD) remains unclear. Therefore, we investigated association these inflammatory (GRP IL-1β) CAC CAD. Methods This prospective study included CAD who underwent computed tomography angiography (CTA)....
To determine the role of MYL4 regulation lysosomal function and its disturbance in fibrotic atrial cardiomyopathy. We have previously demonstrated that atrial-specific essential light chain protein is required for contractile, electrical, structural integrity. mutation/dysfunction leads to fibrosis, standstill, dysrhythmia. However, underlying pathogenic mechanisms remain unclear. Rats subjected knock-in a mutant (p.E11K) developed Proteome analysis single-cell RNA sequencing indicate...
Background The advantages of multimodal digitally transformed mobile health management for patients diagnosed with mild to moderate hypertension are not yet established. Objective We aim evaluate the therapeutic benefits a novel WeChat-based digital transforming model in blood pressure (BP) management. Methods This randomized controlled clinical trial included 175 individuals new-onset who were admitted our center between September and October 2022. randomly assigned either intervention...
Circular ribonucleic acids (RNAs) (circRNAs) are formed by covalently linking the downstream splice donor and upstream acceptor. One of most important functions circRNAs is mainly exerted through binding RNA-binding proteins (RBPs). However, there no efficient algorithm for identifying genome-wide circRNA-RBP interactions. Here, we developed a unique algorithm, circRIP, interactions from RNA immunoprecipitation sequencing (RIP-Seq) data. A simulation test demonstrated sensitivity specificity...
: Hypertension is an important contributing factor to atherosclerotic cardiovascular disease (ASCVD), and multiple risk factors, many of which are implicated in metabolic disorders, contribute the cause hypertension. Despite promise multimodal data-driven prediction model, no such model was available predict ASCVD Chinese individuals with new-onset hypertension history ASCVD.
Background: Acute myocardial infarction (AMI) is mainly caused by a mismatch of blood oxygen supply and demand in the myocardium. However, several studies have suggested that excessively high or low arterial tension could deleterious effects on prognosis AMI patients. Therefore, relationship between oxygenation clinical outcomes among patients unclear, be nonlinear. In critical care setting, level commonly measured continuously using pulse oximetry-derived saturation (SpO2). The present...
To investigate the effect of intravenous infusion lidocaine compared with ultrasound-guided transverse abdominal plane (TAP) block on quality postoperative recovery and analgesic in patients undergoing bariatric surgery.