A5101797915- Liver Disease Diagnosis and Treatment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Dialysis and Renal Disease Management
- Respiratory Support and Mechanisms
- Central Venous Catheters and Hemodialysis
- Asthma and respiratory diseases
- Antifungal resistance and susceptibility
- Liver Diseases and Immunity
- Vascular Procedures and Complications
- Liver Disease and Transplantation
- Adipokines, Inflammation, and Metabolic Diseases
- Synthesis and Biological Evaluation
- Diet, Metabolism, and Disease
- COVID-19 Pandemic Impacts
- Plant chemical constituents analysis
- Regional Development and Management Studies
- Intraocular Surgery and Lenses
- Retinal and Optic Conditions
- Pancreatitis Pathology and Treatment
- Business and Economic Development
- Phytochemicals and Medicinal Plants
- Ocular Infections and Treatments
- Economic Analysis and Policy
- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
Datta Meghe Institute of Medical Sciences
2021-2025
University of South Alabama
2019-2024
USA Mitchell Cancer Institute
2021-2024
University of California, San Diego
2018-2024
King George's Medical University
2015-2024
Michigan State University
2024
University of Kashmir
2021
University of Lucknow
2020
Adesh University
2020
Sound Shore Medical Center
2018-2019
Patients with non-alcoholic fatty liver disease (NAFLD) ≥stage 2 fibrosis are at increased risk for liver-related mortality and candidates pharmacological therapies treatment of NAFLD. The aim this prospective cohort study is to examine the diagnostic accuracy MR elastography (MRE) combined fibrosis-4 (FIB-4) in diagnosing (candidates therapies).This a cross-sectional analysis (University California San Diego (UCSD)-NAFLD) including 238 consecutive patients contemporaneous MRE biopsy-proven...
Summary Background The fasting‐state serum bile acid profile in nonalcoholic fatty liver disease (NAFLD) has been reported to differ when steatohepatitis is compared liver. However, there are few data comparing changes NAFLD vs non‐NAFLD, or whether the differs according degree of fibrosis. Aim To examine across entire spectrum NAFLD. Methods We performed a cross‐sectional analysis two complementary cohorts: Twin and Family cohort 156 participants, biopsy‐proven‐NAFLD participants with...
There are limited prospective data among overweight and obese individuals on the prevalence of advanced fibrosis, cirrhosis using MRI-based methods in USA. The aim this study was to fill that gap knowledge by prospectively determining steatotic liver disease (SLD) its subcategories, fibrosis residing
The current diagnosis of metabolic dysfunction-associated steatotic liver disease (MASLD) and its severe form, steatohepatitis (MASH), is suboptimal. Here, we recruited 700 individuals, including 184 from Hong Kong as a discovery cohort 516 San Diego, Wenzhou, three validation cohorts. A panel 3 parameters (C-X-C motif chemokine ligand 10 [CXCL10], cytokeratin 18 fragments M30 [CK-18], adjusted body mass index [BMI]) was formulated (termed N3-MASH), which discriminated patients with MASLD...
Cross-sectional studies have shown that magnetic resonance elastography (MRE) is accurate in the noninvasive detection of advanced fibrosis nonalcoholic fatty liver disease (NAFLD). However, there are limited data on longitudinal association between an increase stiffness MRE and progression NAFLD. Therefore, using a well-characterized prospective cohort patients with biopsy-proven NAFLD, we aimed to examine 15% NAFLD.This study included 102 (62.7% women) NAFLD who underwent contemporaneous...
Chronic obstructive pulmonary disease (COPD) is a common respiratory condition involving the airways and characterized by airflow limitation. Gaseous noxious particles play an important role in this process. Antioxidants are substances that may protect cells from damage caused unstable molecules known as free radicals. The increased oxidative stress patients with COPD result of burden inhaled oxidants, well amounts reactive oxygen species (ROS) generated various inflammatory, immune...
CXCR1 and CXCR2 are receptors for CXCL-8 differentially expressed on melanoma endothelial cells. In this study, we determined the functional role of these in progression. We stably knock-down expression and/or A375-SM (SM; high metastatic) human cells by short-hairpin RNA transfection. Cell proliferation, migration, invasion, ERK phosphorlyation cytoskeletal rearrangements were carried out vitro. vivo growth was evaluated using murine subcutaneous xenograft model. Our data demonstrate that...
Treatment without catheter replacement (catheter salvage) has been described for bacteremia associated with tunneled venous catheters in hemodialysis patients, but few data are available on which to base an estimation of the likelihood treatment success.In a prospective cohort study, all cases catheter-associated that occurred large dialysis center were identified during 12-mo period. Catheter salvage was attempted according standard protocol favorable early response antibiotic therapy seen,...
Aramchol, an oral stearoyl‐coenzyme‐A‐desaturase‐1 inhibitor, has been shown to reduce hepatic fat content in patients with primary nonalcoholic fatty liver disease (NAFLD); however, its effect human immunodeficiency virus (HIV)–associated NAFLD is unknown. The aramchol for HIV‐associated and lipodystrophy (ARRIVE) trial was a double‐blind, randomized, investigator‐initiated, placebo‐controlled test the efficacy of 12 weeks treatment versus placebo NAFLD. Fifty NAFLD, defined by magnetic...
A BSTRACT Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a significant concern among cancer patients undergoing treatment with neurotoxic drugs, affecting their quality of life. This study evaluates the efficacy Epsom salt foot baths in preventing or delaying CIPN onset asymptomatic cases and alleviating symptoms symptomatic cases. Methods: randomized clinical trial was conducted on 104 patients, divided equally into groups. Each group further subdivided experimental...
Vascular access for haemodialysis is achieved by tunnelled central venous catheter (CVC) in at least 23% of prevalent patients the UK, Canada and USA. Use CVCs associated with an increased incidence stenosis that can progressively limit future vascular routes. Lack conventional routes mandates use alternative strategies such as translumbar approach.We retrospectively analysed our centre requiring inferior vena caval (TesioCath) period 1999-2008. Written electronic records capturing dialysis...
Aspergillus fumigatus is the common cause of allergic broncho-pulmonary aspergillosis (ABPA) and most allergens have been described from its secreted fraction. In present investigation, germinating conidial cytosolic proteins A. were extracted a 16 h culture. The proteome this fraction was developed, immuno-blots generated using pooled ABPA patients' sera. Well separated Immunoglobulin-E (IgE) Immunoglobulin-G (IgG) reactive spots picked corresponding 2DE gels subjected to mass spectrometric...
Setting Our study was conducted at a tertiary care center for respiratory illnesses (Viswanathan Chest Hospital, Vallabhbhai Patel Institute (VPCI), University of Delhi, India). Patients were enrolled in the from outpatient clinic. Objective To assess effects pulmonary rehabilitation (PR) patients with chronic lung impairment previously treated tuberculosis (CLIPTB), on exercise capacity (six-minute walk distance), function tests, quality life and markers systemic inflammation. Design...
The incidence of subdural haematoma (SDH) is high in haemodialysis (HD), with data suggesting an increasing over time. prognosis remains poor 40% mortality at 30 days. extent this problem non-US populations has not been described the literature.We conducted a retrospective, single-centre UK study non-traumatic SDH patients established on maintenance HD between 1 January 2002 and June 2009.The prevalence was 0.4% our centre overall annual 189 per 100 000 patients. associated increased patient...