Hong Phuong Nguyen

ORCID: 0000-0002-6088-9548
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About
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Research Areas
  • Mosquito-borne diseases and control
  • Spaceflight effects on biology
  • Malaria Research and Control
  • Protein Degradation and Inhibitors
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Obesity, Physical Activity, Diet
  • Histone Deacetylase Inhibitors Research
  • Reproductive Physiology in Livestock
  • Immune Response and Inflammation
  • Optical Imaging and Spectroscopy Techniques
  • Advanced Thermodynamics and Statistical Mechanics
  • School Health and Nursing Education
  • Fuel Cells and Related Materials
  • Topic Modeling
  • High Altitude and Hypoxia
  • Membrane Separation Technologies
  • Autophagy in Disease and Therapy
  • Mitochondrial Function and Pathology
  • Membrane Separation and Gas Transport
  • Algorithms and Data Compression
  • Reproductive System and Pregnancy
  • Medical and Biological Ozone Research
  • Muscle and Compartmental Disorders
  • Cardiovascular Health and Risk Factors
  • Photoacoustic and Ultrasonic Imaging

Indiana University School of Medicine
2023

Indiana University – Purdue University Indianapolis
2023

Hanoi University of Science and Technology
2023

Inha University
2021-2022

Duy Tan University
2021

International Food Policy Research Institute
2021

Monash University
2013

Monash Institute of Medical Research
2013

Hydro-Québec
2004

A Role for IFN-ɛ Type I interferons (IFNs) are critical cytokines involved in host defense against pathogens, particularly viruses. is an IFN-like gene encoded within the type IFN locus mice and humans whose function has not been characterized. Fung et al. (p. 1088 ) created with a genetic deletion Ifn -ɛ found that, like other IFNs, signals through IFN-α receptors 1 2. However, unlike these cytokines, which primarily expressed by immune cells induced upon cell triggering, was exclusively...

10.1126/science.1233321 article EN Science 2013-02-28

Multiple myeloma is a deadly cancer that complex and multifactorial disease. In the present study, 12 belinostat derivatives (four resynthesized eight new), HDAC inhibitors, were via either Knoevenagel condensation, or Wittig reaction, Heck reaction. Then an evaluation of antiproliferative activities against cells MOPC-315 was carried out. Amongst them, compound 7f most bioactive with IC50 0.090 ± 0.016 μM, being 3.5-fold more potent than reference (IC50 = 0.318 0.049 μM). Furthermore, we...

10.1039/d2ra01969h article EN cc-by-nc RSC Advances 2022-01-01

The World Health Organization has designated Zika virus (ZIKV) as a dangerous, mosquito-borne flaviviral pathogen that was recently found to be responsible for dramatically increased number of microcephaly cases and other congenital abnormalities in fetuses newborns. There is neither vaccine prevent nor drug treat ZIKA infections, at the present time. Berberine (BBR) promising approved by FDA against dengue virus, BBR derivatives are great interest antiviral development. In this study, we...

10.1155/2021/5567111 article EN cc-by Journal of Chemistry 2021-04-18

This work presented the design and fabrication of a blood vessel breast tumor detection device (BKA-06) based on optical energy spectroscopy. The BKA-06 uses red-to-near-infrared light-emitting diodes that allow physicians or to visualize vessels surface structures such as tumors with naked eye. consists built-in current control circuit have appropriate brightness (maximum illuminance 98,592 lux) for examination superficial deep under skin, scan time 3-5 min. can facilely observe each layer...

10.3390/bioengineering10111272 article EN cc-by Bioengineering 2023-11-01

The Zika virus (ZIKV) is believed to cause birth defects, and no anti-ZIKV drugs have been approved by medical organizations date. Starting from antimicrobial lead compounds with a pyrazolo[3,4-d]pyridazine-7-one scaffold, we synthesized 16 derivatives screened their ability interfere ZIKV infection utilizing cell-based phenotypic assay. Of these, five showed significant inhibition of selective index value greater than 4.6. In particular, compound 9b the best activity selectivity 22.4...

10.1021/acsomega.3c06612 article EN cc-by-nc-nd ACS Omega 2023-12-14

Background Adolescence is a vulnerable period for many lifestyle risk behaviors. In this study, we aimed to 1) examine clustering pattern of behaviors; 2) investigate roles the school health promotion programs on among adolescents in Vietnam. Methods We analyzed data 7,541 aged 13-17 years from 2019 nationally representative Global School-based Student Health Survey, conducted 20 provinces and cities applied latent class analysis identify groups used Bayesian 2-level logistic regressions...

10.1101/2021.03.26.21254389 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2021-03-26

This work presented the design and fabrication of blood vessel breast tumor detection device (BKA-06) based on optical energy spectroscopy. The BKA-06 uses red-to-near-infrared light-emitting diodes that allow physicians or to visualize vessels surface structures such as tumors with naked eye. consisted built-in current control circuit have appropriate brightness (maximum illuminance 98592 lux) for examination superficial deep under skin, a scan time 3-5 minutes. could facilely observe each...

10.20944/preprints202308.1105.v1 preprint EN 2023-08-15
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