Rajinder Singh

ORCID: 0000-0002-6174-4973
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About
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Research Areas
  • Carcinogens and Genotoxicity Assessment
  • DNA Repair Mechanisms
  • Forensic and Genetic Research
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Cultural Heritage Materials Analysis
  • Spectroscopy and Chemometric Analyses
  • Forensic Fingerprint Detection Methods
  • Identification and Quantification in Food
  • DNA and Nucleic Acid Chemistry
  • Metal complexes synthesis and properties
  • Organometallic Compounds Synthesis and Characterization
  • Epigenetics and DNA Methylation
  • Plant Genetic and Mutation Studies
  • Metabolomics and Mass Spectrometry Studies
  • Air Quality and Health Impacts
  • Folate and B Vitamins Research
  • Glutathione Transferases and Polymorphisms
  • Agricultural Practices and Plant Genetics
  • Silymarin and Mushroom Poisoning
  • Cytomegalovirus and herpesvirus research
  • Synthesis and biological activity
  • Currency Recognition and Detection
  • Plant Pathogens and Fungal Diseases
  • Plant Pathogens and Resistance
  • Crop Yield and Soil Fertility

Punjabi University
2015-2025

Manchester University
2024

University Foundation
2024

Government of Uttar Pradesh
2023-2024

University of Leicester
2011-2022

Leicester Royal Infirmary
2009-2021

Institute of Technology Management
2019

R.V. College of Engineering
2017

Punjab Agricultural University
2016

Guru Nanak Dev University
2014

Studies in vitro and animal models of colorectal hepatocellular cancers suggest that curcumin is an effective chemopreventive agent. In this pilot trial, we investigated whether oral administration results concentrations the agent normal malignant human liver tissue, which are sufficient to elicit pharmacological activity. total, 12 patients with hepatic metastases from cancer received 450–3600 mg daily, for 1 week prior surgery. Levels its metabolites were measured by HPLC portal peripheral...

10.1038/sj.bjc.6601623 article EN cc-by-nc-sa British Journal of Cancer 2004-03-01

The antibacterial activity of peppermint oil and different extracts Mentha piperita against some Gram-positive Gram-negative bacterial strains was evaluated in the present research work by agar well diffusion method. It found that distilled concentrations essential inhibited growth microorganisms results were comparable with those antibiotic gentamycin. Essential oils showed a wider spectrum but less strong inhibition as compared to investigated commercial antibiotic. Minimum inhibitory...

10.1016/j.arabjc.2011.01.019 article EN cc-by-nc-nd Arabian Journal of Chemistry 2011-01-23

Aims: Urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) is a widely used biomarker of oxidative stress. However, variability between chromatographic and ELISA methods hampers interpretation data, this may increase should urine composition differ individuals, leading to assay interference. Furthermore, optimal sampling conditions are not well defined. We performed inter-laboratory comparisons 8-oxodG measurement mass spectrometric-, electrochemical- ELISA-based methods, using common...

10.1089/ars.2012.4714 article EN Antioxidants and Redox Signaling 2012-12-02

In order to achieve a better outcome for pancreatic cancer patients, reliable biomarkers are required which allow improved diagnosis. These may emanate from more detailed molecular understanding of the aggressive nature this disease. Having previously reported that Notch3 activation appeared be associated with disease, we have now examined components pathway (Notch1, Notch3, Notch4, HES-1, HEY-1) in detail resectable (n = 42) and non-resectable 50) tumours compared uninvolved pancreas. All...

10.1371/journal.pone.0051119 article EN cc-by PLoS ONE 2012-12-04

The most important task in a criminal investigation is to detect and identify the recovered biological stains beyond reasonable scientific doubt preserve sample for further DNA analysis. In light of this fact, many presumptive confirmatory tests are routinely employed forensic laboratories determine type body fluid. However, currently used techniques specific one fluid hence it cannot be utilized differentiate multiple fluids. Moreover, these consume samples due process, thus becomes great...

10.1177/00258024211010926 article EN Medicine Science and the Law 2021-04-30

Research into the metabolism of non-essential amino acid (NEAA) proline in cancer has gained traction recent years. The last step biosynthesis pathway is catalyzed by pyrroline-5-carboxylate reductase (PYCR) enzymes. There are three PYCR enzymes: mitochondrial PYCR1 and 2 cytosolic PYCR3 encoded separate genes. expression gene increased numerous malignancies correlates with poor prognosis. sustains cells’ proliferation survival several mechanisms have been implicated to explain its oncogenic...

10.1371/journal.pone.0262364 article EN cc-by PLoS ONE 2022-02-07
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