A5014867525- Radiation Therapy and Dosimetry
- Nuclear Physics and Applications
- Radiation Detection and Scintillator Technologies
- Particle Detector Development and Performance
- Gamma-ray bursts and supernovae
- Advanced X-ray and CT Imaging
- Medical Imaging Techniques and Applications
- Advanced Radiotherapy Techniques
- Photocathodes and Microchannel Plates
- Atomic and Subatomic Physics Research
- Particle Accelerators and Free-Electron Lasers
- Nuclear physics research studies
- Radiation Effects in Electronics
- Cryospheric studies and observations
- CCD and CMOS Imaging Sensors
Heidelberg University
2014-2020
Ludwig-Maximilians-Universität München
2014-2020
University Hospital Heidelberg
2014-2020
University College Dublin
2016
LMU Klinikum
2016
Institute of Metallurgy and Materials Science
2016
Polish Academy of Sciences
2016
Politecnico di Milano
2016
This paper describes a time-marking system that enables measurement of the in-plane (horizontal) polarization 0.97-GeV/c deuteron beam circulating in Cooler Synchrotron (COSY) at Forschungszentrum J\"ulich. The clock time each polarimeter event is used to unfold 120-kHz spin precession and assign events bins according direction horizontal polarization. After accumulation for one or more seconds, down-up scattering asymmetry can be calculated matched sinusoidal function whose magnitude...
Ion beam therapy offers the possibility of a highly conformal tumor-dose distribution; however, this technique is extremely sensitive to inaccuracies in treatment procedures. Ambiguities conversion Hounsfield units planning x-ray CT relative stopping power (RSP) can cause uncertainties estimated ion range up several millimeters. (iCT) represents favorable solution allowing directly assess RSP. In simulation study we investigate performance integration-mode configuration for carbon iCT,...
The dosimetric advantages of ion therapy come at the cost an increased sensitivity to range inaccuracies in treatment planning and delivery stages. This prompts development imaging techniques capable accurate assessment relative stopping power (RSP). We investigate carbon-ion based on a prototype integration-mode detector working as telescope. Experiments were conducted Heidelberg Ion-Beam Therapy Center with active pencil beam scanning. aim this article is experimentally operate system...
ICTR-PHE
In particle therapy, the x-ray based treatment planning converting photon attenuation values to relative stopping power ratio (RSP) introduces clinically relevant range uncertainties. Recently, novel imaging technologies using transmission ion beams have been investigated directly assess water equivalent thickness (WET) of tissue, showing improved accuracy in RSP reconstruction, while potentially reducing dose. Due their greater availability, protons mostly used for imaging. To this end,...
The sensitivity of ion therapy to inaccuracies in treatment planning and delivery procedures demands the development imaging techniques capable accurate assessment Relative (to water) Stopping Power (RSP). investigated tomographic carbon CT (iCT) setup consists a prototype integration-mode detector working as range telescope using active scanning beam delivery. Extensive Monte Carlo simulations FLUKA code were performed compared experimental data. influence acquisition parameters was...
External beam radiotherapy techniques have the common aim to maximize radiation dose target while sparing surrounding healthy tissues. The inverted and finite depth-dose profile of ion beams (Bragg peak) allows for precise delivery conformai distribution. Furthermore, increased radiobiological effectiveness ions enhances capability battle radioresistant tumors. Ion therapy requires a determination range, which is particularly sensitive range uncertainties. Therefore, novel imaging are...
Purpose: Ion beams exhibit a finite range and an inverted depth‐dose profile, the Bragg peak. These favorable properties allow superior tumordose conformality, but introduce sensitivity to uncertainties. Hence, imaging techniques play increasingly important role support treatment planning in‐vivo monitoring of actual ion beam treatment. Methods: This work presents experimental investigations carried out address feasibility transmission at Heidelberg Therapy center using active raster...