A5103158189- Renal Diseases and Glomerulopathies
- Pediatric Urology and Nephrology Studies
- Chronic Kidney Disease and Diabetes
- Urinary Tract Infections Management
- Urological Disorders and Treatments
- Ion Transport and Channel Regulation
- Yersinia bacterium, plague, ectoparasites research
- Renin-Angiotensin System Studies
- Plant-based Medicinal Research
- Urinary Bladder and Prostate Research
- Viral Infections and Vectors
- Vasculitis and related conditions
- Respiratory viral infections research
- Kidney Stones and Urolithiasis Treatments
- Hormonal Regulation and Hypertension
- Vibrio bacteria research studies
- Complement system in diseases
- Electrolyte and hormonal disorders
- Drug-Induced Adverse Reactions
- Urticaria and Related Conditions
- Leptospirosis research and findings
- Nephrotoxicity and Medicinal Plants
- COVID-19 Impact on Reproduction
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Lymphatic Disorders and Treatments
Inje University Sanggye Paik Hospital
2010-2024
Inje University
2004-2012
Wonkwang University
2010
Seoul National University Children's Hospital
1996
Samsung Medical Center
1996
Seoul National University
1993-1996
To investigate the epidemiology, clinical manifestations, investigations and management, prognosis of patients with Henoch-Schonlein purpura (HSP).We performed a retrospective review 212 HSP under age 18 years who were admitted to Inje University Sanggye Paik Hospital between 2004 2015.The mean was 6.93 years, ratio boys girls 1.23:1. occurred most frequently in winter (33.0%) least summer (11.3%). Palpable spots found 208 (98.1%), gastrointestinal (GI) joint symptoms observed 159 (75.0%)...
Purpose Recent studies have established the association between hypotonic fluids administration and hospital-acquired hyponatremia in children. The present paper investigated pattern of current practice intravenous fluid prescription among Korean pediatric residents, to underscore need for updated education. Methods A survey-based analysis was carried out. Pediatric residents at six university hospitals Korea completed a survey consisting four questions. Each question proposed unique...
Immunoglobulin A nephropathy (IgAN) is one of the most common primary glomerulopathies diagnosed in children and adolescents. This study aimed to evaluate clinical features outcomes pediatric IgAN over last 30 years. Patients who were before age 18 at 20 centers Korea evaluated retrospectively. Of 1154 patients (768 males, 386 females) with a median follow-up 5 years, 5.6% (n = 65) progressed stage 3–5 chronic kidney disease (CKD). The 10- 20-year CKD-free survival rates 91.2% 75.6%,...
There have been several reports suggesting that the deficiency of complement 4 (C4) and/or deletion C4 genes are genetic risk factors in patients with IgA nephropathy (IgAN) and Henoch-Schönlein nephritis (HSN). In current study, we tried to clarify structure deleted as well isotype patients. Also, investigated DQB DRB which located near identify a possible linkage find associated allele. Our results showed locus II C4, not C4B sequence loss, is factor for these diseases gene can be either...
Deletion polymorphism of angiotensin I converting enzyme <i>(ACE)</i> gene has been studied as a risk factor in various cardiovascular diseases and chronic nephropathies. Perturbation local systemic renin-angiotensin systems is one the possible mechanisms progression reflux nephropathy. In this study, implication <i>ACE </i>gene renal scarring deterioration function was analyzed 66 children with vesicoureteral reflux. The genotype for determined by PCR, scar...
Objective To identify markers of disease and steroid responsiveness in paediatric idiopathic nephrotic syndrome. Methods Whole-transcriptome sequencing was performed peripheral blood mononuclear cells (PBMCs) from patients with NS. Differentially expressed genes (DEGs) were identified active NS vs those remission, steroid-sensitive (SSNS) steroid-resistant (SRNS). Results A total 1065 DEGs ( n = 10) remission 9). These correlated cytokine and/or immune system signalling the extracellular...
A retrospective genotype and phenotype analysis of X-linked congenital nephrogenic diabetes insipidus (NDI) was conducted on a nationwide cohort 25 (24 male, 1 female) Korean children with AVPR2 gene mutations, comparing non-truncating truncating mutations. In an male patients, the median age at diagnosis 0.9 years old. At follow-up 5.4 years, urinary tract dilatations were evident in 62% patients their glomerular filtration rate 72 mL/min/1.73 m2. Weights heights under 3rd percentile 22%...
Abstract The genetic spectrum of kidney diseases (GKD) and the application diagnoses to patient care were assessed by whole exome sequencing (WES) DNA 172 pediatric or adult patients with various diseases. WES diagnosed in 63 (36.6%) patients. diagnostic yields glomerulopathy 33.8% (25/74 pts) due variants 10 genes, 58.8% (20/34) tubulointerstitial disease 18 33.3% (15/45) cystic disease/ciliopathy 18.2% (2/11) congenital anomalies kidneys urinary tract (CAKUT) two 12.5% (1/8) end stage...
Toxic epidermal necrolysis (TEN) is a drug-related fatal disease. Extensive necrosis of the epidermis can lead to serious complications. This report describes two cases TEN, associated with deflazacort (DFZ), in boys, aged 4 years and 14 years, nephrotic syndrome (NS). The 14-year-old male teenager received DFZ following NS relapse. After 17 days, pruritic papules appeared on lower extremities. Another case involved 4-year-old boy receiving enalapril. 41-day treatment period, erythematous...
Purpose Influenza virus is one of the most important viruses that cause respiratory infection seasonally. In April 2009, H1N1 was detected in America and Mexico then there pandemic Korea. We investigated difference clinical laboratory findings between infections B. Methods have retrospectively studied patients under age 15 years who visited Inje University Sanggye Paik Hospital from August 2009 to 2010. Evaluation for influenza performed by rapid antigen test or multiplex reverse...
Toxic epidermal necrolysis (TEN) is a rare, acute and life-threatening cutaneous drug reaction. TEN characterized by the sudden onset of extensive necrosis in epidermis frequent mucous membrane involvement. The pathogenesis has not yet been elucidated. In addition, no particular treatment for established. We report case 14-year-old-boy, which might have caused steroids with enalapril membranous nephropathy. He recovered after intravenous immunoglobulin therapy.
Purpose : The aim of this study was to evaluate the clinical usefulness measurement β 2 microglobulin (β MG), N-acetyl-β-D-glucosaminidase (NAG) spot urine samples as indices renal tubular damage and microalbumin a parameter glomerular in children with vesicoureteral reflux (VUR) or defects.Methods We studied 91 previous UTI.The were classified 62 without VUR defects (group I), 10 VUR, II), 19 III).Patients having separated according degree (mild VUR: grade I-III, severe IV-V).Urinary...
Purpose To determine the relationship between vaginal reflux (VR) and urinary tract infection (UTI) in female children aged <36 months. Methods A single center retrospective study was performed for 191 girls months, with a diagnosis of febrile UTI, who underwent voiding cystourethrography (VCUG) assessment vesicoureteral (VUR) at Sanggye Paik Hospital. Fifty-one girls, VCUG congenital hydronephrosis or renal pelvis dilatation, without formed control group. The correlation presence grade VR...
Purpose:It is difficult to make a distinction between lower urinary tract infection(UTI) and acute pyelonephritis(APN) during the phase of febrile UTI due nonspecific clinical symptoms laboratory findings, especially among young children. We measured serum procalcitonin(PCT) in children with distinguish pyelonephritis UTI, determine accuracy PCT measurement compared other inflammatory markers. Methods:Serum samples were taken from who admitted unexplained fever or suspected having UTI. 51...
목 적 : 지금까지 코로나바이러스는 대부분 상기도 감염을 일으키며 임상적으로 큰 의미가 없는 것으로 여겨져 왔다. 하지만 최근에 발견된 코로나 바이러스인 hCoV-NL63와 hCoV-HKU1는 하부 호흡기 질환과의 연관성이 있는 보고되면서 임상적 의의에 대한 연구가 필요한 실정이다. 이에 저자들은 폐렴으로 입원한 ...
Chyluria is the passage of milky urine due to leakage lymph into urinary tract. occurs predominantly in adults and rare children. We present an unusual case which a child with proteinuria, hematuria was subsequently diagnosed non-parasitic chyluria. Retrograde cystogram confirmed lymphatico-calyceal communication. This showed spontaneous remission. The etiology this not exactly known; however, prognosis chyluria (or idiopathic chyluria) usually very good treatment mostly conservative.